EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.17.1.8 | (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ |
- |
Escherichia coli |
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O |
- |
? |
1.17.1.8 | (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ |
- |
Arabidopsis thaliana |
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O |
- |
? |
1.17.1.8 | (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ |
- |
Neisseria meningitidis |
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O |
- |
? |
1.17.1.8 | (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ |
the enzyme catalyses the second reaction in the diaminopimelate pathway of lysine biosynthesis in bacteria and plants |
Selaginella moellendorffii |
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O |
- |
? |
1.17.1.8 | (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ |
the enzyme catalyses the second reaction in the diaminopimelate pathway of lysine biosynthesis in bacteria and plants |
Arabidopsis thaliana |
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O |
- |
? |
1.17.1.8 | (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ |
the enzyme catalyses the second reaction in the diaminopimelate pathway of lysine biosynthesis in bacteria and plants |
Vitis vinifera |
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O |
- |
? |
1.17.1.8 | (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ |
the enzyme catalyzes the second committed step in the diaminopimelate/lysine anabolic pathways |
Bartonella henselae |
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O |
- |
? |
1.17.1.8 | (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ |
the enzyme is involved in L-lysine biosynthesis |
Corynebacterium glutamicum |
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O |
- |
? |
1.17.1.8 | (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ |
it is proposed that the the domain movement for active site constitution occurs when both cofactor and substrate bind to the enzyme |
Corynebacterium glutamicum |
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O |
- |
? |
1.17.1.8 | (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+ |
the enzyme is involved in L-lysine biosynthesis |
Corynebacterium glutamicum ATCC 13032 |
(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O |
- |
? |