EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
peripheral blood mononuclear cell |
- |
741444 |
1.1.1.205 | IMP dehydrogenase |
peripheral blood mononuclear cell |
- |
685852, 703193, 706817 |
1.11.1.9 | glutathione peroxidase |
peripheral blood mononuclear cell |
- |
764714 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
peripheral blood mononuclear cell |
- |
395465, 711580, 712647 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
peripheral blood mononuclear cell |
K562 from human erythroleukemia, human hepatocellular carcinoma cell line HepG2 |
660498 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
peripheral blood mononuclear cell |
constitutive expression of full length nitric oxide synthase isoforms with the highest expression of inducible nitric oxide synthase in comparison to neuronal nitric oxide synthase and endothelial nitric oxide synthase |
724425 |
1.14.14.16 | steroid 21-monooxygenase |
peripheral blood mononuclear cell |
- |
699173 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
peripheral blood mononuclear cell |
- |
733904 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
peripheral blood mononuclear cell |
CD14+ |
733904 |
1.14.16.2 | tyrosine 3-monooxygenase |
peripheral blood mononuclear cell |
- |
746198 |
1.2.4.1 | pyruvate dehydrogenase (acetyl-transferring) |
peripheral blood mononuclear cell |
- |
697756 |
1.3.1.1 | dihydropyrimidine dehydrogenase (NAD+) |
peripheral blood mononuclear cell |
- |
686102, 686495 |
1.8.1.9 | thioredoxin-disulfide reductase |
peripheral blood mononuclear cell |
TrxR activity declines in during the first 21 days in milk. TrxR may be an important antioxidant defense mechanism in peripheral blood mononuclear cells that is compromised during the periparturient period |
687999 |
2.1.1.4 | acetylserotonin O-methyltransferase |
peripheral blood mononuclear cell |
CD19+ cell, CD14-CD4+ cell, CD56-CD8+ cell, CD56+ cell |
662711 |
2.1.1.63 | methylated-DNA-[protein]-cysteine S-methyltransferase |
peripheral blood mononuclear cell |
- |
705497 |
2.1.1.67 | thiopurine S-methyltransferase |
peripheral blood mononuclear cell |
- |
657544 |
2.1.2.3 | phosphoribosylaminoimidazolecarboxamide formyltransferase |
peripheral blood mononuclear cell |
- |
485750 |
2.3.1.256 | N-terminal methionine Nalpha-acetyltransferase NatC |
peripheral blood mononuclear cell |
primary |
756860 |
2.3.1.257 | N-terminal L-serine Nalpha-acetyltransferase NatD |
peripheral blood mononuclear cell |
PBMC |
756553 |
2.3.1.5 | arylamine N-acetyltransferase |
peripheral blood mononuclear cell |
- |
688714, 755743, 755913 |
2.3.1.5 | arylamine N-acetyltransferase |
peripheral blood mononuclear cell |
NAT-1 mRNA expression is found in 5 of 7 examined individuals |
688714 |
2.3.1.97 | glycylpeptide N-tetradecanoyltransferase |
peripheral blood mononuclear cell |
- |
719244 |
2.3.1.97 | glycylpeptide N-tetradecanoyltransferase |
peripheral blood mononuclear cell |
NMT activity is observed to be 3fold higher in peripheral blood mononuclear cells from rats with colonic cancer than in controls, and shows also differential localization |
719244 |
2.4.1.214 | glycoprotein 3-alpha-L-fucosyltransferase |
peripheral blood mononuclear cell |
CD4+ cell |
662566 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
peripheral blood mononuclear cell |
PBMC from blood from healthy individuals |
694813 |
2.4.2.28 | S-methyl-5'-thioadenosine phosphorylase |
peripheral blood mononuclear cell |
CD34+ erythroid burst-forming unit, granulocyte/monocyte colony-forming unit, granulocyte/erythrocyte/macrophage/megakaryocyte colony-forming unit progenitors and primitive high proliferative potential colony-forming cells in the purified CD34+ cells are cultured |
637548 |
2.4.2.3 | uridine phosphorylase |
peripheral blood mononuclear cell |
- |
674024 |
2.4.2.4 | thymidine phosphorylase |
peripheral blood mononuclear cell |
- |
674024, 685817 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
peripheral blood mononuclear cell |
- |
705676 |
2.7.1.1 | hexokinase |
peripheral blood mononuclear cell |
- |
737993 |
2.7.1.138 | ceramide kinase |
peripheral blood mononuclear cell |
very high expression level in resting and low expression level in activated CD4+ cell, resting CD8+ cells, resting, CD14+ cells, higher expression level in resting and low expression level in activated CD19+ cells |
661653 |
2.7.10.2 | non-specific protein-tyrosine kinase |
peripheral blood mononuclear cell |
- |
676043, 761668 |
2.7.11.10 | IkappaB kinase |
peripheral blood mononuclear cell |
- |
675924, 702567, 705315, 705320 |
2.7.11.10 | IkappaB kinase |
peripheral blood mononuclear cell |
CD4+ |
662568 |
2.7.4.14 | UMP/CMP kinase |
peripheral blood mononuclear cell |
- |
645160 |
2.7.4.3 | adenylate kinase |
peripheral blood mononuclear cell |
- |
704723 |
2.7.4.9 | dTMP kinase |
peripheral blood mononuclear cell |
from HIV-infected patients and healthy noninfected individuals. Enzyme activity is 10fold lower in extracts from infected as compared to uninfected persons |
