EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
    5.4.3.8 | (S)-4-Amino-5-oxopentanoate |
enzyme catalyzes the last step in the conversion of Glu to 5-amino-4-oxopentanoate |
Saccharolobus solfataricus P2 |
? |
- |
? |
| 5.4.3.8 | more |
enzyme GSAM catalyzes the transamination of GSA substrate to form 5-aminolevulinate by an unusual intramolecular exchange of amino and oxo groups via the intermediate 4,5-diaminovalerate (DAVA). The reaction starts with imine formation between pyridoxamine 5'-phosphate and the aldehyde of GSA. During the first half of the reaction pyridoxamine 5'-phosphate is converted to pyridoxal 5'-phosphate, while pyridoxamine 5'-phosphate is regenerated in the second half of the reaction upon 5-aminolevulinate formation |
Arabidopsis thaliana |
? |
- |
? |
| 5.4.3.8 | (S)-4-Amino-5-oxopentanoate |
formation of 5-aminolevulinic acid, which is the first committed precursor of chlorophyll biosynthesis in the chloroplast |
Chlamydomonas reinhardtii |
? |
- |
? |
| 5.4.3.8 | (S)-4-Amino-5-oxopentanoate |
induction of enzyme synthesis by light |
Hordeum vulgare |
? |
- |
? |
| 5.4.3.8 | (S)-4-amino-5-oxopentanoate |
involved in chlorophyll biosynthesis |
Brassica napus |
5-aminolevulinate |
- |
r |
| 5.4.3.8 | (S)-4-amino-5-oxopentanoate |
involved in conversion of glutamate to 5-aminolevulinate |
Synechococcus sp. |
5-aminolevulinate |
- |
r |
| 5.4.3.8 | 4,5-Diaminovalerate |
is a substrate for the pyridoxal 5'-phosphate form of the enzyme |
Escherichia coli |
? |
- |
? |
| 5.4.3.8 | 4,5-Diaminovalerate |
is a substrate for the pyridoxal 5'-phosphate form of the enzyme |
Pisum sativum |
? |
- |
? |
| 5.4.3.8 | 4,5-Diaminovalerate |
is a substrate for the pyridoxal 5'-phosphate form of the enzyme |
Synechococcus sp. |
? |
- |
? |
| 5.4.3.8 | 4,5-Dioxovalerate |
is a substrate for the pyridoxamine form of the enzyme |
Escherichia coli |
5-Amino-4-oxopentanoate |
- |
? |
