EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
3.3.2.6 | (7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate + H2O |
- |
Cricetulus sp. |
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate |
- |
? |
3.3.2.6 | leukotriene A4 + H2O |
- |
Danio rerio |
leukotriene B4 |
- |
? |
3.3.2.6 | leukotriene A4 + H2O |
leukotriene A4 hydrolase catalyzes the final step in the synthesis of leukotriene B4, a potent chemoattractant and proinflammatory eicosanoid. LTB4 functions as a macrophage chemoattractant in the zebrafish, injection into the hindbrain ventricle of wild-type arvae induces rapid recruitment of macrophages |
Danio rerio |
leukotriene B4 |
- |
? |
3.3.2.6 | (7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate + H2O |
- |
Homo sapiens |
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate |
- |
? |
3.3.2.6 | (7E,9E,11Z,14Z)-(5S,6S)-5,6-epoxyicosa-7,9,11,14-tetraenoate + H2O |
substrate for the epoxide hydrolase reaction, in addition LTA4H shows a peptidase activity |
Homo sapiens |
(6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate |
- |
? |
3.3.2.6 | Ala-4-nitroanilide + H2O |
- |
Homo sapiens |
Ala + 4-nitroaniline |
- |
? |
3.3.2.6 | Arg-Ala-Arg + H2O |
- |
Homo sapiens |
? |
- |
? |
3.3.2.6 | Arg-Ser-Arg + H2O |
- |
Homo sapiens |
? |
- |
? |
3.3.2.6 | L-Ala-4-nitroanilide + H2O |
- |
Homo sapiens |
L-Ala + 4-nitroaniline |
- |
? |
3.3.2.6 | L-Ala-p-nitroanilide + H2O |
- |
Homo sapiens |
L-Ala + p-nitroaniline |
- |
? |