Refine search

Search Substrates and Products (Substrate)

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search

Search term:

<< < Results 131 - 140 of 142 > >>
EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
more
IKKalpha is not only a regulator of mammary epithelial proliferation, but is also an important contributor to ErbB2-induced oncogenesis, providing signals that maintain mammary tumor-initiating cells, IKKalpha activity is required for cyclin D1 induction and proliferation of lobuloalveolar epithelial cells, and is required for self-renewal of ErbB2/Her2-transformed mammary tumor-initiating cells, overview
?
-
-
more
IKKbeta subunit of IKK complex is essential for the activation of NF-kappaB in response to various proinflammatory signals, Cys179 of IkappaB kinase beta plays a critical role in enzyme activation by promoting phosphorylation of activation loop serines, overview
?
-
-
more
IKKepsilon is important in the regulation of the alternative NF-kappaB activation pathway involving p52 and p65, IKKepsilon interacts with p52 and promotes transactivation via p65
?
-
-
more
IKKepsilon, i.e. IKKi, is implicated in virus induction of interferon-beta, IFNbeta, and development of immunity, IKKepsilon functions in a redundant role to its ubiquitous counterpart, TBK1, in the activation of IRF3 and IRF7 ex vivo, IKKe determines ISGF3 binding specificity, regulaiton, overview
?
-
-
more
mechanisms/pathways of activation and derepression of the IKK complex, regulation, detailed overview
?
-
-
more
the IkappaB kinase regulates chromatin structure during reconsolidation of conditioned fear memories, IKKalpha is involved in the regulation of histone H3 phosphorylation and acetylation at specific gene promoters in hippocampus in the NF-kappaB pathway, inhibition of IKKalpha regulation results in impairments in fear memory reconsolidation, mechanism, overview
?
-
-
more
IKKalpha interacts with p73
?
-
-
more
interaction analysis of IKKepsilon with NF-kappaB complex components/p25/p65 by immunoprecipitation and mass spectrometric analysis, overview
?
-
-
more
no activity with Rip2
?
-
-
more
the enzyme activity is included in a complex formed of the scaffold protein NF-kappaB essential modulator, i.e. NEMO or IKKgamma, and the Ikkalpha and IKKbeta kinases, overview
?
-
-
<< < Results 131 - 140 of 142 > >>