EC Number   |
Specific Activity Minimum [µmol/min/mg] |
Specific Activity Maximum [µmol/min/mg] |
Reference |
|---|
   3.4.23.B1 | -999 |
- |
amounts and activities of napsin A studied by immunoblotting and specific substrate cleavage, general defect in napsin A expression or activity not observed as cause for abnormal surfactant accumulation in juvenile pulmonary alveolar proteinosis |
679675 |
| 3.4.23.B1 | -999 |
- |
expression of napsin A determined by mRNA in situ hybridization in renal cells, tumor-suppression activity determined, mutation of one of the aspartic acid residues in the napsin A catalytic site shown to affect enzyme activity but not processing, glycosylation or intracellular localization, napsin A shown to inhibit tumor growth of transformed cells by a mechanism independent of its catalytic activity |
683839 |
| 3.4.23.B1 | -999 |
- |
napsin A as a diagnostic marker for lung adenocarcinoma tested, comparative study between napsin A and thyroid transcription factor TTF-1 by immunohistochemical analysis, napsin A reactivity in more than 75% of the tumor cells in 9/10 positive cases obtained, napsin A shown to be useful as an alternative marker to thyroid transcription factor TTF-1 in cytological diagnosis of effusions with low amounts of tumor cells |
683396 |
| 3.4.23.B1 | -999 |
- |
napsin A-expressing cells shown to form tumors in SCID mice with lower efficiency and slower onset compared to vector-transfected control cells |
683839 |
