EC Number   |
Source Tissue |
Reference |
|---|
   3.1.3.75 | adipose tissue |
low expression, 3.38fold higher than in liver |
680993 |
| 3.1.3.75 | adult |
mineralization by PHOSPHO1 in medullary bone |
678951 |
| 3.1.3.75 | ameloblast |
presence in the enamel layer, ameloblast Tomes' processes, and in the walls of ameloblast secretory vesicles |
750663 |
| 3.1.3.75 | B-cell |
expression of PHOSPHO1 |
657232 |
| 3.1.3.75 | bone |
- |
-, 714633, 715704 |
| 3.1.3.75 | bone |
from 3 weeks old male chickens, from tibia, diaphyseal cortical and trabecular bone, expression pattern, PHOSPHO1 is specifically expressed at sites of mineralization in bone and cartilage |
655132 |
| 3.1.3.75 | bone |
high levels in matrix vesicles from growth plate chondrocytes |
678951 |
| 3.1.3.75 | bone |
matrix vesicles |
680993 |
| 3.1.3.75 | bone |
PHOSPHO1 is restricted to mineralizing regions of bone and growth plate. 120fold higher level of PHOSPHO1 expression in bone compared with liver. Enzyme present within matrix vesicles is in an active state. Present in early hypertrophic chondrocytes of the growth plate, and in osteoblasts of trabecular surfaces and infilling primary osteons of cortical bone |
680993 |
| 3.1.3.75 | brain |
expression of PHOSPHO1 |
657232 |
