EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.105 | all-trans-retinol dehydrogenase (NAD+) |
submandibular gland |
strong mRNA expression |
692959 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
submandibular gland |
- |
673845 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
submandibular gland |
- |
665457 |
1.14.18.2 | CMP-N-acetylneuraminate monooxygenase |
submandibular gland |
- |
639313, 639318, 639319, 639329, 639333 |
1.8.5.1 | glutathione dehydrogenase (ascorbate) |
submandibular gland |
- |
394033 |
2.1.1.20 | glycine N-methyltransferase |
submandibular gland |
- |
704524 |
2.1.1.4 | acetylserotonin O-methyltransferase |
submandibular gland |
- |
719578 |
2.3.1.25 | plasmalogen synthase |
submandibular gland |
- |
486673 |
2.3.1.44 | N-acetylneuraminate 4-O-acetyltransferase |
submandibular gland |
- |
487031 |
2.3.1.45 | N-acetylneuraminate 7-O(or 9-O)-acetyltransferase |
submandibular gland |
- |
487037, 487038, 487042, 672480, 677235, 686986, 94411 |
2.4.1.40 | glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase |
submandibular gland |
A-type enzyme expression |
658843 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
submandibular gland |
- |
659136 |
2.4.3.2 | beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3-sialyltransferase |
submandibular gland |
- |
745249 |
2.4.3.4 | beta-galactoside alpha-2,3-sialyltransferase |
submandibular gland |
- |
745248, 745249, 745253 |
2.6.1.42 | branched-chain-amino-acid transaminase |
submandibular gland |
- |
640008 |
2.7.1.11 | 6-phosphofructokinase |
submandibular gland |
- |
640524 |
2.7.1.68 | 1-phosphatidylinositol-4-phosphate 5-kinase |
submandibular gland |
lowest expression |
759416 |
2.7.11.22 | cyclin-dependent kinase |
submandibular gland |
p58 expression is elevated between day 14 and day 16 post coitus |
491507 |
2.7.7.43 | N-acylneuraminate cytidylyltransferase |
submandibular gland |
- |
645262, 645264 |
2.7.7.9 | UTP-glucose-1-phosphate uridylyltransferase |
submandibular gland |
- |
643728 |
2.7.8.15 | UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase |
submandibular gland |
- |
645359 |
2.8.2.20 | protein-tyrosine sulfotransferase |
submandibular gland |
- |
676996 |
3.1.2.2 | palmitoyl-CoA hydrolase |
submandibular gland |
- |
646135, 646169 |
3.1.2.20 | acyl-CoA hydrolase |
submandibular gland |
- |
646135, 646169 |
3.1.21.1 | deoxyribonuclease I |
submandibular gland |
- |
664154 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
submandibular gland |
- |
649518, 668968 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
submandibular gland |
acinar epithelial cell |
649519 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
submandibular gland |
PDE1 is present in young and adult gland |
649520 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
submandibular gland |
PDE2 is present in young gland, not in adult |
649520 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
submandibular gland |
PDE3 is present in young and adult gland |
649520 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
submandibular gland |
PDE5 is present in young and adult gland |
649520 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
submandibular gland |
- |
689817 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
submandibular gland |
PDE4 is present in young and adult gland. During development PDE4 is the major PDE |
649520 |
3.1.6.8 | cerebroside-sulfatase |
submandibular gland |
- |
650885 |
3.1.6.8 | cerebroside-sulfatase |
submandibular gland |
oral cavity treatment with 7,12-dimethylbenzanthrracene increases activity significantly in both sexes. Administration of 7,12-dimethylbenzanthracene plus beta-carotene decreases activity slightly |
650885 |
3.1.8.1 | aryldialkylphosphatase |
submandibular gland |
acini of the submandibular gland, PON1 |
692441 |
3.2.1.22 | alpha-galactosidase |
submandibular gland |
- |
171251 |
