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EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
3.4.22.54
titin + H2O
-
Homo sapiens
?
-
?
3.4.22.54
titin + H2O
-
Sus scrofa
?
-
?
3.4.22.54
titin + H2O
-
Bos taurus
?
-
?
3.4.22.54
titin + H2O
calpain 3 expression is required for normal myofibril formation. Calpain 3 may influence the role of titin in sarcomere formation through proteolytic cleavage. The limb girdle muscular dystrophy 2A mutations in calpain C3 influence binding of calpain C3 to titin
Mus musculus
?
-
?
3.4.22.54
titin + H2O
the enzyme binds the C-terminus of titin at recognition motifs [LIMV]X(3,4) [LIMV]X(2)[LIMV][DE] and [LIMV]X(3,4)[LIMVA]X(2)[LIMV][DE]
Homo sapiens
?
-
?
3.4.22.54
titin + H2O
the enzyme binds the C-terminus of titin at recognition motifs [LIMV]X(3,4) [LIMV]X(2)[LIMV][DE] and [LIMV]X(3,4)[LIMVA]X(2)[LIMV][DE]
Mus musculus
?
-
?
3.4.22.54
triosephosphate isomerase + H2O
-
Homo sapiens
?
-
?
3.4.22.54
tropomyosin + H2O
-
Rattus norvegicus
?
-
?
3.4.22.54
troponin I + H2O
-
Rattus norvegicus
?
-
?
3.4.22.54
troponins T + H2O
-
Rattus norvegicus
?
-
?
Results
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