EC Number |
Source Tissue |
Reference |
---|
2.7.1.30 | A-549 cell |
lung cell line |
660906 |
2.7.1.30 | adipocyte |
There is no difference in glycerol mRNA level between control 3T3-L1 adipocytes and 3T3-L1 Aqp7-RNAi transfected adipocytes, whereas a 4fold enzymatic activation of glycerol kinase is observable in Aqp7 knockout adipocytes (activity assay: 50 mM TrisHCl, pH 7.2, 5 mM ATP, 10 mM MgCl2, 100 mM KCl, 2.5 mM DTT, 4 mM glycerol, 500 microM 3H-glycerol, for 90 min at 37°C). |
682503 |
2.7.1.30 | adipose |
glycerol kinase mRNA tends to increase by 2.5fold in the mesenteric fat from Otsuka Long-Evans Tokushima Fatty rats compared to Long-Evans Tokushima Otsuka rats. A small increase in glycerol kinase mRNA expression is detected in the epididymal fat from Otsuka Long-Evans Tokushima Fatty rats compared with Long-Evans Tokushima Otsuka rats (124.5%). Rosiglitazone treatment markebly increases glycerol kinase mRNA expression in both the mesenteric and epididymal adipose tissues (1085.9% and 523.8% of the abundance in Long-Evans Tokushima Otsuka rats, respectively). The magnitude of glycerol kinase induced by rosiglitazone is significantly greater in the mesenteric fat than in the epididymal fat. |
681755 |
2.7.1.30 | adipose |
There is no difference in the mRNA levels and activities of adipose glycerol kinase between Aqp7-/- and Aqp7+/+ mice at 10 weeks of age. Adipose glycerol kinase activity of Aqp7-/- mice is significantly higher than that of wild type mice under the 12 h fasting state. The fat pads of the Aqp7-/- knockout mice are significantily larger than those of wild type mice at 20 weeks of age. |
682503 |
2.7.1.30 | adipose tissue |
- |
641287, 641299 |
2.7.1.30 | adipose tissue |
white and brown |
641287 |
2.7.1.30 | adult stem cell |
SS6-2 cell, stem cells from fat with myotube characteristics |
660906 |
2.7.1.30 | blood |
- |
721260 |
2.7.1.30 | blood plasma |
Aqp7-/- knockout mice have significantly lower plasma glycerol level under 12 h fasting conditions. |
682503 |
2.7.1.30 | brain |
- |
721260 |