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Search term: pancreatic islet

Results 1 - 93 of 93
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EC Number Recommended Name Source Tissue Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.14611beta-hydroxysteroid dehydrogenase pancreatic islet 11beta-HSD1 co-localises with glucagon in the periphery of pancreatic islets, but not with insulin or somatostatin 697563
Show all pathways known for 1.1.1.38Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.38malate dehydrogenase (oxaloacetate-decarboxylating) pancreatic islet - 695884
Show all pathways known for 1.1.1.39Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.39malate dehydrogenase (decarboxylating) pancreatic islet - 687568
Show all pathways known for 1.1.1.40Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.40malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) pancreatic islet - 687568, 712942
Show all pathways known for 1.1.1.49Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.49glucose-6-phosphate dehydrogenase (NADP+) pancreatic islet high glucose level of 25 mM leads to a decrease in G6PD activity and protein level in islets 711960
Show all pathways known for 1.1.5.3Display the word mapDisplay the reaction diagram Show all sequences 1.1.5.3glycerol-3-phosphate dehydrogenase pancreatic islet - 690606
Show all pathways known for 1.11.1.9Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.9glutathione peroxidase pancreatic islet - 764706
Show all pathways known for 1.11.1.9Display the word mapDisplay the reaction diagram Show all sequences 1.11.1.9glutathione peroxidase pancreatic islet the intrinsically low level of Gpx activity in the islets sets up the beta cell as an organelle particularly susceptible to oxidative stress secondary to high levels of glucose. Adenoviral overexpression of Gpx increases Gpx activity and protects islets against adverse effects of ribose 660406
Show all pathways known for 1.13.11.31Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.31arachidonate 12-lipoxygenase pancreatic islet - 742000, 765699
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase pancreatic islet - 742000, 765699
Display the word mapDisplay the reaction diagram Show all sequences 1.6.3.1NAD(P)H oxidase (H2O2-forming) pancreatic islet - 711828, 711856
Show all pathways known for 1.6.5.2Display the word mapDisplay the reaction diagram Show all sequences 1.6.5.2NAD(P)H dehydrogenase (quinone) pancreatic islet - 746535
Show all pathways known for 1.8.1.7Display the word mapDisplay the reaction diagram Show all sequences 1.8.1.7glutathione-disulfide reductase pancreatic islet - 394736
Show all pathways known for 1.8.1.7Display the word mapDisplay the reaction diagram Show all sequences 1.8.1.7glutathione-disulfide reductase pancreatic islet high expression level 660485
Show all pathways known for 1.8.1.9Display the word mapDisplay the reaction diagram Show all sequences 1.8.1.9thioredoxin-disulfide reductase pancreatic islet - 394922
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.221tRNA (guanine9-N1)-methyltransferase pancreatic islet - 737064
Show all pathways known for 2.3.1.21Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.21carnitine O-palmitoyltransferase pancreatic islet low content of CPT II, no CPT I 486577
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.61dihydrolipoyllysine-residue succinyltransferase pancreatic islet - 659354
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.255protein O-GlcNAc transferase pancreatic islet - 489616
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.46deoxyhypusine synthase pancreatic islet beta-islet cell -, 721984
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.60protein geranylgeranyltransferase type II pancreatic islet expression of both alpha- and beta-subunit of enzyme as well as Rab escort protein-1 722426
Show all pathways known for 2.7.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1hexokinase pancreatic islet - 641067, 663393, 705294
Show all pathways known for 2.7.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1hexokinase pancreatic islet beta-cells 641068, 641070, 641071
Show all pathways known for 2.7.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1hexokinase pancreatic islet constitutively expressed at a basal rate of 63 pmol/microgram protein/h 671936
Show all pathways known for 2.7.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1hexokinase pancreatic islet glucokinase is inhibited by endogenous long-chain fatty acyl-CoA in islets from omega3-depleted rats. Such an inhibition probably participates to the alteration of D-glucose catabolism prevailing in these islets 685989
Show all pathways known for 2.7.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1hexokinase pancreatic islet highest expression in islet cells 703959
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1056-phosphofructo-2-kinase pancreatic islet - 716226, 94948
Show all pathways known for 2.7.1.11Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.116-phosphofructokinase pancreatic islet - 640501
Show all pathways known for 2.7.1.11Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.116-phosphofructokinase pancreatic islet M-type, i.e. muscle-type, C-type, i.e. fibroplast-type, and perhaps lesser amounts of L-type, i.e. liver-type, PFK isoforms 640496
