EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   3.3.2.9 | more |
no activity with [5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl][3-(4-[[methyl(oxetan-3-yl)amino]methyl]phenoxy)azetidin-1-yl]methanone, [5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl][3-(4-[[(3-methyloxetan-3-yl)amino]methyl]phenoxy)azetidin-1-yl]methanone, 2-(4-methoxyphenyl)-N-[(3-methyloxetan-3-yl)methyl]ethan-1-amine, and 2-(4-methoxyphenyl)-N-methyl-N-[(oxetan-3-yl)methyl]ethan-1-amine |
Homo sapiens |
? |
- |
? |
| 3.3.2.9 | more |
not active with trans-1,3-diphenylpropene oxide |
Rattus norvegicus |
? |
- |
? |
| 3.3.2.9 | more |
oxetanes are a nonepoxide class of substrates for human mEH, which is known to catalyze the hydrolytic ring opening of electrophilic and potentially toxic epoxide-containing drugs, drug metabolites, and exogenous organochemicals |
Homo sapiens |
? |
- |
? |
| 3.3.2.9 | juvenile hormone III + H2O |
poor substrate |
Heliothis virescens |
? |
- |
? |
| 3.3.2.9 | more |
potent and selective induction by trans-stilbene oxide |
Rattus norvegicus |
? |
- |
? |
| 3.3.2.9 | (R)-styrene oxide + H2O |
preferential hydrolysis of the (R)-enantiomer |
Phanerodontia chrysosporium |
(R)-styrene glycol |
- |
? |
| 3.3.2.9 | cyano-(6-methoxynaphthalen-2-yl)methyl trans-2-pentenylacetate + H2O |
prepared from trans-styrylacetic acid and 7-methoxy-2-naphthaldehyde. Enzyme EH catalyzed hydrolysis of the epoxide substrate produces an intermediate diol which lactonizes to release a fluorescent reporter after hydrolysis of the intermediate cyanohydrin |
Karenia brevis |
? |
- |
? |
| 3.3.2.9 | more |
probably represents an important factor in the control of reactive epoxides |
Mus musculus |
? |
- |
? |
| 3.3.2.9 | (R)-styrene oxide + H2O |
R-enantiomer is preferred |
Mugil cephalus |
(1R)-1-phenylethane-1,2-diol |
- |
? |
| 3.3.2.9 | styrene oxide + H2O |
recombinant enzyme, low activity |
Glycine max |
1-phenylethane-1,2-diol |
- |
? |
