EC Number   |
Source Tissue |
Reference |
|---|
   3.1.4.54 | brain |
- |
-, 707099, 707471, 708501, 708982, 710115, 714338, 714339, 749965 |
| 3.1.4.54 | brain |
a large degree of colocalization between transient receptor potential vanilloid type 1 and NAPE-PLD or fatty acid amide hydrolase, cycloxygenase-2, 12-lipoxygenase and catechol-O-methyltransferase is found in the hippocampal pyramidal neurons of the CA3 area of the Ammonยs horn and (with the exception of 12-lipoxyghenase) in some Purkinje cells |
710111 |
| 3.1.4.54 | brain |
activity detected in almost all of the mouse organs, with higher specific activities in brain, kidney, and testis |
708079 |
| 3.1.4.54 | brain |
distribution of NAPE-PLD in various brain regions and its age-dependent expression |
709610 |
| 3.1.4.54 | brain |
NAPE-PLD is expressed by specific populations of neurons in the brain and targeted to axonal processes. In the dentate gyrus a strong mRNA signal is detected in granule cells. Immunocytochemical analysis reveales intense NAPE-PLD immunoreactivity in the axons of granule cells (mossy fibers) and in axons of the vomeronasal nerve that project to the accessory olfactory bulb. NAPE-PLD expression is detected in hippocampus, cortex, thalamus, hypothalamus, but the intensity of immunostaining is weaker than in mossy fibers |
681093 |
| 3.1.4.54 | brain |
the enzyme concentrated presynaptically in several types of hippocampal excitatory axon terminals. Localized predominantly on the intracellular membrane cisternae of axonal calcium stores. The highest density of NAPE-PLD is found in mossy terminals of granule cells, which do not express CB1 receptors |
709629 |
| 3.1.4.54 | brain |
widely distributed in various brain regions of rat, with the highest activity in the brain stem. The enzyme activity in rat brain changes during development, and infant rats show a several-fold higher activity than adult rats |
708079 |
| 3.1.4.54 | brain |
widely distributed with higher specific activities in brain, kidney and testis |
666213 |
| 3.1.4.54 | BV-2 cell |
- |
750480 |
| 3.1.4.54 | cerebellar cortex |
- |
710111 |
