EC Number   |
Substrates |
Organism  |
Products |
Reversibility |
|---|
   2.7.11.10 | ATP + IkappaB alpha |
- |
Homo sapiens |
ADP + phosphorylated IkappaB alpha |
- |
? |
| 2.7.11.10 | ATP + IkappaB protein |
- |
Homo sapiens |
ADP + IkappaB phosphoprotein |
- |
? |
| 2.7.11.10 | ATP + IkappaBalpha |
- |
Homo sapiens |
ADP + phosphorylated IkappaBalpha |
- |
? |
| 2.7.11.10 | ATP + IkappaBalpha |
a step in NF-kappaB activation, the IKK complex, composed of IKKalpha, IKKbeta, and NEMO/IKKgamma, is the convergence point for many diverse NFkappaB-activating stimuli including TNFalpha, LPS, and IL-1, overview, IKKbeta is the primary positive regulator of NFkappaB activity in inflammatory processes, is the molecular link between inflammation and cancer |
Homo sapiens |
ADP + phosphorylated IkappaBalpha |
- |
? |
| 2.7.11.10 | ATP + IkappaBalpha |
degradation of IkappaBalpha |
Homo sapiens |
ADP + phosphorylated IkappaBalpha |
- |
? |
| 2.7.11.10 | ATP + IkappaBalpha |
recombinant GST-fusion substrate |
Homo sapiens |
ADP + phosphorylated IkappaBalpha |
- |
? |
| 2.7.11.10 | ATP + IkappaBalpha |
phosphorylation at Ser-32 and Ser-36 |
Homo sapiens |
ADP + phosphorylated IkappaBalpha |
- |
? |
| 2.7.11.10 | ATP + interferon regulatory factor 3 |
- |
Homo sapiens |
ADP + phosphorylated interferon regulatory factor 3 |
- |
? |
| 2.7.11.10 | ATP + KKKKERLLDDRHDSGLDSMKDEE |
IKK substrate peptide derived from IkappaBalpha sequence |
Homo sapiens |
ADP + phosphorylated-KKKKERLLDDRHDSGLDSMKDEE |
- |
? |
| 2.7.11.10 | ATP + NF-kappaB |
- |
Homo sapiens |
ADP + phosphorylated NF-kappaB |
- |
? |
