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Search term: macrophage

Results 1 - 100 of 465 > >>
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EC Number Recommended Name Source Tissue Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.251,4-lactonase macrophage - 692438
Show all pathways known for 2.3.1.23Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.231-acylglycerophosphocholine O-acyltransferase macrophage - 704461, 736546, 756102
Show all pathways known for 2.3.1.23Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.231-acylglycerophosphocholine O-acyltransferase macrophage primary peripheral blood macrophages 735571
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.471-alkyl-2-acetylglycerophosphocholine esterase macrophage - 650339, 652685, 678390, 690321, 690322, 690673, 691653, 691929, 693526
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.471-alkyl-2-acetylglycerophosphocholine esterase macrophage decidual and monocyte-derived 650326
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.471-alkyl-2-acetylglycerophosphocholine esterase macrophage increased enzyme expression in artheriosclerosis 650932
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.471-alkyl-2-acetylglycerophosphocholine esterase macrophage no significant modifications of pPAF-AH mRNA in macrophages or in ApoB100 values is observed in hepatitis C virus patients compared with controls 681670
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.471-alkyl-2-acetylglycerophosphocholine esterase macrophage peritoneal 650326
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.471-alkyl-2-acetylglycerophosphocholine esterase macrophage resident ones of the liver, and peritoneal 652009
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.471-alkyl-2-acetylglycerophosphocholine esterase macrophage secretion 649802
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.471-alkyl-2-acetylglycerophosphocholine esterase macrophage secretion of plasma isozyme after cleavage of the signal peptide at Ala17/Val18, high enzyme activity during differentiation of monocytes to macrophages 653695
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.671-alkylglycerophosphocholine O-acetyltransferase macrophage - 736604
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.671-alkylglycerophosphocholine O-acetyltransferase macrophage bone marrow-derived 735644
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.14611beta-hydroxysteroid dehydrogenase macrophage activity occurs after differentiation of neutrophils to macrophages 669730
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.14611beta-hydroxysteroid dehydrogenase macrophage derived from bone-marrow, peritoneal macrophages, expression of isozyme 11beta-HSD1, not isozyme 11beta-HSD2 669730
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.14611beta-hydroxysteroid dehydrogenase macrophage isoform 11betaHSD2 741066
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.2925/26-hydroxycholesterol 7alpha-hydroxylase macrophage bone marrow-derived 699414
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.533',5'-cyclic-AMP phosphodiesterase macrophage PDE4B. Ablation of PDE4B partially protects mice from LPS-induced shock 669723
Show all pathways known for 1.3.1.21Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.217-dehydrocholesterol reductase macrophage - 763129
Show all pathways known for 3.1.3.2Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.2acid phosphatase macrophage - 134784, 652665, 666100, 679089
Show all pathways known for 3.1.3.2Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.2acid phosphatase macrophage isozyme 5a, secretion 665956
Show all pathways known for 3.1.1.23Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.23acylglycerol lipase macrophage - 751669
Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.77acyloxyacyl hydrolase macrophage - 246553
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.86ADAM 17 endopeptidase macrophage - 638980, 639001, 639002, 639013, 681031
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B28ADAM15 macrophage - 733818
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B9ADAM9 endopeptidase macrophage in advanced human atherosclerotic plaques of aorta and carotid and femoral arteries, high expression level 710868
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.82ADAMTS-4 endopeptidase macrophage - 677894, 679302
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B11ADAMTS1 endopeptidase macrophage - 669350, 755146
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.B11ADAMTS1 endopeptidase macrophage macrophages at sites of muscle injury induce activation of satellite cells via expression of Adamts1 754846
Display the reaction diagram Show all sequences 2.7.7.96ADP-D-ribose pyrophosphorylase macrophage - 684834
Show all pathways known for 1.1.1.21Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.21aldose reductase macrophage - -, 669503, 738833, 739113
Show all pathways known for 1.1.1.21Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.21aldose reductase macrophage in inflamed temporal arteries 668868
Display the word mapDisplay the reaction diagram Show all sequences 1.14.16.5alkylglycerol monooxygenase macrophage - 746303
Display the word mapDisplay the reaction diagram Show all sequences 3.4.17.23angiotensin-converting enzyme 2 macrophage - 679704, 681180, 708649
Show all pathways known for 3.6.1.5Display the word mapDisplay the reaction diagram Show all sequences 3.6.1.5apyrase macrophage - -, 756375
Show all pathways known for 1.13.11.31Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.31arachidonate 12-lipoxygenase macrophage - -, 704947, 726846, 741573
Show all pathways known for 1.13.11.31Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.31arachidonate 12-lipoxygenase macrophage 12/15-LOX is a macrophage-selective regulator of interleukin-12 production -, 704003
