EC Number   |
Substrates |
Organism  |
Products |
Reversibility |
|---|
   6.5.1.3 | more |
wheat RNA ligase can be dissected into three isolated domain enzymes that are responsible for its core ligase, 5'-kinase, and 2',3'-cyclic phosphate 3'-phosphodiesterase activities, respectively. A side reaction on 5'-tri/diphosphate RNAs is dependent on ATP, a 2'-phosphate-3'-hydroxyl end, and the ligase domain. Two RNA molecules having 5'-hydroxyl and 2',3'-cyclic monophosphate groups are ligated almost stoichiometrically after separate conversion of respective terminal phosphate states into reactive ones |
Triticum aestivum |
? |
- |
? |
| 6.5.1.3 | more |
wheat RNA ligase contains 5'-hydroxyl kinase, 2',3'-cyclic phosphate 3'-phosphodiesterase, and 5'-phosphate 2'-phosphate-3'-hydroxyl RNA ligase activities |
Triticum aestivum |
? |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
- |
Trypanosoma brucei |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
RNA editing, essential for proliferation of Trypanosoma brucei |
Trypanosoma brucei |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
RNA editing, posttranscriptional insertion and deletion of uridylate residues in mitochondrial transcripts |
Trypanosoma brucei |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
RNA editing, posttranscriptional process by which uridine residues are added and deleted from mitochondrial mRNAs |
Trypanosoma brucei |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
RNA editing, posttranscriptional RNA processing in which uridylate residues are inserted into and deleted from pre-mRNAs to create start and stop codons, also acts to reseal mRNAs cleaved at incorrect sites |
Trypanosoma brucei |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
RNA editing, unique U insertion and U deletion process, involves cycles of pre-mRNA cleavage, terminal U addition or U removal, and religation, band IV is the RNA editing ligase needed to seal in U deletion |
Trypanosoma brucei |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
the enzyme is essential for survival of both insect and bloodstream forms of the parasite |
Trypanosoma brucei |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
| 6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
- |
Vibrio phage KVP40 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
