EC Number |
Specific Activity Minimum [µmol/min/mg] |
Specific Activity Maximum [µmol/min/mg] |
Reference |
---|
3.4.21.78 | -999 |
- |
- |
29736 |
3.4.21.78 | -999 |
- |
ability of human and mouse granzyme A to kill human or mouse cells in the presence of perforin analyzed by standard MTT-assay and by 51Cr-release assay, recombinant and native proteins tested, cytotoxic potential between mouse and human granzyme A different |
683694 |
3.4.21.78 | -999 |
- |
ability of human and mouse granzyme A to kill human or mouse cells in the presence of perforin analyzed, recombinant and native proteins tested, cytotoxic potential between mouse and human granzyme A different |
683694 |
3.4.21.78 | -999 |
- |
ability of human and mouse granzyme A to kill human or mouse cells in the presence of perforin analyzed, recombinant and native proteins tested, cytotoxic potential between mouse and human granzyme A different, mouse but not human granzyme A induces perforin-dependent cell death |
683694 |
3.4.21.78 | -999 |
- |
constitutive expression in human PMNs shown by flow cytometry, Western blot, enzyme-linked immunosorbent assay and quantitative RT-PCR, up-regulation upon PMN stimulation shown |
683529 |
3.4.21.78 | -999 |
- |
detection of extracellular granzyme A during disease reviewed, elevated levels during viral and bacterial infection, arthritis and other diseases |
683201 |
3.4.21.78 | -999 |
- |
enzymatic activity of granzyme A measured in lysates of CD8+ tumor associated lymphocytes of interleukin 4-deficient and wild-type BALB/c mice, significant increase in the fraction of CD8+ tumor associated T-cells expressing granzyme A identified, in interleukin 4-deficient mice, the frequency of CD8+ tumor associated lymphocytes expressing granzyme A significantly increases between days 8 and 14, expression at background levels by day 21, increase in the percentage of CD8+ tumor associated lymphocytes expressing granzyme A less pronounced in wild-type mice |
683326 |
3.4.21.78 | -999 |
- |
expression shown by flow cytometry, Western blot, enzyme-linked immunosorbent assay and quantitative RT-PCR, up-regulation of expression upon stimulation shown |
683529 |
3.4.21.78 | -999 |
- |
expression shown by flow cytometry, Western blot, enzyme-linked immunosorbent assay and quantitative RT-PCR, up-regulation upon stimulation shown |
683529 |
3.4.21.78 | -999 |
- |
glucocorticoid sensitivity among cell lines derived from acute lymphoblastic leukemia patients analyzed, correlation between glucocorticoid-induced apoptosis and glucocorticoid-induced mRNA expression of granzyme A shown |
683723 |