Search Substrates and Products (Substrate)

2.7.11.10

ATP + [IRF3 protein]

phosphorylation at Ser396 by IKK-related IKKepsilon and TBK1 kinase

ADP + [IRF3 phosphoprotein]

?

2.7.11.10

ATP + [leucine-rich repeat kinase 2 protein]

catalyzed reaction of canonical IKKalpha and IKKbeta and IKK-related IKKepsilon and TBK1 kinase

ADP + [leucine-rich repeat kinase 2 phosphoprotein]

?

2.7.11.10

ATP + [leucine-rich repeat kinase 2 protein]

phosphorylation of LRRK2 at Ser910 and Ser935 by IKKalpha and IKKbeta

ADP + [leucine-rich repeat kinase 2 phosphoprotein]

?

2.7.11.10

ATP + [NFkappaB subunit p56]

ADP + [NFkappaB subunit p56]phosphate

?

2.7.11.10

ATP + [NFkappaB subunit p56]

phosphorylation at serine residues, especially at S536, in the cytoplasm prior to NFkappaB p56 translocation to the nucleus

ADP + [NFkappaB subunit p56]phosphate

?

2.7.11.10

ATP + [optineurin protein]

phosphorylation at Ser177 by IKK-related IKKepsilon and TBK1 kinase

ADP + [optineurin phosphoprotein]

?

2.7.11.10

ATP + [p73 protein]

IKKalpha in the nucleus

ADP + [p73 phosphoprotein]

?

2.7.11.10

ATP + [RelA/p65 protein]

ADP + [RelA/p65 phosphoprotein]

?

2.7.11.10

ATP + [RelA/p65 protein]

phosphorylation on Ser536 of the transactivation domain, dependent on lipopolysaccharide-induction, but not on Akt or p65

ADP + [RelA/p65 phosphoprotein]

?

2.7.11.10

ATP + [S386A IFN regulatory factor 3 protein]

the mutant substrate is equally phosphorylated as the wild-type IRF3

ADP + [S386A IFN regulatory factor 3 phosphoprotein]

?