EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
RNA substrates containing a 5'-phosphate terminus at one end and either a 2',3'-cyclic phosphate or a 2'-phosphate terminus at the other end. In the latter case the reaction is about 30% as active as with the cyclic derivative |
Triticum aestivum |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
participates in an in vitro splicing of yeast transfer RNA precursors containing intervening sequences. Covalently ligates tRNA5' and 3' half-molecules produced by a yeast endonuclease |
Triticum aestivum |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
conversion of linear polyribonucleotides into covalently closed circles, formation of a 2'-phosphomonoester,3',5'-phosphodiester linkage |
Triticum aestivum |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
converts linear molecules of polyriboadenylate to circular form by the intramolecular covalent linkage of the 5'-phosphate end to the 3'-hydroxyl terminus |
Tequatrovirus T4 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
formation of a phosphodiester bond between a 5'-PO4-terminated oligonucleotide and a 3'-OH terminated oligonucleotide. Intramolecular formation of single-stranded circles with longer oligonucleotides of the type pAp(Ap)nAOH, where n is about 15 or greater. Intermolecular joining of pAp(Ap)3AOH, where the 5'-PO4-terminated oligonucleotide is short enough to prevent apposition of its 3' and 5' ends, to UpUpUOH |
Tequatrovirus T4 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
cylization of poly(A) |
Tequatrovirus T4 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
the best substrate is [5'-P]polyriboadenylate |
Tequatrovirus T4 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
ligates two substrate RNAs, promoting the attack of the 3'-hydroxyl of one substrate upon the 5'-triphosphate of the other substrate with release of diphosphate, reverse of ligation has been detected, but very inefficient, not saturable by soluble amounts of diphosphate |
synthetic construct |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |
6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
only the di-magnesium-coordinated form Mg2ATP0 reacts with the enzyme, forming the covalent complex E-AMP, the reverse reaction, ATP synthesis, occurs between the mono-magnesium-coordinated diphosphate from MgP2O72- and the enzyme-MgAMP complex |
Tequatrovirus T4 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
r |
6.5.1.3 | ATP + (ribonucleotide)n + (ribonucleotide)m |
catalyzes RNA end-joining |
Vibrio phage KVP40 |
AMP + diphosphate + (ribonucleotide)n+m |
- |
? |