EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
1.14.99.38 | cholesterol + AH2 + O2 |
production of 25-hydroxycholesterol by intact CYP3A4, most significant activity is 25-hydroxylation, which is higher than that of 4beta-hydroxylation, a marker activity of CYP3A4 |
Homo sapiens |
25-hydroxycholesterol + A + H2O |
- |
? |
1.14.99.38 | cholesterol + AH2 + O2 |
the reaction might be catalyzed by CYP3A4 |
Homo sapiens |
25-hydroxycholesterol + A + H2O |
- |
? |
1.14.99.38 | cholesterol + AH2 + O2 |
the reaction might be catalyzed by CYP3A4 |
Mus musculus |
25-hydroxycholesterol + A + H2O |
- |
? |
1.14.99.38 | more |
25-hydroxycholesterol is a secondary autoxidation product derived from 3beta-hydroxy-cholest-5-ene-25-hydroperoxide, a hydroperoxide identified in air-aged cholesterol. Thermal decomposition of 3beta-hydroxy-cholest-5-ene-25-hydroperoxide gives rise to 25-hydroxycholesterol |
Rattus norvegicus |
? |
- |
? |
1.14.99.38 | more |
25-hydroxycholesterol is a secondary autoxidation product derived from 3beta-hydroxy-cholest-5-ene-25-hydroperoxide, a hydroperoxide identified in air-aged cholesterol. Thermal decomposition of 3beta-hydroxy-cholest-5-ene-25-hydroperoxide gives rise to 25-hydroxycholesterol |
Sus scrofa |
? |
- |
? |
1.14.99.38 | more |
25-hydroxycholesterol is a secondary autoxidation product derived from 3beta-hydroxy-cholest-5-ene-25-hydroperoxide, a hydroperoxide identified in air-aged cholesterol. Thermal decomposition of 3beta-hydroxy-cholest-5-ene-25-hydroperoxide gives rise to 25-hydroxycholesterol |
Homo sapiens |
? |
- |
? |
1.14.99.38 | more |
25-hydroxycholesterol is a secondary autoxidation product derived from 3beta-hydroxy-cholest-5-ene-25-hydroperoxide, a hydroperoxide identified in air-aged cholesterol. Thermal decomposition of 3beta-hydroxy-cholest-5-ene-25-hydroperoxide gives rise to 25-hydroxycholesterol |
Mus musculus |
? |
- |
? |