EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.105 | all-trans-retinol dehydrogenase (NAD+) |
prostate gland |
- |
697796 |
1.1.1.14 | L-iditol 2-dehydrogenase |
prostate gland |
ventral and dorsal |
285881 |
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
prostate gland |
androgen-sensitive cancer cells LNCaP and hormone-independent PC3 cells, enzyme expression is induced by steroids |
285939 |
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
prostate gland |
very low expression level |
669380 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
prostate gland |
- |
763756 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
prostate gland |
- |
668432, 699847, 761757 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
prostate gland |
presence of 11beta-hydroxysteroid dehydrogenase mRNA transcripts and protein in all tissues of the reproductive tract examined, but cortison-cortisol interconversion is undetectable in the corpus and cauda epididymides, vas deferens, vesicular and prostate glands |
695090 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
prostate gland |
20alpha-HSD mRNA lower expressed |
285997 |
1.1.1.188 | prostaglandin-F synthase |
prostate gland |
low expression level |
760437 |
1.1.1.209 | 3(or 17)alpha-hydroxysteroid dehydrogenase |
prostate gland |
- |
389547 |
1.1.1.213 | 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) |
prostate gland |
- |
347987, 668392, 676812 |
1.1.1.213 | 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) |
prostate gland |
epithelial cells, but not the stromal cells or endothelial cells |
688137 |
1.1.1.213 | 3alpha-hydroxysteroid 3-dehydrogenase (Re-specific) |
prostate gland |
in primary prostate stromal cells, co-localization with RODH like 3alpha/17beta-HSD, EC 1.1.1.239 |
676002 |
1.1.1.22 | UDP-glucose 6-dehydrogenase |
prostate gland |
increased UGDH expression in cancerous acini and decreased expression in normal-appearing acini of the same prostate relative to acini of non-cancerous prostates |
698331 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
prostate gland |
- |
287211, 287212 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
prostate gland |
androgen target tissues |
673341 |
1.1.1.300 | NADP-retinol dehydrogenase |
prostate gland |
- |
654687, 656064, 762061 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
prostate gland |
21% mRNA expression of Rdh5 compared to liver |
690797 |
1.1.1.357 | 3alpha-hydroxysteroid 3-dehydrogenase |
prostate gland |
- |
724711 |
1.1.1.50 | 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) |
prostate gland |
- |
389529, 389531, 389540, 389547, 389551 |
1.1.1.50 | 3alpha-hydroxysteroid 3-dehydrogenase (Si-specific) |
prostate gland |
epithelial cells, but not the stromal cells or endothelial cells |
688137 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
prostate gland |
isozyme 17beta-HSD5 |
675983 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
prostate gland |
- |
654934, 670033, 686263, 762074 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
prostate gland |
epithelial cells of the acini and stromal cells |
675190 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
prostate gland |
moderate expression |
685803 |
1.1.1.71 | alcohol dehydrogenase [NAD(P)+] |
prostate gland |
- |
655563 |
1.1.1.95 | phosphoglycerate dehydrogenase |
prostate gland |
- |
287528 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
prostate gland |
- |
285953, 699847 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
prostate gland |
presence of 11beta-hydroxysteroid dehydrogenase mRNA transcripts and protein in all tissues of the reproductive tract examined, but cortison-cortisol interconversion is undetectable in the corpus and cauda epididymides, vas deferens, vesicular and prostate glands |
695090 |
1.1.2.4 | D-lactate dehydrogenase (cytochrome) |
prostate gland |
- |
740447 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
prostate gland |
- |
671327 |
1.11.1.9 | glutathione peroxidase |
prostate gland |
- |
685952, 701039 |
1.11.1.9 | glutathione peroxidase |
prostate gland |
expression is observed in the membranes of vacuoles contained in prostate secretions as well as in the endothelium of arterioles and venules |
690120 |
1.13.11.33 | arachidonate 15-lipoxygenase |
prostate gland |
- |
659222, 674995, 676263 |
1.13.11.5 | homogentisate 1,2-dioxygenase |
prostate gland |
- |
439387 |
1.13.11.63 | beta-carotene 15,15'-dioxygenase |
prostate gland |
- |
713952 |
1.13.11.63 | beta-carotene 15,15'-dioxygenase |
prostate gland |
low levels of BCO mRNA |
438228 |
1.13.11.71 | carotenoid-9',10'-cleaving dioxygenase |
prostate gland |
prostate connective tissue |
720152 |
1.14.11.33 | DNA oxidative demethylase |
prostate gland |
high ABH3 mRNA levels |
723671 |
1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
prostate gland |
- |
754938 |
1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
prostate gland |
lysine-specific demethylase 1 colocalizes with androgen receptor |
670377 |
1.14.13.8 | flavin-containing monooxygenase |
prostate gland |
- |
686276 |
1.14.14.29 | 25/26-hydroxycholesterol 7alpha-hydroxylase |
prostate gland |
CYP7B1 is overexpressed in high-grade prostatic intraepithelial neoplasia and in prostate cancer |
689846 |
1.14.14.79 | docosahexaenoic acid omega-hydroxylase |
prostate gland |
- |
728344 |
1.14.14.94 | leukotriene-B4 20-monooxygenase |
prostate gland |
mRNA for CYP4F8 detected |
660409 |
