EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   3.4.21.7 | thrombin-activatable fibrinolysis inhibitor + H2O |
mutant variants with variants in the amino acids surrounding the scissile R92-A93 bond such as P91S, R92K, and S90P exhibit specific impairment of activation by plasmin |
Homo sapiens |
? |
- |
? |
| 3.4.21.7 | tissue factor pathway inhibitor + H2O |
plasmin increases tissue factor activity by inactivating the cell-associated tissue factor pathway inhibitor by a limited proteolysis |
Homo sapiens |
? |
- |
? |
| 3.4.21.7 | Tosyl-Arg methyl ester + H2O |
- |
Oryctolagus cuniculus |
? |
- |
? |
| 3.4.21.7 | Tosyl-Arg methyl ester + H2O |
p-tosyl-Arg methyl ester |
Homo sapiens |
? |
- |
? |
| 3.4.21.7 | tosyl-Gly-Pro-Lys-4-nitroanilide + H2O |
- |
Homo sapiens |
tosyl-Gly-Pro-Lys + 4-nitroaniline |
- |
? |
| 3.4.21.7 | transforming growth factor beta 2 + H2O |
- |
Homo sapiens |
? |
- |
? |
| 3.4.21.7 | TYK2 |
triggers tyrosine phosphorylation |
Homo sapiens |
? |
- |
? |
| 3.4.21.7 | vascular endothelial growth factor + H2O |
cleavage site: Arg110-/-Ala111. The mutant vascular endothelial growth factors R110A, R110Q and A111P are resistant to cleavage |
Homo sapiens |
? |
- |
? |
| 3.4.21.7 | vascular endothelial growth factor + H2O |
in non-healing wounds plasmin cleaves and inactivates vascular endothelial growth factor VEGF165 |
Homo sapiens |
? |
- |
? |
| 3.4.21.7 | von Willebrand factor + H2O |
the enzyme cleaves von Willebrand factor at K1491-R149. Globular von Willebrand factor is resistant to plasmin cleavage under static conditions, but is readily cleaved by plasmin under shear |
Homo sapiens |
? |
- |
? |
