EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.188 | prostaglandin-F synthase |
vascular smooth muscle cell |
- |
725083 |
1.1.1.21 | aldose reductase |
vascular smooth muscle cell |
- |
697639, 711859 |
1.10.5.1 | ribosyldihydronicotinamide dehydrogenase (quinone) |
vascular smooth muscle cell |
suppression of vascular smooth muscle cell proliferation mediated by resveratrol correlates with vascular smooth muscle cell downregulation |
697413 |
1.13.11.31 | arachidonate 12-lipoxygenase |
vascular smooth muscle cell |
- |
727969, 742456 |
1.13.11.33 | arachidonate 15-lipoxygenase |
vascular smooth muscle cell |
- |
-, 742845 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
vascular smooth muscle cell |
- |
686599 |
1.14.15.18 | calcidiol 1-monooxygenase |
vascular smooth muscle cell |
- |
658460 |
1.14.99.66 | [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase |
vascular smooth muscle cell |
- |
697355 |
1.17.3.2 | xanthine oxidase |
vascular smooth muscle cell |
- |
744635 |
1.3.1.72 | DELTA24-sterol reductase |
vascular smooth muscle cell |
- |
763004 |
1.4.3.13 | protein-lysine 6-oxidase |
vascular smooth muscle cell |
- |
685981, 686904, 687919, 695968, 699875 |
1.4.3.21 | primary-amine oxidase |
vascular smooth muscle cell |
- |
701561 |
1.6.2.2 | cytochrome-b5 reductase |
vascular smooth muscle cell |
- |
742308 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
vascular smooth muscle cell |
- |
724778 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
vascular smooth muscle cell |
primary cells. Glucose-mediated decreases in protein kinase G-I levels are inhibited by superoxide scavenger tempol or NAD(P)H oxidase inhibitors diphenylene iodonium or apocynin. High glucose exposure time-dependently increases superoxide production, which is abolished by tempol or apocynin treatment, but not by L-NAME, rotenone, or oxypurinol.Total protein levels and phosphorylated levels of subunit p47phox are increased after high glucose exposure. Transfection of cells with siRNA-p47phox abolishes glucose-induced superoxide production and restores protein kinase G-I protein levels |
686862 |
1.6.5.10 | NADPH dehydrogenase (quinone) |
vascular smooth muscle cell |
- |
699999 |
1.8.4.11 | peptide-methionine (S)-S-oxide reductase |
vascular smooth muscle cell |
splice variant msrA2a. Multiple MSRA variants participate in the repair of oxidized proteins in vascular smooth muscle cells mitochondria |
686891 |
2.4.1.212 | hyaluronan synthase |
vascular smooth muscle cell |
- |
695183, 759705 |
2.4.2.1 | purine-nucleoside phosphorylase |
vascular smooth muscle cell |
- |
-, 760109 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
vascular smooth muscle cell |
- |
680749 |
2.7.1.107 | diacylglycerol kinase (ATP) |
vascular smooth muscle cell |
- |
703112 |
2.7.1.137 | phosphatidylinositol 3-kinase |
vascular smooth muscle cell |
- |
708681 |
2.7.1.137 | phosphatidylinositol 3-kinase |
vascular smooth muscle cell |
activation of PI3K signaling is required for the inhibitory effect of Axl on mineral deposition |
686112 |
2.7.10.1 | receptor protein-tyrosine kinase |
vascular smooth muscle cell |
- |
672957 |
2.7.10.2 | non-specific protein-tyrosine kinase |
vascular smooth muscle cell |
PYK2 |
673110 |
2.7.11.12 | cGMP-dependent protein kinase |
vascular smooth muscle cell |
both PKG-Ialpha and PKG-Ibeta |
721982 |
2.7.11.12 | cGMP-dependent protein kinase |
vascular smooth muscle cell |
from normal/hypertensive fetal lambs |
721982 |
2.7.11.12 | cGMP-dependent protein kinase |
vascular smooth muscle cell |
from old and young rat aorta |
721982 |
2.7.11.12 | cGMP-dependent protein kinase |
vascular smooth muscle cell |
neointimal |
721982 |
2.7.11.12 | cGMP-dependent protein kinase |
vascular smooth muscle cell |
VCSM |
701630 |
2.7.11.12 | cGMP-dependent protein kinase |
vascular smooth muscle cell |
VSMC |
704619 |
2.7.11.15 | beta-adrenergic-receptor kinase |
vascular smooth muscle cell |
- |
738016 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
vascular smooth muscle cell |
i.e. VSM cell, aortic, primary, isozymes CaMKIIgammaB, CaMKIIgammaC, and CaMKIIdelta2, expression analysis, overview |
671227 |
2.7.11.18 | myosin-light-chain kinase |
vascular smooth muscle cell |
- |
-, 707035, 740289 |
2.7.11.2 | [pyruvate dehydrogenase (acetyl-transferring)] kinase |
vascular smooth muscle cell |
- |
739664 |
2.7.11.20 | elongation factor 2 kinase |
vascular smooth muscle cell |
- |
-, 739836 |
2.7.11.22 | cyclin-dependent kinase |
vascular smooth muscle cell |
- |
708842 |
2.7.11.24 | mitogen-activated protein kinase |
vascular smooth muscle cell |
obtained from thoracic aorta |
703567 |
2.7.12.2 | mitogen-activated protein kinase kinase |
vascular smooth muscle cell |
aortic, cell culture |
663988 |
3.1.1.6 | acetylesterase |
vascular smooth muscle cell |
kidney, cytochemistry and confocal microscopy |
696095 |