3.3.2.9 | microsomal epoxide hydrolase |
submandibular gland |
- |
208880, 208881 |
3.4.14.2 | dipeptidyl-peptidase II |
submandibular gland |
- |
95240 |
3.4.14.5 | dipeptidyl-peptidase IV |
submandibular gland |
- |
36235 |
3.4.19.3 | pyroglutamyl-peptidase I |
submandibular gland |
- |
95298 |
3.4.21.117 | stratum corneum chymotryptic enzyme |
submandibular gland |
- |
647331 |
3.4.21.119 | kallikrein 13 |
submandibular gland |
- |
647359, 647370, 647371, 669178, 669519 |
3.4.21.119 | kallikrein 13 |
submandibular gland |
enzyme regulation is parallel and similar to that of renin |
647369 |
3.4.21.119 | kallikrein 13 |
submandibular gland |
highest activity |
647369 |
3.4.21.119 | kallikrein 13 |
submandibular gland |
larger amounts in male than female mice |
647369 |
3.4.21.26 | prolyl oligopeptidase |
submandibular gland |
- |
683344 |
3.4.21.35 | tissue kallikrein |
submandibular gland |
- |
647492, 647496, 647500, 647530, 668967, 669519, 710169 |
3.4.21.54 | gamma-Renin |
submandibular gland |
- |
29366 |
3.4.21.77 | semenogelase |
submandibular gland |
- |
395498 |
3.4.21.B25 | PACE4 proprotein convertase |
submandibular gland |
- |
679429, 718024 |
3.4.21.B25 | PACE4 proprotein convertase |
submandibular gland |
PACE4 is intensely expressed in the submandibular epithelium-derived cells including proacinar, terminal tubular, and presumptive ductal cells in the prenatal submandibular gland |
709485 |
3.4.21.B40 | kallikrein 9 |
submandibular gland |
- |
647359, 668778 |
3.4.21.B41 | kallikrein 10 |
submandibular gland |
- |
647361 |
3.4.22.52 | calpain-1 |
submandibular gland |
- |
643983, 643984 |
3.4.22.52 | calpain-1 |
submandibular gland |
the large catalytic subunits of calpains 1 and the small regulatory subunit common to calpains 1 and 2 are weakly expressed in the parotid gland, sublingual gland, and submandibular gland at similar levels in males and females |
752607 |
3.4.22.53 | calpain-2 |
submandibular gland |
- |
643989 |
3.4.22.53 | calpain-2 |
submandibular gland |
the large catalytic subunits of calpains 2 and the small regulatory subunit common to calpains 1 and 2 are weakly expressed in the parotid gland, sublingual gland, and submandibular gland at similar levels in males and females |
752607 |
3.4.22.54 | calpain-3 |
submandibular gland |
the single large catalytic subunit of calpain 3 is expressed predominantly in the submandibular gland at markedly higher levels in males than in females and in a manner dependent on androgens. In granular convoluted tubule cell calpain 3 immunoreactivity is localized predominantly in the cytosolic region and is absent in the secretory granules. Granular convoluted tubule is the primary site of production of calpain 3 submandibular gland |
752607 |
3.4.22.56 | caspase-3 |
submandibular gland |
- |
695951 |
3.4.22.64 | caspase-11 |
submandibular gland |
- |
698218 |
3.4.23.15 | renin |
submandibular gland |
- |
29366, 95756, 95765, 95770, 95775, 95776, 95777, 95795, 95798 |
3.4.23.15 | renin |
submandibular gland |
enzyme activity is increased in hypertensive mice compared to wild-type mice |
667384 |
3.6.1.9 | nucleotide diphosphatase |
submandibular gland |
- |
711034 |
3.6.5.2 | small monomeric GTPase |
submandibular gland |
Rac1 appears to be important for parenchyma expansion at the beginning of cytodifferentiation, while RhoC, Cdc42 and the inactive phosphorylated form of Rac1 seemed associated with lumen formation and cell polarization in terminal tubules in the developing submandilbular gland |
699621 |
4.2.1.1 | carbonic anhydrase |
submandibular gland |
carbonic anhydrase XIII |
679413 |
4.3.2.3 | ureidoglycolate lyase |
submandibular gland |
- |
34477, 34478 |
5.1.3.7 | UDP-N-acetylglucosamine 4-epimerase |
submandibular gland |
- |
2412 |
5.4.2.3 | phosphoacetylglucosamine mutase |
submandibular gland |
- |
3296, 3300, 3302 |
7.2.2.13 | Na+/K+-exchanging ATPase |
submandibular gland |
- |
246966 |