EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.153 | sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) |
neuroblastoma cell |
SPR mRNA expression is highest in all neuroblastoma clinical groups with poor outcome |
740231 |
1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
neuroblastoma cell |
- |
745939 |
1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
neuroblastoma cell |
lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma |
753142 |
1.14.14.25 | cholesterol 24-hydroxylase |
neuroblastoma cell |
- |
684856, 711641 |
1.14.16.2 | tyrosine 3-monooxygenase |
neuroblastoma cell |
37 different tumor samples, analysis of enzyme expression |
685447 |
1.14.17.1 | dopamine beta-monooxygenase |
neuroblastoma cell |
- |
744851 |
1.14.17.1 | dopamine beta-monooxygenase |
neuroblastoma cell |
SH-SY5Y-AH1861 |
659260 |
1.14.99.66 | [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase |
neuroblastoma cell |
lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma |
753142 |
1.17.3.2 | xanthine oxidase |
neuroblastoma cell |
- |
685028 |
1.2.1.12 | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) |
neuroblastoma cell |
- |
687602, 763665 |
1.4.3.4 | monoamine oxidase |
neuroblastoma cell |
- |
703615 |
1.4.3.4 | monoamine oxidase |
neuroblastoma cell |
SK-N-BE(2)-C |
674612 |
1.5.3.16 | spermine oxidase |
neuroblastoma cell |
- |
691035, 725069 |
1.6.2.2 | cytochrome-b5 reductase |
neuroblastoma cell |
- |
741562 |
1.8.3.2 | thiol oxidase |
neuroblastoma cell |
immunohistochemical expression of the protein quiescin sulfhydryl oxidase 1 (QSOX1) in samples obtained from untreated neuroblastomas with the patients' clinical and pathological prognostic factors and clinical course. The immunoexpression of QSOX1 correlates with the type of tumor stroma and is higher in Schwannian stroma-rich tumors. Statistically significant correlation between QSOX1 expression and well-differentiated neuroblastomas |
742434 |
2.1.1.137 | arsenite methyltransferase |
neuroblastoma cell |
- |
695519 |
2.1.1.220 | tRNA (adenine58-N1)-methyltransferase |
neuroblastoma cell |
from adrenal gland |
721024 |
2.1.1.233 | [phosphatase 2A protein]-leucine-carboxy methyltransferase |
neuroblastoma cell |
- |
715981, 736425 |
2.1.1.360 | [histone H3]-lysine79 N-trimethyltransferase |
neuroblastoma cell |
- |
753144 |
2.1.1.45 | thymidylate synthase |
neuroblastoma cell |
- |
485375 |
2.1.1.77 | protein-L-isoaspartate(D-aspartate) O-methyltransferase |
neuroblastoma cell |
- |
757812 |
2.3.1.24 | sphingosine N-acyltransferase |
neuroblastoma cell |
- |
753141 |
2.3.1.26 | sterol O-acyltransferase |
neuroblastoma cell |
- |
736702 |
2.3.1.43 | phosphatidylcholine-sterol O-acyltransferase |
neuroblastoma cell |
- |
736674 |
2.3.1.48 | histone acetyltransferase |
neuroblastoma cell |
from neuronal tissue |
735770 |
2.3.1.6 | choline O-acetyltransferase |
neuroblastoma cell |
- |
702964 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
neuroblastoma cell |
- |
735910, 759712 |
2.3.2.5 | glutaminyl-peptide cyclotransferase |
neuroblastoma cell |
- |
736887 |
2.4.1.152 | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase |
neuroblastoma cell |
CHP 134 |
349722 |
2.4.1.155 | alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase |
neuroblastoma cell |
higher expression of GnT-V is correlated with a favorable prognosis for neuroblastoma patients. GnT-V may cause these tumors to regress by increasing their susceptibility to apoptosis |
