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<< < Results 11 - 20 of 21 > >>
EC Number
Substrates
Commentary Substrates
Organism
Products
Commentary (Products)
Reversibility
precorrin-3A + NADH + H+ + O2
-
precorrin-3B + NAD+ + H2O
-
ir
precorrin-3A + NADH + H+ + O2
pathway to coenzyme B12, biosynthesis of the corrin macrocycle, catalyzes a complex oxidative reaction involving C20 hydroxylation and gamma-lactone formation from ring-A acetate to C1
precorrin-3B + NAD+ + H2O
-
ir
precorrin-3A + NADH + H+ + O2
the Brucella melitensis enzyme is fully active in vitro (20 mM Tris-HCl buffer, pH 8.0, with 100 mM NaCl, S-adenosyl-L-methionine (SAM), 5-aminolevulinic acid (ALA) and NADPH, aerobic, dark, 4°C) and the mononuclear non-heme iron is reducible by dithionite and then is able to react with NO as oxygen analogue in the presence of the substrate
precorrin-3B + NAD+ + H2O
-
?
precorrin-3A + NADH + H+ + O2
-
precorrrin-3B + NAD+ + H2O
aerobic incubation with CobG alone, if CobJ and S-adenosyl-L-methionine are included the product is precorrin-4
ir
precorrin-3A + NADH + H+ + O2
biosynthesis of vitamin B12
precorrrin-3B + NAD+ + H2O
aerobic incubation with CobG alone, if CobJ and S-adenosyl-L-methionine are included the product is precorrin-4
ir
precorrin-3A + NADH + H+ + O2
-
precorrrin-3B + NAD+ + H2O
aerobic incubation with CobG alone, if CobJ and S-adenosyl-L-methionine are included the product is precorrin-4
ir
precorrin-3A + NADH + H+ + O2
biosynthesis of vitamin B12
precorrrin-3B + NAD+ + H2O
aerobic incubation with CobG alone, if CobJ and S-adenosyl-L-methionine are included the product is precorrin-4
ir
precorrin-3A + NADH + O2
-
precorrin-3B + NAD+ + H2O
-
?
precorrin-3A + NADH + O2
the enzyme is involved in ring contraction, whereby an integral carbon atom of the tetrapyrrole-derived macrocycle is removed, and cobalt chelation during aerobic synthesis of vitamin B12, the catalytic cycle of CobZ, overview
precorrin-3B + NAD+ + H2O
-
?
precorrin-3A + NADH + O2
the enzyme generates a hydroxy lactone intermediate
precorrin-3B + NAD+ + H2O
-
?
<< < Results 11 - 20 of 21 > >>