645206 |
2.7.8.17 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase |
peripheral blood mononuclear cell |
- |
645375 |
2.8.2.5 | chondroitin 4-sulfotransferase |
peripheral blood mononuclear cell |
- |
645917 |
3.1.1.56 | methylumbelliferyl-acetate deacetylase |
peripheral blood mononuclear cell |
- |
730315 |
3.1.1.6 | acetylesterase |
peripheral blood mononuclear cell |
high expression on monocytes according to cell-surface domain-specific FACS analyses |
696095 |
3.1.26.11 | tRNase Z |
peripheral blood mononuclear cell |
- |
751915 |
3.1.3.3 | phosphoserine phosphatase |
peripheral blood mononuclear cell |
- |
752146 |
3.1.4.12 | sphingomyelin phosphodiesterase |
peripheral blood mononuclear cell |
- |
730694 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
peripheral blood mononuclear cell |
- |
711379, 711630, 713394 |
3.2.2.27 | uracil-DNA glycosylase |
peripheral blood mononuclear cell |
- |
752157 |
3.3.2.9 | microsomal epoxide hydrolase |
peripheral blood mononuclear cell |
- |
732940 |
3.4.15.1 | peptidyl-dipeptidase A |
peripheral blood mononuclear cell |
PBMC |
753311 |
3.4.17.23 | angiotensin-converting enzyme 2 |
peripheral blood mononuclear cell |
PBMC |
753311 |
3.4.21.20 | cathepsin G |
peripheral blood mononuclear cell |
- |
709983, 718285, 752917 |
3.4.21.26 | prolyl oligopeptidase |
peripheral blood mononuclear cell |
- |
709476 |
3.4.21.37 | leukocyte elastase |
peripheral blood mononuclear cell |
- |
717895 |
3.4.21.78 | granzyme A |
peripheral blood mononuclear cell |
PBMCs, expression in |
683529 |
3.4.21.79 | granzyme B |
peripheral blood mononuclear cell |
- |
679116, 682965, 699669 |
3.4.21.79 | granzyme B |
peripheral blood mononuclear cell |
alloreactive cytotoxic T cell clones |
697194 |
3.4.21.79 | granzyme B |
peripheral blood mononuclear cell |
B19, HBoV1 and Candida albicans antigens are all found to induce peripheral blood mononuclear cell (PBMC) to secrete GrB in 30 parvovirus B19-seropositive and 22 parvovirus B19-seronegative subjects |
753316 |
3.4.21.79 | granzyme B |
peripheral blood mononuclear cell |
cells that do not express either granzyme (gA- or gB-) rarely express perforin and generally express little or no CD57. Granzyme B is never expressed without granzyme A. gA- gB- cells can only express low levels of perforin, as high perforin content requires expression of gA and gB. Less differentiated, naive T cells express no cytotoxic enzymes (gA- gB- Perf-), and nearly all highly differentiated effector T cells (which are largely terminally differentiated CD57 bright cells) express the three cytotoxic enzymes simultaneously. The majority of CMV-specific T cells express gA, gB, and perforin, whereas EBV-specific T cells mostly express gA but not gB and HIV-specific T cells express gA, gB but low levels of perforin |
699410 |
3.4.21.B2 | granzyme M |
peripheral blood mononuclear cell |
- |
709988 |
3.4.22.1 | cathepsin B |
peripheral blood mononuclear cell |
- |
753194 |
3.4.22.36 | caspase-1 |
peripheral blood mononuclear cell |
- |
707154 |
3.4.22.56 | caspase-3 |
peripheral blood mononuclear cell |
- |
708166 |
3.4.22.58 | caspase-5 |
peripheral blood mononuclear cell |
- |
663902 |
3.4.23.34 | cathepsin E |
peripheral blood mononuclear cell |
- |
696014, 709450 |
3.4.24.24 | gelatinase A |
peripheral blood mononuclear cell |
secretion of MMP-2 |
683579 |
3.4.24.35 | gelatinase B |
peripheral blood mononuclear cell |
- |
697747, 708198 |
3.4.24.35 | gelatinase B |
peripheral blood mononuclear cell |
secretion of MMP-9 |
683579 |
3.4.24.71 | endothelin-converting enzyme 1 |
peripheral blood mononuclear cell |
increased ECE-1 content in hypercholesterolemic patients |
699415 |
3.4.24.81 | ADAM10 endopeptidase |
peripheral blood mononuclear cell |
- |
682103 |
3.4.24.86 | ADAM 17 endopeptidase |
peripheral blood mononuclear cell |
- |
711568 |
3.5.1.92 | pantetheine hydrolase |
peripheral blood mononuclear cell |
- |
719161 |
4.2.1.22 | cystathionine beta-synthase |
peripheral blood mononuclear cell |
- |
728945 |
4.4.1.1 | cystathionine gamma-lyase |
peripheral blood mononuclear cell |
peripheral blood mononuclear cells, PBMC, isolated from healthy subjects and type 1 diabetic patients |
730038 |
5.2.1.8 | peptidylprolyl isomerase |
peripheral blood mononuclear cell |
enzyme isoform Pin1 is necessary for activation-dependent mRNA stabilization, accumulation, and protein secretion of cytokine GM-CSF. Pin1 mediates the association of the AU-rich element-binding protein, AUF1, with GM-CSF mRNA |
681198 |
6.1.1.2 | tryptophan-tRNA ligase |
peripheral blood mononuclear cell |
CD4+ cell, CD8+ cell |
661390 |
6.3.2.17 | tetrahydrofolate synthase |
peripheral blood mononuclear cell |
- |
744775 |
6.3.2.2 | glutamate-cysteine ligase |
peripheral blood mononuclear cell |
- |
744853 |
7.1.1.1 | proton-translocating NAD(P)+ transhydrogenase |
peripheral blood mononuclear cell |
- |
764266 |