Show all pathways known for 1.13.11.31Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.31arachidonate 12-lipoxygenase macrophage 12/15-LOX is expressed by 95% of resident peritoneal CD11bhigh cells, with the remaining 5% being 12/15-LOX-. 12/15-LOX+ cells are phenotypically defined by high F4/80, SR-A, and Siglec1 expression, and enhanced IL-10 and G-CSF generation. In contrast, 12/15-LOX- cells are a dendritic cell population. Resident peritoneal macrophage numbers are significantly increased in 12/15-LOX-/- mice, suggesting alterations in migratory trafficking or cell differentiation in vivo -, 704943
Show all pathways known for 1.13.11.31Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.31arachidonate 12-lipoxygenase macrophage macrophages that overexpress 12/15LO have reduced ATP-binding cassette G1 expression, increased transporter phosphorylation, and reduced cholesterol efflux 704567
Show all pathways known for 1.13.11.31Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.31arachidonate 12-lipoxygenase macrophage peritoneal -, 684803
Show all pathways known for 1.13.11.31Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.31arachidonate 12-lipoxygenase macrophage resident peritoneal 742000
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage - 703628, 742239
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage 12/15-LOX is a macrophage-selective regulator of interleukin-12 production -, 704003
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage 12/15-LOX is expressed by 95% of resident peritoneal CD11bhigh cells, with the remaining 5% being 12/15-LOX-. 12/15-LOX+ cells are phenotypically defined by high F4/80, SR-A, and Siglec1 expression, and enhanced IL-10 and G-CSF generation. In contrast, 12/15-LOX- cells are a dendritic cell population. Resident peritoneal macrophage numbers are significantly increased in 12/15-LOX-/- mice, suggesting alterations in migratory trafficking or cell differentiation in vivo -, 704943
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage alveolar 742613
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage high level expression in peritoneal macrophages, while murine peripheral monocytes, alveolar macrophages and bone marrow-derived macrophages express alox15 only at low levels 742613
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage isozyme 15-LO-1, differentiated monocytes obtained from human venous blood, CD14+ 687235
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage peritoneal -, 684350
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage resident peritoneal 742000
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage rheumatoid arthritis tissue 701978
Show all pathways known for 1.13.11.34Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.34arachidonate 5-lipoxygenase macrophage - 660111, 704997, 711100, 713540, 743614
Show all pathways known for 1.13.11.34Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.34arachidonate 5-lipoxygenase macrophage alveolar macrophage 742001
Show all pathways known for 3.5.3.1Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.1arginase macrophage - 684384, 688998, 689301
Show all pathways known for 3.5.3.1Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.1arginase macrophage alveolar macrophage 667160, 686562
Show all pathways known for 3.5.3.1Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.1arginase macrophage cultured head-kidney derived macrophages, significant enzyme activity, inhibitable by Nomega-hydroxy-L-arginine and induced by dibutyryl cyclic adenosine 670294
Show all pathways known for 3.5.3.1Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.1arginase macrophage cultured head-kidney derived macrophages, significant enzyme activity, inhibitable by Nomega-hydroxy-L-arginine, not inducible by dibutyryl cyclic adenosine 670294
Show all pathways known for 3.5.3.1Display the word mapDisplay the reaction diagram Show all sequences 3.5.3.1arginase macrophage type I 701646
Show all pathways known for 4.1.1.28Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.28aromatic-L-amino-acid decarboxylase macrophage - 705269
Show all pathways known for 3.1.1.2Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.2arylesterase macrophage - 692438
Display the word mapDisplay the reaction diagram Show all sequences 3.1.6.1arylsulfatase (type I) macrophage - 709806
Display the word mapDisplay the reaction diagram Show all sequences 7.2.1.3ascorbate ferrireductase (transmembrane) macrophage - 744757
Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.15aspartoacylase macrophage resident peritoneal 734393
Show all pathways known for 2.3.3.8Display the word mapDisplay the reaction diagram Show all sequences 2.3.3.8ATP citrate synthase macrophage - 735597
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.15beta-adrenergic-receptor kinase macrophage - -, 673187
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.15beta-adrenergic-receptor kinase macrophage peritoneal macrophages, activation of Toll-like receptors significantly increases GRK2 expression in primary macrophages, mechanism, overview -, 689035
Display the reaction diagram Show all sequences 2.4.3.1beta-galactoside alpha-(2,6)-sialyltransferase macrophage - 722730
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.38beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase macrophage high expression level 687078
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.52beta-N-acetylhexosaminidase macrophage the importance of beta-hexosaminidase for restricting mycobacterial growth during mammalian infections is confirmed in macrophages from beta-hexosaminidase knockout mice. beta-Hexosaminidase is characterized as a peptidoglycan hydrolase that exerts its mycobactericidal effect at the macrophage plasma membrane during mycobacteria-induced secretion of lysosomes 682592
