EC Number   |
Specific Activity Minimum [µmol/min/mg] |
Specific Activity Maximum [µmol/min/mg] |
Reference |
|---|
   2.1.1.67 | -999 |
- |
activity of TPMT in nmol of the formed 6-mMP/g Hb/h, dialyzed patients, total 30.6, females 30.1, males 31.7, control group, total 28.4, females 28.4, males 28.7 |
689369 |
| 2.1.1.67 | -999 |
- |
determination of thiopurine S-methyltransferase activity in erythrocytes using 6-thioguanine as substrate and a non-extraction liquid chromatographic technique. This method minimzes sample-handling, reduces inherent imprecision, the possibility of laboratory error and has a potential for further automation |
659566 |
| 2.1.1.67 | -999 |
- |
median TPMT activities, Singapore Chinese 16.4 U, Singapore Malays 17.8 U, Singapore Indians 16.4 U, one unit of activity is defined as a formation of 1 nmol of 6-methylmercaptopurine per ml of packed red blood cells per h incubation at 37°C |
686505 |
| 2.1.1.67 | -999 |
- |
normal thiopurine methyltransferase activity, 7.5-14 U/ml erythrocytes |
684275 |
| 2.1.1.67 | -999 |
- |
the median activity of TPMT is 44.7 ng/ml/h |
684733 |
| 2.1.1.67 | -999 |
- |
thiopurine methyltransferase levels above 23 nmol 6-methylthioguanine/g Hb per h indicates normal enzyme activity |
690115 |
| 2.1.1.67 | -999 |
- |
TPMT activity amongst 253 healthy Estonian volunteers varies from 21.5 ng/ml/h to 185.5 ng/ml/h with a median of 86.24 ng/ml/h |
686157 |
| 2.1.1.67 | -999 |
- |
TPMT activity of 0.5% of the patients is low, less than 5 U/ml RBC, for 11.9% intermediate, 5-13.7 U/ml RBC, and for 87.6% high, greater than 13.7 U/ml RBC |
686326 |
| 2.1.1.67 | 0.00000716 |
- |
TMPT reference activity after recovery of the bone marrow suppression |
690118 |
| 2.1.1.67 | 0.00003033 |
- |
elevated TPMT activity during the recovery phase of a bone marrow suppression, following the pancytopenic period |
690118 |
