EC Number   |
Recommended Name   |
Source Tissue   |
Reference   |
|---|
  1.1.1.102 | 3-dehydrosphinganine reductase |
small intestine |
high expression |
656256 |
  1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
small intestine |
- |
-, 669380, 670691 |
1.1.1.172 | 2-oxoadipate reductase |
small intestine |
- |
286113 |
  1.1.1.188 | prostaglandin-F synthase |
small intestine |
low activity |
687797 |
  1.1.1.188 | prostaglandin-F synthase |
small intestine |
low expression level |
760437 |
  1.1.1.21 | aldose reductase |
small intestine |
- |
697266 |
  1.1.1.218 | morphine 6-dehydrogenase |
small intestine |
in male hamsters |
740637 |
 1.1.1.22 | UDP-glucose 6-dehydrogenase |
small intestine |
- |
286303 |
 1.1.1.23 | histidinol dehydrogenase |
small intestine |
very low activity |
656358 |
  1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
small intestine |
high expression level of AKR1C28 |
739953 |
  1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
small intestine |
in male hamsters |
740637 |
  1.1.1.270 | 3beta-hydroxysteroid 3-dehydrogenase |
small intestine |
- |
724124 |
1.1.1.278 | 3beta-hydroxy-5alpha-steroid dehydrogenase |
small intestine |
- |
639086 |
 1.1.1.315 | 11-cis-retinol dehydrogenase |
small intestine |
39% mRNA expression of Rdh5 compared to liver |
690797 |
 1.1.1.315 | 11-cis-retinol dehydrogenase |
small intestine |
low mRNA expression |
692939 |
 1.1.1.315 | 11-cis-retinol dehydrogenase |
small intestine |
the 3 kb isoform is the most abundant one |
692332 |
  1.1.1.34 | hydroxymethylglutaryl-CoA reductase (NADPH) |
small intestine |
- |
286567 |
  1.1.1.34 | hydroxymethylglutaryl-CoA reductase (NADPH) |
small intestine |
low expression level |
722328 |
  1.1.1.41 | isocitrate dehydrogenase (NAD+) |
small intestine |
- |
741458 |
  1.1.1.44 | phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) |
small intestine |
- |
670806 |
  1.1.1.49 | glucose-6-phosphate dehydrogenase (NADP+) |
small intestine |
- |
657284 |
 1.1.1.50 | 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) |
small intestine |
- |
389547 |
  1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
small intestine |
in female hamsters |
740637 |
 1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
small intestine |
- |
688956 |
 1.1.1.71 | alcohol dehydrogenase [NAD(P)+] |
small intestine |
- |
668112 |
 1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
small intestine |
- |
285953 |
 1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
small intestine |
high level of expression and activity |
695148 |
 1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
small intestine |
- |
671327 |
 1.11.1.7 | peroxidase |
small intestine |
- |
439761, 698048 |
  1.11.1.9 | glutathione peroxidase |
small intestine |
- |
685921 |
  1.11.1.9 | glutathione peroxidase |
small intestine |
weak expression of pGPx |
672988 |
  1.13.11.11 | tryptophan 2,3-dioxygenase |
small intestine |
- |
743358 |
 1.13.11.17 | indole 2,3-dioxygenase |
small intestine |
activity is present in relevant amounts even in newborn rats. The specific activity increases significantly in young rats by about 44% in comparison to newborns |
673130 |
  1.13.11.20 | cysteine dioxygenase |
small intestine |