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.137phosphatidylinositol 3-kinase pancreatic islet - 661681
Show all pathways known for 2.7.1.23Display the reaction diagram Show all sequences 2.7.1.23NAD+ kinase pancreatic islet - 721255
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.3ketohexokinase pancreatic islet - 641283
Show all pathways known for 2.7.1.4Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.4fructokinase pancreatic islet - 674062
Show all pathways known for 2.7.1.40Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.40pyruvate kinase pancreatic islet expression of M2-type pyruvate kinase isoenzyme 721787
Display the word mapDisplay the reaction diagram Show all sequences 2.7.10.1receptor protein-tyrosine kinase pancreatic islet - 490658
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.13protein kinase C pancreatic islet - 491149, 672505
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.30receptor protein serine/threonine kinase pancreatic islet - 664721
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.31[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase pancreatic islet - 701620
Display the word mapDisplay the reaction diagram Show all sequences 2.7.12.2mitogen-activated protein kinase kinase pancreatic islet - 686415
Show all pathways known for 2.7.4.3Display the word mapDisplay the reaction diagram Show all sequences 2.7.4.3adenylate kinase pancreatic islet cytosolic isoforms AK1 and AK5 are expressed in human islets and INS-1 cells. Elevated concentrations of glucose inhibit AK1 expression 690717
Show all pathways known for 2.8.1.2Display the word mapDisplay the reaction diagram Show all sequences 2.8.1.23-mercaptopyruvate sulfurtransferase pancreatic islet - 761948
Show all pathways known for 2.8.3.5Display the word mapDisplay the reaction diagram Show all sequences 2.8.3.53-oxoacid CoA-transferase pancreatic islet - 724109
Show all pathways known for 2.8.3.5Display the word mapDisplay the reaction diagram Show all sequences 2.8.3.53-oxoacid CoA-transferase pancreatic islet of healthy individuals and of type 2 diabetes patients: decreased activity by 92% in the diabetic compared with the non-diabetic islets 703384
Show all pathways known for 3.1.1.23Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.23acylglycerol lipase pancreatic islet - -, 729555, 751941, 94267
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.6acetylesterase pancreatic islet highest expression within pancreatic tissue at the islets of Langerhans, revealed by cytochemistry and confocal microscopy 696095
Show all pathways known for 3.1.3.4Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.4phosphatidate phosphatase pancreatic islet - 134863
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.46fructose-2,6-bisphosphate 2-phosphatase pancreatic islet - -, 678087, 721553, 730691, 94948
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.9glucose-6-phosphatase pancreatic islet - 677468, 697555, 699179, 699609, 701224, 709063, 710573
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.1phosphodiesterase I pancreatic islet - 697620
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.11phosphoinositide phospholipase C pancreatic islet PLC-eta1 668993
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.11phosphoinositide phospholipase C pancreatic islet PLC-eta2 668993
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.50glycosylphosphatidylinositol phospholipase D pancreatic islet islet amyloid 666146
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.533',5'-cyclic-AMP phosphodiesterase pancreatic islet - 690858
Display the word mapDisplay the reaction diagram Show all sequences 3.1.6.13iduronate-2-sulfatase pancreatic islet - 649290, 707060
Show all pathways known for 3.3.2.10Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.10soluble epoxide hydrolase pancreatic islet - 709683
Show all pathways known for 3.3.2.10Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.10soluble epoxide hydrolase pancreatic islet cytosolic localization 662565
Show all pathways known for 3.3.2.10Display the word mapDisplay the reaction diagram Show all sequences 3.3.2.10soluble epoxide hydrolase pancreatic islet exclusively cytosolic 662565
Display the word mapDisplay the reaction diagram Show all sequences 3.4.14.5dipeptidyl-peptidase IV pancreatic islet - 699753
Display the word mapDisplay the reaction diagram Show all sequences 3.4.14.5dipeptidyl-peptidase IV pancreatic islet the enzyme is coexpressed with fibroblast activation protein in adult humans 753766
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.109matriptase pancreatic islet pancreas 698819
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.4trypsin pancreatic islet - 708047
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.61Kexin pancreatic islet - 669436
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.93Proprotein convertase 1 pancreatic islet - 29417, 29871, 668417, 754678
