EC Number   |
Source Tissue |
Reference |
|---|
   2.1.1.6 | adrenal gland |
- |
657526 |
| 2.1.1.6 | aorta |
- |
686194 |
| 2.1.1.6 | bladder |
- |
720288 |
| 2.1.1.6 | blood |
mononuclear cell |
441544 |
| 2.1.1.6 | brain |
- |
441507, 441508, 441514, 441524, 441534, 441536, 441543, 686194, 702948, 720288, 734783 |
| 2.1.1.6 | brain |
catechol-O-methyltransferase Val158Met modulation of prefrontal-parietal-striatal brain systems during arithmetic and temporal transformations in working memory |
688539 |
| 2.1.1.6 | brain |
COMT is not present in presynaptic dopaminergic and noradrenergic neurons |
735089 |
| 2.1.1.6 | brain |
COMT Val158Met polymorphism is related to structural brain differences in healthy adults. Val158 allele homozygotes exhibit significantly smaller temporal lobe and hippocampal volumes, with a trend for smaller amygdala volumes |
689231 |
| 2.1.1.6 | brain |
genetic variations of COMT can contribute to brain morphological abnormalities described in early phases of schizophrenia. Low-activity allele of catechol-O-methyltransferase is associated with increased lateral ventricles in patients with first episode non-affective psychosis |
689830 |
| 2.1.1.6 | brain |
highest activity in hippocampus. In all brain areas membrane-bound enzyme activity is lower than soluble enzyme activity |
657525 |
