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Search term: mesangial cell
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29
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EC Number
Recommended Name
Source Tissue
Commentary
Reference
1.1.1.21
aldose reductase
mesangial cell
-
668699
,
700118
2.3.1.67
1-alkylglycerophosphocholine O-acetyltransferase
mesangial cell
human mesangial cell line
701601
2.3.1.67
1-alkylglycerophosphocholine O-acetyltransferase
mesangial cell
the enzyme is activated under inflammatory conditions
675778
2.3.3.8
ATP citrate synthase
mesangial cell
-
755769
,
756693
2.4.1.212
hyaluronan synthase
mesangial cell
-
695183
2.4.2.1
purine-nucleoside phosphorylase
mesangial cell
-
-
,
760109
2.7.1.107
diacylglycerol kinase (ATP)
mesangial cell
diaclyglycerol kinase activity is reduced by oxidative stress in glomerular mesangial cells cultured under high glucose conditions. Antioxidants, including D-alpha-tocopherol and probucol may improve hyperglycemia-induced diacylglycerol-protein kinase C activation by enhancing diacylglycerol kinase activity
723202
2.7.1.138
ceramide kinase
mesangial cell
glomerular
738014
2.7.1.91
sphingosine kinase
mesangial cell
-
672834
2.7.1.91
sphingosine kinase
mesangial cell
renal mesangial cell
702503
2.7.10.2
non-specific protein-tyrosine kinase
mesangial cell
-
490641
2.7.8.2
diacylglycerol cholinephosphotransferase
mesangial cell
HMC, immortilized by transfection with T-antigen of SV40 and Hras oncogene
693986
3.1.1.4
phospholipase A2
mesangial cell
-
750503
3.1.3.16
protein-serine/threonine phosphatase
mesangial cell
-
693027
3.1.3.2
acid phosphatase
mesangial cell
-
666100
3.1.4.1
phosphodiesterase I
mesangial cell
-
208380
3.1.4.12
sphingomyelin phosphodiesterase
mesangial cell
-
678375
3.4.11.7
glutamyl aminopeptidase
mesangial cell
-
683521
3.4.15.1
peptidyl-dipeptidase A
mesangial cell
primary
-
,
752438
3.4.19.12
ubiquitinyl hydrolase 1
mesangial cell
MES13 cell line
731221
3.4.21.39
chymase
mesangial cell
-
697785
3.4.21.68
t-Plasminogen activator
mesangial cell
incubated with culture medium containing polyriboinosinic:polyribocytidylic acid RNA in different concentrations
710061
3.4.21.7
plasmin
mesangial cell
-
688737
3.4.23.15
renin
mesangial cell
-
667164
3.4.23.15
renin
mesangial cell
active renin is significantly higher in the cell lysate than in culture medium. Inactive prorenin is similar for the intracellular and extracellular compartments. Free active renin is the predominant form found in both cell compartments. Mesangial cells in culture are able to synthesize and translate renin mRNA probably as inactive prorenin which is mostly processed to active renin inside the cells. The cells secrete both forms of the enzyme but at lower level compared with intracellular content
650745
3.4.24.81
ADAM10 endopeptidase
mesangial cell
-
677996
3.6.5.2
small monomeric GTPase
mesangial cell
small GTPase Rac-1 is a regulator of mesangial cell morphology and thrombospondin-1 expression
684371
4.6.1.2
guanylate cyclase
mesangial cell
-
691401
5.3.99.4
prostaglandin-I synthase
mesangial cell
-
748544
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