Show all pathways known for 1.3.1.24Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.24biliverdin reductase macrophage - 673797, 698922, 740486, 740549
Show all pathways known for 1.3.1.24Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.24biliverdin reductase macrophage increased expression in macrophages of primary spontaneous pneumothorax of smokers compared to non-smokers 713359
Show all pathways known for 1.3.1.24Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.24biliverdin reductase macrophage lung 713359
Show all pathways known for 2.6.1.42Display the word mapDisplay the reaction diagram Show all sequences 2.6.1.42branched-chain-amino-acid transaminase macrophage - 758657
Show all pathways known for 1.14.15.18Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.18calcidiol 1-monooxygenase macrophage - 675057, 675686
Show all pathways known for 1.14.15.18Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.18calcidiol 1-monooxygenase macrophage expression of 1alpha-hydroxylase is intimately associated with toll-like receptor, TLR, recognition of pathogens in macrophages 712885
Show all pathways known for 1.14.15.18Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.18calcidiol 1-monooxygenase macrophage monocyte-derived 688675
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B26calpain 6 macrophage - 754258
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.52calpain-1 macrophage - 708717
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.53calpain-2 macrophage - 717847
Show all pathways known for 3.1.1.1Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.1carboxylesterase macrophage - 691075
Show all pathways known for 3.1.1.1Display the word mapDisplay the reaction diagram Show all sequences 3.1.1.1carboxylesterase macrophage CES1, no expression of CES2 707570
Display the word mapDisplay the reaction diagram Show all sequences 3.4.17.1carboxypeptidase A macrophage in primary macrophages, CPVL is glycosylated with high mannose residues 687160
Display the word mapDisplay the reaction diagram Show all sequences 3.4.16.5carboxypeptidase C macrophage of lung 665905
Display the word mapDisplay the reaction diagram Show all sequences 3.4.17.12carboxypeptidase M macrophage - 670291
Display the word mapDisplay the reaction diagram Show all sequences 3.4.17.12carboxypeptidase M macrophage CPM expression is the highest in macrophages 697395
Display the word mapDisplay the reaction diagram Show all sequences 3.4.17.20Carboxypeptidase U macrophage - 670940
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage - -, 679079, 681017, 681030, 697733, 698235, 700198, 700362, 700983, 708709, 708712, 717941, 718077
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage bone marrow-derived -, 698251, 699349
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage bone marrow-derived macrophage, BMDM cell -, 697199, 698245
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage bone marrow-derived macrophages, wild-type and superoxide dismutase-deficient 700365
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage bone-marrow derived 670356
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage bone-marrow-derived 700393
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage caspase-1-mediated macrophage necrosis is the source of the cytokine storm and rapid disease progression in anthrax lethal toxin-treated BALB/c mice 679097
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage IFN regulatory factor IRF-2(-/-) macrophages exhibit increased basal and gliotoxin-induced caspase-1 mRNA expression and enhanced caspase-1 activity 681202
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage inactive 45000 Da proform of caspase-1 is basally expressed in macrophages, virus infection induces the cleavage of procaspase into the mature 20000 Da form 647636
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage bone marrow derived. Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms. Activation of caspase-1 by Bacillus anthracis lethal toxin requires binding, uptake, and endosome acidification to mediate translocation of lethal factor into the host cell cytosol. Catalytically active lethal factor cleaves cytosolic substrates and activates caspase-1 by a mechanism involving proteasome activity and potassium efflux. Lethal toxin activation of caspase-1 requires the inflammasome adapter Nalp1. Salmonella infection activates caspase-1 through an independent pathway requiring the inflammasome adapter Ipaf. These distinct mechanisms of caspase-1 activation converge on a common pathway of caspase-1-dependent cell death featuring DNA cleavage, cytokine activation, and, ultimately, cell lysis resulting from the formation of membrane pores between 1.1 and 2.4 nm in diameter and pathological ion fluxes that can be blocked by glycine 682588
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage macrophage-like J774.1 cells 701307
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage peritoneal 698242
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage the Gram-negative bacterium Shigella flexneri triggers pro-inflammatory apoptotic cell death in macrophages, which is crucial for the onset of an acute inflammatory diarrhoea termed bacillary dysentery. The Mxi-Spa type III secretion system promotes bacterial uptake and escape into the cytoplasm, where, dependent on the translocator/effector protein IpaB, caspase-1 and its substrate IL-1b are activated 681799
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.36caspase-1 macrophage wild-type and TLR4 knockout macrophage 699326
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.64caspase-11 macrophage - 698218, 699327, 731744, 731905
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