1.14.15.18 | calcidiol 1-monooxygenase |
prostate gland |
- |
675686 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
prostate gland |
- |
438404 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
prostate gland |
anterior prostate |
672503 |
1.2.1.3 | aldehyde dehydrogenase (NAD+) |
prostate gland |
- |
655948, 686531 |
1.2.1.31 | L-aminoadipate-semialdehyde dehydrogenase |
prostate gland |
- |
288202 |
1.2.1.31 | L-aminoadipate-semialdehyde dehydrogenase |
prostate gland |
mRNA expression |
675897 |
1.2.1.5 | aldehyde dehydrogenase [NAD(P)+] |
prostate gland |
- |
686531 |
1.21.99.4 | thyroxine 5'-deiodinase |
prostate gland |
- |
701040 |
1.3.1.1 | dihydropyrimidine dehydrogenase (NAD+) |
prostate gland |
- |
685782 |
1.3.1.124 | 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] |
prostate gland |
- |
759825 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
- |
390655, 390656, 390657, 396200, 396204, 396217, 396219, 396220, 656681, 675475, 675683, 686575, 687218, 688684, 688718, 688719, 689849 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
hyperplastic |
396202, 396208, 396211 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
studies in DU 145 cells, a human cell-line of low androgen sensitivity derived from a cerebral metastasis of an ephithelial prostate cancer |
396218, 396223 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
type-2 5alpha-reductase is only found in prostate and other genital tissues, enhancement of type-1 5alpha-reductase is enhanced in prostate cancer |
684816 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
ventral |
396192, 396193, 396209 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
prostate gland |
ventral prostate, activity of both isoform I and II is increased after treatment with oxytocin |
655351 |
1.3.1.70 | DELTA14-sterol reductase |
prostate gland |
TM7SF2 |
672378 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
prostate gland |
- |
-, 657354, 668281, 670738, 712201 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
prostate gland |
prostate cancer cell |
670032 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
prostate gland |
prostate cancer cell lines |
669566 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
prostate gland |
type 2 5alpha-reductase mRNA is predominantly expressed in the prostate gland |
662726 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
prostate gland |
ventral prostate |
669811 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
prostate gland |
very low activity |
391397 |
1.4.3.21 | primary-amine oxidase |
prostate gland |
- |
703130 |
1.4.3.4 | monoamine oxidase |
prostate gland |
is highly expressed in basal cells of the normal prostatic epithelium and in poorly differentiated, aggressive prostate cancer |
702900 |
1.4.3.5 | pyridoxal 5'-phosphate synthase |
prostate gland |
16.5% of the activity in liver |
655483 |
1.5.1.6 | formyltetrahydrofolate dehydrogenase |
prostate gland |
moderate FDH mRNA level |
392350 |
1.5.3.13 | N1-acetylpolyamine oxidase |
prostate gland |
- |
703028 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
prostate gland |
- |
711688 |
1.8.1.9 | thioredoxin-disulfide reductase |
prostate gland |
- |
658795, 701340 |
1.8.1.9 | thioredoxin-disulfide reductase |
prostate gland |
isoform TR1 |
394945 |
1.8.3.2 | thiol oxidase |
prostate gland |
- |
668207 |
1.8.3.2 | thiol oxidase |
prostate gland |
small amounts |
393063 |
1.8.4.2 | protein-disulfide reductase (glutathione) |
prostate gland |
DU145 carcinoma |
394854 |
2.1.1.137 | arsenite methyltransferase |
prostate gland |
moderate expression |
758507 |
2.1.1.137 | arsenite methyltransferase |
prostate gland |
weak expression |
758507 |
2.1.1.20 | glycine N-methyltransferase |
prostate gland |
- |
704524 |
2.1.1.72 | site-specific DNA-methyltransferase (adenine-specific) |
prostate gland |
- |
719373 |
2.3.1.5 | arylamine N-acetyltransferase |
prostate gland |
- |
675601 |
2.3.1.5 | arylamine N-acetyltransferase |
prostate gland |
NAT1 is strongly localized to androgen-positive epithelium in human prostate |
672920 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
prostate gland |
- |
705206 |
2.3.1.56 | aromatic-hydroxylamine O-acetyltransferase |
prostate gland |
- |
487253 |
2.3.1.68 | glutamine N-acyltransferase |
prostate gland |
- |
758269 |
2.3.1.B43 | protein-lysine desuccinylase (NAD+) |
prostate gland |
- |
755970 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
prostate gland |
TG4 expression is restricted to the prostate gland |
759166 |
2.3.2.2 | gamma-glutamyltransferase |
prostate gland |
- |
487898, 487932 |
2.3.2.2 | gamma-glutamyltransferase |
prostate gland |
secretion into seminal plasma |
487940 |
2.3.2.8 | arginyltransferase |
prostate gland |
- |
488023 |
2.3.3.10 | hydroxymethylglutaryl-CoA synthase |
prostate gland |
- |
720426 |
2.4.1.150 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase |
prostate gland |
IGnT is highly expressed in adult prostata |
638567 |
2.4.1.17 | glucuronosyltransferase |
prostate gland |
- |
488786, 488790, 693011 |
2.4.1.214 | glycoprotein 3-alpha-L-fucosyltransferase |
prostate gland |
- |
349718 |
2.4.1.313 | protein O-mannose beta-1,3-N-acetylgalactosaminyltransferase |
prostate gland |
- |
725358 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
prostate gland |
- |
719570 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
prostate gland |
Northern blot analysis of human tissues |
659136 |