EC Number   |
Substrates |
Organism |
Products |
Reversibility |
|---|
   1.7.1.13 | 5-cyanopyrrolo[2,3-d]pyrimidin-4-one + 2 NADPH + 2 H+ |
analogue of natural substrate |
Escherichia coli |
5-amino-methyl-pyrrolo[2,3-d]pyrimidin-4-one + 2 NADP+ |
- |
? |
| 1.7.1.13 | 2-amino-5-cyanopyrrolo[2,3-d]pyrimidine + 2 NADPH + 2 H+ |
analogue of natural substrate, poor substrate |
Escherichia coli |
2-amino-5-amino-methyl-pyrrolo[2,3-d]pyrimidine + 2 NADP+ |
- |
? |
| 1.7.1.13 | more |
during catalysis each active site of the dimeric enzyme binds one substrate molecule. NADPH binds independent of the substrate. The PreQ0 binding pocket of the active site is not involved in the binding of NADPH |
Escherichia coli |
? |
- |
? |
| 1.7.1.13 | more |
enzyme is highly specific for substrate preQ0 |
Pectobacterium carotovorum subsp. carotovorum |
? |
- |
? |
| 1.7.1.13 | more |
enzyme is highly specific for substrate preQ0 |
Pectobacterium carotovorum subsp. carotovorum PCC21 |
? |
- |
? |
| 1.7.1.13 | 7-cyano-7-deazaguanine + 2 NADPH + 2 H+ |
i.e. preQ0 |
Escherichia coli |
7-aminomethyl-7-deazaguanine + 2 NADP+ |
- |
? |
| 1.7.1.13 | 7-cyano-7-deazaguanine + 2 NADPH + 2 H+ |
late step in biosynthesis of the modified tRNA nucleoside queuosine |
Bacillus subtilis |
queuine + 2 NADP+ |
- |
? |
| 1.7.1.13 | 7-cyano-7-deazaguanine + 2 NADPH + 2 H+ |
late step in biosynthesis of the modified tRNA nucleoside queuosine |
Escherichia coli |
queuine + 2 NADP+ |
- |
? |
| 1.7.1.13 | 2-amino-5-cyanopyrrolo[2,3-d]pyrimidin-4-one + 2 NADPH + 2 H+ |
natural substrate |
Escherichia coli |
2-amino-5-amino-methyl-pyrrolo[2,3-d]pyrimidin-4-one + 2 NADP+ |
- |
? |
| 1.7.1.13 | more |
no substrates: acetonitrile, benzonitrile and benzylcyanide |
Escherichia coli |
? |
- |
? |