detectable levels |
439556 |
  1.13.11.31 | arachidonate 12-lipoxygenase |
small intestine |
- |
395410 |
  1.13.11.5 | homogentisate 1,2-dioxygenase |
small intestine |
- |
439387 |
  1.13.11.52 | indoleamine 2,3-dioxygenase |
small intestine |
- |
395457, 395458, 395461, 395462, 395466, 395474, 663995, 663996, 665459, 666895, 671714, 743358 |
  1.13.11.52 | indoleamine 2,3-dioxygenase |
small intestine |
in newborn rats IDO activity is present only in small intestine. In the group of rats aged 2-3 months, the highest specific activity is found in the small intestine, decrease of enzyme activity in relation to age |
674079 |
  1.13.11.52 | indoleamine 2,3-dioxygenase |
small intestine |
indoleamine 2,3-dioxygenase |
395466 |
 1.13.11.63 | beta-carotene 15,15'-dioxygenase |
small intestine |
- |
438231, 438241, 695441, 728342 |
 1.13.11.63 | beta-carotene 15,15'-dioxygenase |
small intestine |
mucosa |
438238 |
 1.13.11.71 | carotenoid-9',10'-cleaving dioxygenase |
small intestine |
- |
719806 |
 1.13.11.71 | carotenoid-9',10'-cleaving dioxygenase |
small intestine |
mucosa of small intestine |
720152 |
  1.14.13.8 | flavin-containing monooxygenase |
small intestine |
- |
673290, 690175 |
  1.14.13.9 | kynurenine 3-monooxygenase |
small intestine |
- |
673130 |
  1.14.14.1 | unspecific monooxygenase |
small intestine |
CYP4A7 |
660409 |
  1.14.14.154 | sterol 14alpha-demethylase |
small intestine |
- |
673147 |
  1.14.14.18 | heme oxygenase (biliverdin-producing) |
small intestine |
- |
674063 |
  1.14.14.23 | cholesterol 7alpha-monooxygenase |
small intestine |
- |
712117 |
 1.14.14.29 | 25/26-hydroxycholesterol 7alpha-hydroxylase |
small intestine |
- |
659660 |
 1.14.14.73 | albendazole monooxygenase (sulfoxide-forming) |
small intestine |
- |
767389 |
1.14.14.74 | albendazole monooxygenase (hydroxylating) |
small intestine |
- |
767389 |
1.14.14.B9 | fatty acid omega2/3-hydroxyase |
small intestine |
isoforms CYP4F2/3, CYP4F11 and CYP4F12 vary 2.4- to 9.7fold, representing 36.4, 2.4 and 9.3% of total immunoquantified CYP1-4 proteins, respectively. CYP4F is the most abundant P450 subfamily in small intestines |
746558 |
  1.14.15.15 | cholestanetriol 26-monooxygenase |
small intestine |
- |
736710 |
  1.14.15.15 | cholestanetriol 26-monooxygenase |
small intestine |
truncated enzyme form |
671685 |
  1.14.15.18 | calcidiol 1-monooxygenase |
small intestine |
truncated enzyme form |
671685 |
  1.14.15.3 | alkane 1-monooxygenase |
small intestine |
- |
285377 |
 1.14.16.5 | alkylglycerol monooxygenase |
small intestine |
- |
688220 |
  1.14.17.1 | dopamine beta-monooxygenase |
small intestine |
- |
727633 |
 1.14.18.2 | CMP-N-acetylneuraminate monooxygenase |
small intestine |
- |
639329 |
 1.14.18.2 | CMP-N-acetylneuraminate monooxygenase |
small intestine |
no significant temporal alterations in the activity in foetal and newborn small intestine. Birth is followed by a 2-8fold decrease in activity, depending on the region of the small intestine. Increase in activity from duodenum to ileum |
639336 |
  1.14.19.1 | stearoyl-CoA 9-desaturase |
small intestine |
- |
767001 |
  1.14.19.20 | DELTA7-sterol 5(6)-desaturase |
small intestine |
mRNA expression |
390941 |
 1.14.99.38 | cholesterol 25-monooxygenase |