673674 |
2.4.1.41 | polypeptide N-acetylgalactosaminyltransferase |
neuroblastoma cell |
ppGalNAc-T13 is abundantly expressed in neuroblastoma cells |
489184 |
2.4.1.90 | N-acetyllactosamine synthase |
neuroblastoma cell |
- |
735973 |
2.4.1.92 | (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase |
neuroblastoma cell |
- |
705475 |
2.4.2.12 | nicotinamide phosphoribosyltransferase |
neuroblastoma cell |
- |
735872 |
2.4.3.8 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase |
neuroblastoma cell |
- |
759358, 764812 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
neuroblastoma cell |
murine neuroblastoma x rat dorsal root ganglion F-11A cells |
489583 |
2.5.1.46 | deoxyhypusine synthase |
neuroblastoma cell |
- |
758759 |
2.7.1.107 | diacylglycerol kinase (ATP) |
neuroblastoma cell |
- |
760468 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
neuroblastoma cell |
- |
761670 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
neuroblastoma cell |
PI3K class IIbeta (PI3KC2beta) and its regulator intersectin 1 (ITSN1) are highly expressed in primary neuroblastoma tumors and cell lines |
737972 |
2.7.1.32 | choline kinase |
neuroblastoma cell |
- |
673201 |
2.7.1.48 | uridine/cytidine kinase |
neuroblastoma cell |
- |
737778 |
2.7.1.48 | uridine/cytidine kinase |
neuroblastoma cell |
generation of a specific antibody against UCK1 and analysis of expression of both UCK isoforms 1 and 2 in a panel of neuroblastoma cell lines, overview. No differences are observed for UCK1 and UCK2 expression between MYCN-single copy cell lines and MYCN-amplified neuroblastoma cell lines |
759866 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
neuroblastoma cell |
- |
673232 |
2.7.1.68 | 1-phosphatidylinositol-4-phosphate 5-kinase |
neuroblastoma cell |
- |
660641 |
2.7.1.91 | sphingosine kinase |
neuroblastoma cell |
- |
671356, 761593 |
2.7.10.1 | receptor protein-tyrosine kinase |
neuroblastoma cell |
C1300 cells |
490180 |
2.7.10.1 | receptor protein-tyrosine kinase |
neuroblastoma cell |
high expression of TrkA in neuroblastomas with favorable biological features and is highly correlated with patient survival, whereas TrkB is mainly expressed on unfavorable, aggressive neuroblastomas. TrkC is highly expressed in favorable neuroblastomas |
692018 |
2.7.10.2 | non-specific protein-tyrosine kinase |
neuroblastoma cell |
- |
705943 |
2.7.11.12 | cGMP-dependent protein kinase |
neuroblastoma cell |
- |
662949 |
2.7.11.13 | protein kinase C |
neuroblastoma cell |
- |
672842, 761892 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
neuroblastoma cell |
- |
491279 |
2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
neuroblastoma cell |
CaMKII is induced by neural differentiation of the embryonic carcinoma cells |
664278 |
2.7.11.21 | polo kinase |
neuroblastoma cell |
- |
662229, 741007 |
2.7.11.22 | cyclin-dependent kinase |
neuroblastoma cell |
- |
662152, 664179, 722194 |
2.7.11.24 | mitogen-activated protein kinase |
neuroblastoma cell |
- |
692440, 740750 |
2.7.11.26 | tau-protein kinase |
neuroblastoma cell |
- |
662152, 739962, 761718 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
neuroblastoma cell |
- |
693047, 705939 |
2.7.4.6 | nucleoside-diphosphate kinase |
neuroblastoma cell |
- |
690805 |
2.7.8.11 | CDP-diacylglycerol-inositol 3-phosphatidyltransferase |
neuroblastoma cell |
