EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.4.2.30 | more |
the enzyme also targets deoxyguanosine |
Streptomyces scabiei |
? |
- |
? |
2.4.2.30 | more |
the enzyme also targets deoxyguanosine |
Streptomyces scabiei 87.22 |
? |
- |
? |
2.4.2.30 | NAD+ + histone H2A |
the enzyme catalyses both ADP-ribosylation and deacetylation of histones, particulary H2A and H2B |
Trypanosoma brucei |
nicotinamide + (ADP-D-ribosyl)-histone H2A |
- |
? |
2.4.2.30 | NAD+ + histone H2B |
the enzyme catalyses both ADP-ribosylation and deacetylation of histones, particulary H2A and H2B |
Trypanosoma brucei |
nicotinamide + (ADP-D-ribosyl)-histone H2B |
- |
? |
2.4.2.30 | NAD+ + histone H2A |
the enzyme catalyses both ADP-ribosylation and deacetylation of histones, particulary H2A and H2B. Histone modification by TbSIR2RP1 is involved in DNA repair |
Trypanosoma brucei |
nicotinamide + (ADP-D-ribosyl)-histone H2A |
- |
? |
2.4.2.30 | NAD+ + histone H2B |
the enzyme catalyses both ADP-ribosylation and deacetylation of histones, particulary H2A and H2B. Histone modification by TbSIR2RP1 is involved in DNA repair |
Trypanosoma brucei |
nicotinamide + (ADP-D-ribosyl)-histone H2B |
- |
? |
2.4.2.30 | more |
the enzyme has the ability to ADP-ribosylate itself |
Homo sapiens |
? |
- |
? |
2.4.2.30 | NAD+ + (ADP-D-ribosyl)n-acceptor |
the enzyme is a DNA repair enzyme |
Bos taurus |
nicotinamide + (ADP-D-ribosyl)n+1-acceptor |
- |
? |
2.4.2.30 | more |
the enzyme is involved in endothelial cell dysfunction |
Mus musculus |
? |
- |
? |
2.4.2.30 | more |
the enzyme is involved in endothelial cell dysfunction |
Mus musculus 129/Sv x C57BL/6 |
? |
- |
? |