EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.40 | malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) |
semen |
- |
286714 |
1.1.1.42 | isocitrate dehydrogenase (NADP+) |
semen |
mainly localized to the principal piece of the porcine sperm flagellum |
760487 |
1.11.1.9 | glutathione peroxidase |
semen |
- |
677190, 690120 |
1.11.2.2 | myeloperoxidase |
semen |
- |
743774 |
1.2.1.12 | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) |
semen |
- |
763063 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
semen |
- |
668960 |
2.1.1.233 | [phosphatase 2A protein]-leucine-carboxy methyltransferase |
semen |
isolated from proximal caput, distal caput, and caudal regions of the epididymis |
758126 |
2.1.4.1 | glycine amidinotransferase |
semen |
- |
485975 |
2.3.1.16 | acetyl-CoA C-acyltransferase |
semen |
- |
486403 |
2.3.1.7 | carnitine O-acetyltransferase |
semen |
- |
487418 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
semen |
GALNTL5 gene expression is significantly higher in ejaculated sperm than in cauda epididymal sperm. GALNTL5 is strongly localized in the mid-piece and head of ejaculated sperm, and in the head-tail coupling apparatus and acrosome of cauda epididymal sperm. The amount of GALNTL5 protein in seminal plasma is significantly higher than in ejaculated sperm |
755794 |
2.4.2.31 | NAD+-protein-arginine ADP-ribosyltransferase |
semen |
- |
672357 |
2.7.1.1 | hexokinase |
semen |
- |
661740, 758656 |
2.7.1.1 | hexokinase |
semen |
sperm membrane and sperm extract, uncapacitated causal epididymal sperm, contains a unique tyrosine-phosphorylated form of hexokinase |
640229 |
2.7.1.30 | glycerol kinase |
semen |
- |
761751 |
2.7.11.11 | cAMP-dependent protein kinase |
semen |
- |
661558 |
2.7.8.27 | sphingomyelin synthase |
semen |
SMS2 mRNA levels are decreased by about 80.67, and protein levels are reduced to approximately 71.33 % in asthenospermia compared to normozoospermia |
761961 |
3.1.1.32 | phospholipase A1 |
semen |
seminal plasma, containing several phospholipase activities |
666690 |
3.1.1.4 | phospholipase A2 |
semen |
enzyme is secreted from sperm acrosomes |
751474 |
3.1.1.47 | 1-alkyl-2-acetylglycerophosphocholine esterase |
semen |
the activity is significantly and negatively correlated with sperm motility. Platelet-activating factor acetylhydrolase serves as a decapacitation factor |
679929 |
3.1.1.5 | lysophospholipase |
semen |
in vitro storage for 48 h does not affect activity |
666690 |
3.1.3.2 | acid phosphatase |
semen |
- |
134698, 134750 |
3.1.3.2 | acid phosphatase |
semen |
enzyme forms S4, S3, S2, and Szn are present in cytoplasmic droplets. Enzyme forms S4, S3, and Szn are present in reproductive tract particles. Enzyme form S4 and Szn are present in acrosomal extract and intact epididymal sperm. Heads and midpieces from fragmented epididymal sperm contain enzyme forms S4 and S3 and small amounts of S2, Szn and S1 |
134728 |
3.1.4.11 | phosphoinositide phospholipase C |
semen |
the gamma1 isoenzyme is restricted to the sperm head |
135130 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
semen |
- |
135368 |
3.1.6.8 | cerebroside-sulfatase |
semen |
- |
135690 |
3.1.8.1 | aryldialkylphosphatase |
semen |
- |
729353 |
3.2.1.35 | hyaluronoglucosaminidase |
semen |
- |
171410, 751311 |
3.2.1.35 | hyaluronoglucosaminidase |
semen |
soluble and acrosome-bound isoforms |