3.1.3.16 | protein-serine/threonine phosphatase |
vascular smooth muscle cell |
- |
708398 |
3.1.3.48 | protein-tyrosine-phosphatase |
vascular smooth muscle cell |
- |
692217 |
3.1.3.5 | 5'-nucleotidase |
vascular smooth muscle cell |
- |
681894 |
3.1.3.53 | [myosin-light-chain] phosphatase |
vascular smooth muscle cell |
- |
697357, 699755, 732145 |
3.1.4.1 | phosphodiesterase I |
vascular smooth muscle cell |
- |
713998, 750347 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
vascular smooth muscle cell |
- |
-, 715153 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
vascular smooth muscle cell |
enzyme isoform PDE1A is predominantly cytoplasmic in medial contractile vascular smoth muscle cell and nuclear in neointimal synthetic vascular smoth muscle cell |
679248 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
vascular smooth muscle cell |
- |
-, 711920, 715153 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
vascular smooth muscle cell |
phosphodiesterase 5 |
668864 |
3.1.4.37 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase |
vascular smooth muscle cell |
- |
728939 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
vascular smooth muscle cell |
- |
686114 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
vascular smooth muscle cell |
numerous PDE4D gene-derived variants including PDE4D3, PDE4D5, PDE4D7, PDE4D8, and PDE4D9 |
686114 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
vascular smooth muscle cell |
- |
707391 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
vascular smooth muscle cell |
mRNA and protein expression, expressed in vascular smooth muscle cells in atherosclerotic lesions from human carotid arteries |
677876 |
3.4.21.27 | coagulation factor XIa |
vascular smooth muscle cell |
- |
752439 |
3.4.21.5 | thrombin |
vascular smooth muscle cell |
- |
717167, 717797 |
3.4.21.6 | coagulation factor Xa |
vascular smooth muscle cell |
- |
731588 |
3.4.21.75 | Furin |
vascular smooth muscle cell |
- |
667391, 708682 |
3.4.21.B1 | hyaluronan-binding serine protease |
vascular smooth muscle cell |
- |
690121 |
3.4.21.B26 | proprotein convertase 5 |
vascular smooth muscle cell |
- |
673108, 675490 |
3.4.21.B26 | proprotein convertase 5 |
vascular smooth muscle cell |
up-regulation of PC5 in proliferating cell nuclear antigen-positive vascular smooth muscle cells following balloon injury |
675490 |
3.4.22.27 | cathepsin S |
vascular smooth muscle cell |
- |
733448 |
3.4.22.56 | caspase-3 |
vascular smooth muscle cell |
from umbilical cord |
695963 |
3.4.24.22 | stromelysin 2 |
vascular smooth muscle cell |
- |
717202 |
3.4.24.23 | matrilysin |
vascular smooth muscle cell |
- |
-, 683742, 708021 |
3.4.24.35 | gelatinase B |
vascular smooth muscle cell |
- |
683111, 697149, 701317, 708188 |
3.4.24.7 | interstitial collagenase |
vascular smooth muscle cell |
- |
701317 |
3.5.3.1 | arginase |
vascular smooth muscle cell |
- |
697211 |
3.6.5.2 | small monomeric GTPase |
vascular smooth muscle cell |
- |
735277 |
4.1.1.17 | ornithine decarboxylase |
vascular smooth muscle cell |
- |
695461 |
4.4.1.1 | cystathionine gamma-lyase |
vascular smooth muscle cell |
- |
707176, 708133 |
4.4.1.1 | cystathionine gamma-lyase |
vascular smooth muscle cell |
mainly expressed in airway and vascular smooth muscle cells in rat lung tissue |
691972 |
4.6.1.1 | adenylate cyclase |
vascular smooth muscle cell |
- |
690360, 707057 |
4.6.1.2 | guanylate cyclase |
vascular smooth muscle cell |
- |
653601, 707919 |
5.3.4.1 | protein disulfide-isomerase |
vascular smooth muscle cell |
- |
727921 |
5.3.99.2 | Prostaglandin-D synthase |
vascular smooth muscle cell |
- |
660668, 682619 |
5.3.99.3 | prostaglandin-E synthase |
vascular smooth muscle cell |
cells express both microsomal isoforms mPGES-1 and mPGES-2 and cytosolic isoform cPGES |
681664 |
5.3.99.3 | prostaglandin-E synthase |
vascular smooth muscle cell |
cells express both microsomal isoforms mPGES-1 and mPGES-2 and cytosolic isoform cPGES. Isoform mPGES-1 contributes most to total activity and is induced by interleukin IL-1beta, which in turn reduces the ability of cells to produce prostaglandin I2 |
681664 |
5.3.99.4 | prostaglandin-I synthase |
vascular smooth muscle cell |
- |
660924 |
5.3.99.5 | thromboxane-A synthase |
vascular smooth muscle cell |
- |
714914 |
5.6.1.6 | channel-conductance-controlling ATPase |
vascular smooth muscle cell |
- |
675622 |
7.2.2.10 | P-type Ca2+ transporter |
vascular smooth muscle cell |
- |
734295 |
7.2.2.8 | P-type Cu+ transporter |
vascular smooth muscle cell |
- |
749535, 749770 |
7.2.2.9 | P-type Cu2+ transporter |
vascular smooth muscle cell |
- |
668543 |
7.3.2.1 | ABC-type phosphate transporter |
vascular smooth muscle cell |
expression of Pit-1 and Pit-2, Pit-1 is not a component of matrix vesicles or apoptotic bodies, expression analysis, Pit-1 is the predominant sodium-dependent phosphate cotransporter, overview |
686123 |