ATP + (ribonucleotide)n + (ribonucleotide)m
possibly involved in posttranscriptional RNA editing process of mitochondrial transcripts
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ATP + (ribonucleotide)n + (ribonucleotide)m
possibly involved in posttranscriptional RNA editing process of mitochondrial transcripts
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ATP + etidronate
weak activity
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joins single-stranded DNA molecules much less efficiently. Many of them approximate a well-defined consensus sequence
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RNA-stimulated exchange reaction between ATP and diphosphate
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efficient ligation of single-stranded DNAs and RNAs
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synthesizes circular hammerhead ribozymes from oligonucleotides, small RNA molecules resistant to circuarization by other means can be efficiently circularized on a preparative scale using a suitable DNA template
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no activity with alendronate nor pamidronate
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the group I intron from cyanobacterium Anabaena sp. catalyzes phosphodiester bond formation using a triphosphate on the 5'-terminal nucleotide, much like protein polymerases and engineered ribozymes. In the process, this ribozyme forms a unique circular RNA that incorporates the exogenous guanosine cofactor added during self-splicing
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enzyme does not discriminate between RNA and DNA for phosphodiester bond formation
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