EC Number   |
Substrates |
Organism |
Products |
Reversibility  |
|---|
   6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
converts linear molecules of polyriboadenylate to circular form by the intramolecular covalent linkage of the 5'-phosphate end to the 3'-hydroxyl terminus |
Tequatrovirus T4 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
formation of a phosphodiester bond between a 5'-PO4-terminated oligonucleotide and a 3'-OH terminated oligonucleotide. Intramolecular formation of single-stranded circles with longer oligonucleotides of the type pAp(Ap)nAOH, where n is about 15 or greater. Intermolecular joining of pAp(Ap)3AOH, where the 5'-PO4-terminated oligonucleotide is short enough to prevent apposition of its 3' and 5' ends, to UpUpUOH |
Tequatrovirus T4 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
cylization of poly(A) |
Tequatrovirus T4 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
the best substrate is [5'-P]polyriboadenylate |
Tequatrovirus T4 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
ligates two substrate RNAs, promoting the attack of the 3'-hydroxyl of one substrate upon the 5'-triphosphate of the other substrate with release of diphosphate, reverse of ligation has been detected, but very inefficient, not saturable by soluble amounts of diphosphate |
synthetic construct |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
catalyzes RNA end-joining |
Vibrio phage KVP40 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
catalyzes the transfer of AMP from the E-AMP complex to diverse compounds, generating the product indicated between parentheses, ATP(Ap4A), NTP (Ap4N), P3 or P4 (p4A or p5A), ADP (Ap3A) |
Tequatrovirus T4 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
participates in repair, splicing and editing pathways, reseals broken RNAs or alters their primary structure, catalyzes intramolecular and intermolecular RNA strand joining through ligase-adenylate and RNA adenylate intermediates |
Tequatrovirus T4 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
RNA editing, essential for proliferation of Trypanosoma brucei |
Trypanosoma brucei |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
RNA editing, posttranscriptional insertion and deletion of uridylate residues in mitochondrial transcripts |
Trypanosoma brucei |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