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.93Proprotein convertase 1 pancreatic islet alpha-cells in the islet of Langerhans express both prohormone convertase 2 and 1/3, which results in the processing of the proglucagon precursor into glucagon-like peptide 1, thereby leading to local production of this beta-cell growth factor. alpha-Cells in the adult basically only express PC2, but significant activation of PC1/3 is also observed in mouse models of insulin resistance such as pregnant, obese, diabetic and prediabetic NOD mice 717691
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.94proprotein convertase 2 pancreatic islet - 731759
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.B28fibroblast activation protein alpha subunit pancreatic islet the enzyme is coexpressed with dipeptidyl peptidase-IV in adult humans 753766
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.56caspase-3 pancreatic islet - -, 668726, 700291
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B30calpain 10 pancreatic islet - 666361, 710369
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.24gelatinase A pancreatic islet beta-cell 754619
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.35gelatinase B pancreatic islet - -, 734244
Show all pathways known for 3.5.1.2Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.2glutaminase pancreatic islet - 209033, 667477
Show all pathways known for 3.5.1.2Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.2glutaminase pancreatic islet all the glutaminase activity detected in pancreatic islets is attributed to kidney-type glutaminase and is confined to the mantle of the islet 685413
Show all pathways known for 3.5.1.2Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.2glutaminase pancreatic islet glutaminase activity is confined to the mantle 685413
Show all pathways known for 3.5.1.23Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.23ceramidase pancreatic islet - 752416
Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.18dimethylargininase pancreatic islet - 695485
Show all pathways known for 3.6.1.5Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.5apyrase pancreatic islet highest expression 733060
Display the reaction diagram Show all sequences 3.6.1.8ATP diphosphatase pancreatic islet - 210226
Show all pathways known for 4.1.1.15Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.15glutamate decarboxylase pancreatic islet - -, 697572
Show all pathways known for 4.1.1.28Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.28aromatic-L-amino-acid decarboxylase pancreatic islet - 4207
Show all pathways known for 4.1.2.27Display the word mapDisplay the reaction diagram Show all sequences 4.1.2.27sphinganine-1-phosphate aldolase pancreatic islet - 748220
Show all pathways known for 4.4.1.1Display the word mapDisplay the reaction diagram Show all sequences 4.4.1.1cystathionine gamma-lyase pancreatic islet - 692368
Show all pathways known for 5.3.1.8Display the word mapDisplay the reaction diagram Show all sequences 5.3.1.8mannose-6-phosphate isomerase pancreatic islet - 2812
Show all pathways known for 5.3.99.2Display the word mapDisplay the reaction diagram Show all sequences 5.3.99.2Prostaglandin-D synthase pancreatic islet - 746950
Show all pathways known for 6.2.1.4Display the word mapDisplay the reaction diagram Show all sequences 6.2.1.4succinate-CoA ligase (GDP-forming) pancreatic islet - 672980
Show all pathways known for 6.4.1.1Display the word mapDisplay the reaction diagram Show all sequences 6.4.1.1pyruvate carboxylase pancreatic islet - 673268, 690828, 704841
Show all pathways known for 6.4.1.1Display the word mapDisplay the reaction diagram Show all sequences 6.4.1.1pyruvate carboxylase pancreatic islet increased activity in Zucker fatty rats 652312
Show all pathways known for 6.4.1.2Display the word mapDisplay the reaction diagram Show all sequences 6.4.1.2acetyl-CoA carboxylase pancreatic islet - 671236, 693050
Display the word mapDisplay the reaction diagram Show all sequences 7.1.1.1proton-translocating NAD(P)+ transhydrogenase pancreatic islet - 765394
Display the word mapDisplay the reaction diagram Show all sequences 7.2.2.10P-type Ca2+ transporter pancreatic islet - 719888
Display the word mapDisplay the reaction diagram Show all sequences 7.6.2.1P-type phospholipid transporter pancreatic islet the predominant P4 ATPases in pure pancreatic beta cells and pancreatic islets are ATP8B1, ATP8B2, and ATP9A 734314
Display the word mapDisplay the reaction diagram Show all sequences 7.6.2.1P-type phospholipid transporter pancreatic islet the predominant P4 ATPases in pure pancreatic beta cells and pancreatic islets are ATP8B1, ATP8B2, and ATP9A. ATP8B1 and CDC50A are highly concentrated in insulin secretory granules 734314
Display the word mapDisplay the reaction diagram Show all sequences 7.6.2.1P-type phospholipid transporter pancreatic islet the predominant P4 ATPases in pure pancreatic beta cells and pancreatic islets are ATP8B1, ATP8B2, and ATP9A. ATP9A is concentrated in plasma membrane 734314
Display the word mapDisplay the reaction diagram Show all sequences 7.6.2.1P-type phospholipid transporter pancreatic islet the predominant P4 ATPases in pure pancreatic beta cells and pancreatic islets are ATP8B1, ATP8B2, and ATP9A. Isoform ATP8B1 is highly concentrated in insulin secretory granules 734314
Results 1 - 93 of 93
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