171397, 171406 |
3.2.1.51 | alpha-L-fucosidase |
semen |
- |
208699, 680897, 698301 |
3.2.1.51 | alpha-L-fucosidase |
semen |
one form tightly bound to the sperm plasma membrane, one form present in the gonad fluid |
208698 |
3.2.1.51 | alpha-L-fucosidase |
semen |
two isoforms: A, B, characterized during epididymal maturation |
208696 |
3.2.1.52 | beta-N-acetylhexosaminidase |
semen |
- |
393667, 393715 |
3.2.2.5 | NAD+ glycohydrolase |
semen |
- |
137055, 137060, 137076 |
3.4.11.1 | leucyl aminopeptidase |
semen |
- |
755065 |
3.4.11.3 | cystinyl aminopeptidase |
semen |
- |
35897 |
3.4.14.5 | dipeptidyl-peptidase IV |
semen |
- |
696136 |
3.4.15.1 | peptidyl-dipeptidase A |
semen |
- |
710612, 731136, 81211 |
3.4.15.1 | peptidyl-dipeptidase A |
semen |
seminal plasma |
81232, 81238, 81250, 81280 |
3.4.15.1 | peptidyl-dipeptidase A |
semen |
two distinct enzyme forms |
81269 |
3.4.17.10 | carboxypeptidase E |
semen |
- |
731936 |
3.4.17.3 | lysine carboxypeptidase |
semen |
- |
36402 |
3.4.19.3 | pyroglutamyl-peptidase I |
semen |
- |
708574 |
3.4.19.3 | pyroglutamyl-peptidase I |
semen |
highest level in particulate sperm fraction. Increased activity in necrozoospermia |
670862 |
3.4.21.10 | acrosin |
semen |
- |
36460, 36461, 36462, 36464, 36465, 36466, 36467, 36468, 36469, 36471, 36472, 36475, 36476, 36477, 36479, 36482, 36485, 36486, 36487, 36488, 668293, 668679, 668680, 668887, 692404, 753777, 755363, 755574 |
3.4.21.10 | acrosin |
semen |
compared to control, enzyme activity is significantly lower in patients with unexplained infertility but high sperm mobility and in patients with infertility and low sperm mobility |
668678 |
3.4.21.10 | acrosin |
semen |
from infertile men |
36483 |
3.4.21.109 | matriptase |
semen |
only matriptase-HAI-1 complexes and not latent matriptase are detected in urine and seminal fluid |
707054 |
3.4.21.26 | prolyl oligopeptidase |
semen |
- |
683344, 683389, 81331 |
3.4.21.35 | tissue kallikrein |
semen |
- |
647531 |
3.4.21.77 | semenogelase |
semen |
- |
647580, 647591, 666798, 681472, 696922, 718349 |
3.4.21.B12 | prostase |
semen |
seminal plasma, varying amounts of enzyme |
668285 |
3.4.21.B6 | prostasin |
semen |
- |
671251 |
3.4.22.15 | cathepsin L |
semen |
- |
647906 |
3.4.22.61 | caspase-8 |
semen |
- |
753880 |
3.4.22.62 | caspase-9 |
semen |
- |
753880 |
3.4.22.B32 | calpain 12 |
semen |
calpain 12 appears to be involved in the regulation of flagellar movement, but not in that of the acrosome reaction |
682812 |
3.4.23.3 | gastricsin |
semen |
- |
36847, 36864 |
3.4.24.23 | matrilysin |
semen |
presence of enzyme in plasma of normal and azoospermic semen |
668888 |
3.4.24.65 | macrophage elastase |
semen |
- |
733087 |
3.4.24.B11 | ADAMTS1 endopeptidase |
semen |
- |
755570 |
3.4.24.B12 | ADAMTS5 endopeptidase |
semen |
- |
755570 |
3.5.1.23 | ceramidase |
semen |
- |
755487 |
3.6.1.9 | nucleotide diphosphatase |
semen |
- |
246819 |
4.2.1.1 | carbonic anhydrase |
semen |
carbonic anhydrase XIII |
679413 |
4.6.1.1 | adenylate cyclase |
semen |
- |
34777, 34787 |
4.6.1.18 | pancreatic ribonuclease |
semen |
- |
691341, 729310 |
5.3.99.2 | Prostaglandin-D synthase |
semen |
determination of the correlation between content of enzyme in seminal plasma and on the surface of sperm |
678359 |
5.6.1.2 | dynein ATPase |
semen |
- |
247010, 247011, 247012, 247027 |