EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.7.11.10 | ATP + [RelA/p65 protein] |
phosphorylation on Ser536 of the transactivation domain, dependent on lipopolysaccharide-induction, but not on Akt or p65 |
Mus musculus |
ADP + [RelA/p65 phosphoprotein] |
- |
? |
2.7.11.10 | ATP + [S386A IFN regulatory factor 3 protein] |
the mutant substrate is equally phosphorylated as the wild-type IRF3 |
Mus musculus |
ADP + [S386A IFN regulatory factor 3 phosphoprotein] |
- |
? |
2.7.11.10 | ATP + [S396A IFN regulatory factor 3 protein] |
the mutant substrate is equally phosphorylated as the wild-type IRF3 |
Mus musculus |
ADP + [S396A IFN regulatory factor 3 phosphoprotein] |
- |
? |
2.7.11.10 | ATP + [S402A/S404A/S405A IFN regulatory factor 3 protein] |
low activity with the IRF3 mutant |
Mus musculus |
ADP + [S402A/S404A/S405A IFN regulatory factor 3 phosphoprotein] |
- |
? |