small intestine |
- |
700999 |
  1.17.1.4 | xanthine dehydrogenase |
small intestine |
- |
644558 |
 1.17.3.2 | xanthine oxidase |
small intestine |
- |
690202 |
 1.2.1.18 | malonate-semialdehyde dehydrogenase (acetylating) |
small intestine |
- |
690142 |
  1.2.1.25 | branched-chain alpha-keto acid dehydrogenase system |
small intestine |
- |
762596 |
  1.2.1.3 | aldehyde dehydrogenase (NAD+) |
small intestine |
- |
690142 |
  1.2.1.3 | aldehyde dehydrogenase (NAD+) |
small intestine |
isozyme Aldh1b1 mRNA expression is highest in small intestine |
690142 |
  1.2.1.31 | L-aminoadipate-semialdehyde dehydrogenase |
small intestine |
- |
288202, 675897, 690142 |
  1.2.1.31 | L-aminoadipate-semialdehyde dehydrogenase |
small intestine |
mRNA expression |
675897 |
 1.2.1.36 | retinal dehydrogenase |
small intestine |
- |
690142 |
  1.2.1.41 | glutamate-5-semialdehyde dehydrogenase |
small intestine |
isozyme Aldh4a1 mRNA expression is highest in small intestine |
690142 |
  1.2.1.47 | 4-trimethylammoniobutyraldehyde dehydrogenase |
small intestine |
- |
690142 |
  1.2.1.5 | aldehyde dehydrogenase [NAD(P)+] |
small intestine |
- |
690142 |
  1.2.1.8 | betaine-aldehyde dehydrogenase |
small intestine |
- |
390346 |
 1.2.1.84 | alcohol-forming fatty acyl-CoA reductase (NADPH) |
small intestine |
- |
656242 |
 1.2.1.84 | alcohol-forming fatty acyl-CoA reductase (NADPH) |
small intestine |
most abundant in |
656242 |
  1.2.1.88 | L-glutamate gamma-semialdehyde dehydrogenase |
small intestine |
short isoform |
701646 |
 1.2.3.1 | aldehyde oxidase |
small intestine |
- |
762957 |
 1.2.4.4 | 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) |
small intestine |
- |
710845 |
  1.3.1.38 | trans-2-enoyl-CoA reductase (NADPH) |
small intestine |
TER mRNA |
656193 |
  1.3.1.48 | 13,14-dehydro-15-oxoprostaglandin 13-reductase |
small intestine |
- |
390826 |
  1.3.3.4 | protoporphyrinogen oxidase |
small intestine |
- |
697205 |
 1.4.3.13 | protein-lysine 6-oxidase |
small intestine |
- |
391741, 659751 |
 1.4.3.13 | protein-lysine 6-oxidase |
small intestine |
high LOXL3-sv2 expression |
772166 |
  1.5.1.20 | methylenetetrahydrofolate reductase [NAD(P)H] |
small intestine |
- |
705297 |
  1.5.1.5 | methylenetetrahydrofolate dehydrogenase (NADP+) |
small intestine |
- |
734262 |
 1.6.2.4 | NADPH-hemoprotein reductase |
small intestine |
- |
725473 |
 1.6.2.4 | NADPH-hemoprotein reductase |
small intestine |
beta-naphtoflavone-treated animals |
-, 288607 |
 1.6.3.5 | renalase |
small intestine |
besides kidney, renalase gene expression is detectable in the heart, skeletal muscle, and the small intestine |
728036 |
  1.6.5.2 | NAD(P)H dehydrogenase (quinone) |
small intestine |
- |
394366, 694562 |
  1.7.1.7 | GMP reductase |
small intestine |
- |
659550 |
 1.8.1.9 | thioredoxin-disulfide reductase (NADPH) |
small intestine |
- |
658795 |
  1.8.3.1 | sulfite oxidase |
small intestine |
little expression |
657738 |
 1.8.3.2 | thiol oxidase |
small intestine |
- |
393057 |
 1.8.3.2 | thiol oxidase |
small intestine |
epithelium |
393048 |
  1.8.4.12 | peptide-methionine (R)-S-oxide reductase |
small intestine |
- |
711940 |
  1.8.4.12 | peptide-methionine (R)-S-oxide reductase |
small intestine |
isozyme MsrB3 |
669008 |