- |
645316 |
2.8.1.2 | 3-mercaptopyruvate sulfurtransferase |
neuroblastoma cell |
- |
713731 |
2.8.2.1 | aryl sulfotransferase |
neuroblastoma cell |
- |
675515 |
2.8.3.5 | 3-oxoacid CoA-transferase |
neuroblastoma cell |
decreased expression of SCOT protein, neuroblastoma cells are unable to use ketone bodies as an energy source |
705310 |
3.1.1.1 | carboxylesterase |
neuroblastoma cell |
- |
729652 |
3.1.1.116 | sn-1-specific diacylglycerol lipase |
neuroblastoma cell |
- |
761970 |
3.1.1.4 | phospholipase A2 |
neuroblastoma cell |
SH-5YSY cell |
708995 |
3.1.11.7 | adenosine-5'-diphospho-5'-[DNA] diphosphatase |
neuroblastoma cell |
- |
750720 |
3.1.2.22 | palmitoyl[protein] hydrolase |
neuroblastoma cell |
- |
751407 |
3.1.3.16 | protein-serine/threonine phosphatase |
neuroblastoma cell |
MKP-8 is highly expressed in neuroblastoma |
692321 |
3.1.3.67 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase |
neuroblastoma cell |
the disruption of the PTEN/MMAC1 gene is not a frequent event in neuroblastoma. This disruption may be responsible for malignant progression in only a limited proportion of cases of neuroblastoma |
650758 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
neuroblastoma cell |
PDE5 is induced in neuroblastoma-glioma NG108-15 cells after dibutyryl treatment |
650342 |
3.1.4.39 | alkylglycerophosphoethanolamine phosphodiesterase |
neuroblastoma cell |
- |
696397 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
neuroblastoma cell |
- |
730171 |
3.1.6.13 | iduronate-2-sulfatase |
neuroblastoma cell |
- |
650371 |
3.2.1.45 | glucosylceramidase |
neuroblastoma cell |
- |
751699 |
3.3.2.6 | leukotriene-A4 hydrolase |
neuroblastoma cell |
- |
752495 |
3.4.17.17 | tubulinyl-Tyr carboxypeptidase |
neuroblastoma cell |
N2a cells, high level of MAP1B expression |
686295 |
3.4.19.1 | acylaminoacyl-peptidase |
neuroblastoma cell |
isolated from serum-free conditioned medium |
688494 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
neuroblastoma cell |
- |
709780 |
3.4.21.108 | HtrA2 peptidase |
neuroblastoma cell |
- |
668876 |
3.4.21.26 | prolyl oligopeptidase |
neuroblastoma cell |
- |
669933, 683344 |
3.4.21.35 | tissue kallikrein |
neuroblastoma cell |
- |
681754 |
3.4.22.1 | cathepsin B |
neuroblastoma cell |
- |
678362, 707971 |
3.4.22.15 | cathepsin L |
neuroblastoma cell |
- |
712921 |
3.4.22.55 | caspase-2 |
neuroblastoma cell |
- |
701085, 711697 |
3.4.22.56 | caspase-3 |
neuroblastoma cell |
- |
701099 |
3.4.22.59 | caspase-6 |
neuroblastoma cell |
- |
718301 |
3.4.22.60 | caspase-7 |
neuroblastoma cell |
- |
701085 |
3.4.22.61 | caspase-8 |
neuroblastoma cell |
- |
700575 |
3.4.22.62 | caspase-9 |
neuroblastoma cell |
- |
717529 |
3.4.22.63 | caspase-10 |
neuroblastoma cell |
low expression level |
717459 |
3.4.22.B25 | calpain 5 |
neuroblastoma cell |
- |
732139 |
3.4.22.B70 | SENP1 peptidase |
neuroblastoma cell |
metastatic neuroblastoma tissue |
731513 |
3.4.22.B71 | SENP2 peptidase |
neuroblastoma cell |
- |
732487 |
3.4.23.46 | memapsin 2 |
neuroblastoma cell |
- |
713121 |
3.4.24.11 | neprilysin |
neuroblastoma cell |
- |
755120, 755423 |
3.4.24.35 | gelatinase B |
neuroblastoma cell |
- |
710077 |
3.4.24.71 | endothelin-converting enzyme 1 |
neuroblastoma cell |
primary |
683434 |
3.4.24.81 | ADAM10 endopeptidase |
neuroblastoma cell |
strain SH-SY5Y |
669926 |
3.5.1.23 | ceramidase |
neuroblastoma cell |
- |
752416 |