EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   2.4.1.90 | more |
the enzyme is part of the endoplasmic reticulum and Golgi glycosylation network, glycosyltransferase metabolism, overview |
Cricetulus griseus |
? |
- |
? |
| 2.4.1.90 | more |
the preexisting alpha-lactalbumin-binding site iss utilized during mammalian evolution to synthesize lactose in the mammary gland during lactation |
Drosophila melanogaster |
? |
- |
? |
| 2.4.1.90 | more |
tumor beta-1,4-galactosyltransferase IV overexpression is closely associated with colorectal cancer metastasis and poor prognosis, relationships between tumor beta-1,4-GT-IV overexpression and clinicopathologic characteristics, overview |
Homo sapiens |
? |
- |
? |
| 2.4.1.90 | more |
beta-1,4-GTs are a family of glycosyltransferases responsible for biosynthesizing N-acetyllactosamine by the transfer of a galactose from UDP-galactose to the terminal N-acetylgluosamine of acceptor sugars in glycoproteins or glycolipids with a beta-1,4-linkage |
Homo sapiens |
? |
- |
? |
| 2.4.1.90 | more |
substrate specificity in presence or absence of alpha-lactalbumin, overview, the 'specifier' protein alpha-lactalbumin, which interacts with beta-1,4-GalT forming the lactose synthase complex, EC 2.4.1.22, is not necessary when the acceptors are different glucopyranosides, EC 2.4.1.38, and, in some cases, it can even have an inhibitory effect, e.g. in reaction with the complex glucosides ginsenoside Rg1 and colchicoside, overview |
Bos taurus |
? |
- |
? |
| 2.4.1.90 | more |
substrate specificity of wild-type and mutant Y289L enzymes, overview |
Homo sapiens |
? |
- |
? |
| 2.4.1.90 | more |
the enzyme catalyzes the transfer of Gal from UDP-Gal to GlcNAc-terminating acceptors with inversion of configuration of the glycosidic linkage, in presence of beta-lactalbumin, the enzyme changes its specificity to become lactose synthase, EC 2.4.1.22, and transfers Gal to glucose to synthesize lactose, substrate specificity, e.g. with GlcNAc-terminating O-glycopeptides, no activity with N-trimethylacetyl-GlcN, N,N-dimethyl-GlcN, N-isopropyl-GlcN, and N-(4-MeOBn)GlcN, overview |
Bos taurus |
? |
- |
? |
| 2.4.1.90 | more |
beta1,4-galactosyltransferase II is one of the enzymes transferring galactose to the terminal N-acetylglucosamine of complex-type N-glycans. Beta1,4GalT II might serve as a target gene of p53 transcription factor during adriamycin-induced HeLa cell apoptosis, mechanisms of its expression regulation, overview |
Homo sapiens |
? |
- |
? |
| 2.4.1.90 | more |
the enzyme is one of the key molecules on the sperm surface, and is likely to be involved in binding to the egg coat, the zona pelludica, to mediate sperm-egg interaction |
Trichosurus vulpecula |
? |
- |
? |
| 2.4.1.90 | more |
substrate specificity, coupling of 6-azido-6-deoxy D-galactose to a GlcNAc-terminated substrate, method development for usage of the enzyme reaction for tagging glycoproteins carrying terminal GlcNAc, overview |
Bos taurus |
? |
- |
? |
