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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.6leukotriene A4 + H2O - Canis lupus familiaris leukotriene B4 i.e. LTB4, a potent inflammatory mediator originating from membrane-derived arachidonic acid ?
Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.6leukotriene A4 + H2O - Homo sapiens leukotriene B4 i.e. LTB4, a powerful proinflammatory agent ?
Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.6leukotriene A4 + H2O LTA4 Homo sapiens leukotriene B4 LTB4 ?
Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.6leukotriene A4 + H2O - Mus musculus leukotriene B4 LTB4 is an endogenous itch mediator in the skin and is involved in the pruritus response in allergic reactions ?
Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.6leukotriene A4 + H2O model for the binding of leukotriene A4 to the active site Cavia porcellus leukotriene B4 mutants of Tyr378 are able to generate, not only leukotriene B4, but also (5S,12R)-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid, in a yield of about 20-30% ?
Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.6leukotriene A4 + H2O model for the binding of leukotriene A4 to the active site Mus musculus leukotriene B4 mutants of Tyr378 are able to generate, not only leukotriene B4, but also (5S,12R)-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid, in a yield of about 20-30% ?
Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.6leukotriene A4 + H2O model for the binding of leukotriene A4 to the active site Homo sapiens leukotriene B4 mutants of Tyr378 are able to generate, not only leukotriene B4, but also (5S,12R)-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid, in a yield of about 20-30% ?
Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.6leukotriene A4 + H2O model for the binding of leukotriene A4 to the active site Rattus norvegicus leukotriene B4 mutants of Tyr378 are able to generate, not only leukotriene B4, but also (5S,12R)-dihydroxy-6,10-trans-8,14-cis-eicosatetraenoic acid, in a yield of about 20-30% ?
Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.6leukotriene A4 + H2O - Xenopus laevis leukotriene B4 + 5(S),12R-dihydroxy-6,10-trans-8,14-ciseicosatetraenoic acid product ratio 9:1 ?
Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.6leukotriene A4 + H2O - Saccharomyces cerevisiae (5S,6S)-dihydroxy-7,9-trans-11,14-cis-eicosatetraenoic acid + leukotriene B4 + (5S,12R)-dihydroxy-6,10-trans-8,14,cis-eicosatetraenoic acid when large amounts of enzyme are incubated with leukotriene A4: 72% (5S,6S)-dihydroxy-7,9-trans-11,14-cis-eicosatetraenoic acid, 18% leukotriene B4 and 10% (5S,12R)-dihydroxy-6,10-trans-8,14,cis-eicosatetraenoic acid ?
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