Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Source Tissue

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search
Show additional data
do not include text mining results
include AMENDA results (Automatic Mining of Enzyme Data)

Search term: macrophage

Results 1 - 100 of 465 > >>
download as CSV
download all results as CSV
EC Number Recommended Name Source Tissue Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.14611beta-hydroxysteroid dehydrogenase macrophage activity occurs after differentiation of neutrophils to macrophages 669730
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.14611beta-hydroxysteroid dehydrogenase macrophage derived from bone-marrow, peritoneal macrophages, expression of isozyme 11beta-HSD1, not isozyme 11beta-HSD2 669730
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.14611beta-hydroxysteroid dehydrogenase macrophage isoform 11betaHSD2 741066
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.153sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) macrophage - 286017
Show all pathways known for 1.1.1.188Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.188prostaglandin-F synthase macrophage peritoneal 654851
Show all pathways known for 1.1.1.21Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.21aldose reductase macrophage - -, 669503, 738833, 739113
Show all pathways known for 1.1.1.21Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.21aldose reductase macrophage in inflamed temporal arteries 668868
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.271GDP-L-fucose synthase macrophage - 667231
Show all pathways known for 1.1.1.49Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.49glucose-6-phosphate dehydrogenase (NADP+) macrophage - 655495
Display the word mapDisplay the reaction diagram Show all sequences 1.11.2.2myeloperoxidase macrophage - 697307, 700458
Show all pathways known for 1.13.11.11Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.11tryptophan 2,3-dioxygenase macrophage - 743358
Show all pathways known for 1.13.11.31Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.31arachidonate 12-lipoxygenase macrophage - -, 704947, 726846, 741573
Show all pathways known for 1.13.11.31Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.31arachidonate 12-lipoxygenase macrophage 12/15-LOX is a macrophage-selective regulator of interleukin-12 production -, 704003
Show all pathways known for 1.13.11.31Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.31arachidonate 12-lipoxygenase macrophage 12/15-LOX is expressed by 95% of resident peritoneal CD11bhigh cells, with the remaining 5% being 12/15-LOX-. 12/15-LOX+ cells are phenotypically defined by high F4/80, SR-A, and Siglec1 expression, and enhanced IL-10 and G-CSF generation. In contrast, 12/15-LOX- cells are a dendritic cell population. Resident peritoneal macrophage numbers are significantly increased in 12/15-LOX-/- mice, suggesting alterations in migratory trafficking or cell differentiation in vivo -, 704943
Show all pathways known for 1.13.11.31Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.31arachidonate 12-lipoxygenase macrophage macrophages that overexpress 12/15LO have reduced ATP-binding cassette G1 expression, increased transporter phosphorylation, and reduced cholesterol efflux 704567
Show all pathways known for 1.13.11.31Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.31arachidonate 12-lipoxygenase macrophage peritoneal -, 684803
Show all pathways known for 1.13.11.31Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.31arachidonate 12-lipoxygenase macrophage resident peritoneal 742000
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage - 703628, 742239
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage 12/15-LOX is a macrophage-selective regulator of interleukin-12 production -, 704003
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage 12/15-LOX is expressed by 95% of resident peritoneal CD11bhigh cells, with the remaining 5% being 12/15-LOX-. 12/15-LOX+ cells are phenotypically defined by high F4/80, SR-A, and Siglec1 expression, and enhanced IL-10 and G-CSF generation. In contrast, 12/15-LOX- cells are a dendritic cell population. Resident peritoneal macrophage numbers are significantly increased in 12/15-LOX-/- mice, suggesting alterations in migratory trafficking or cell differentiation in vivo -, 704943
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage alveolar 742613
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage high level expression in peritoneal macrophages, while murine peripheral monocytes, alveolar macrophages and bone marrow-derived macrophages express alox15 only at low levels 742613
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage isozyme 15-LO-1, differentiated monocytes obtained from human venous blood, CD14+ 687235
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage peritoneal -, 684350
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage resident peritoneal 742000
Show all pathways known for 1.13.11.33Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.33arachidonate 15-lipoxygenase macrophage rheumatoid arthritis tissue 701978
Show all pathways known for 1.13.11.34Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.34arachidonate 5-lipoxygenase macrophage - 660111, 704997, 711100, 713540, 743614
Show all pathways known for 1.13.11.34Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.34arachidonate 5-lipoxygenase macrophage alveolar macrophage 742001
Show all pathways known for 1.13.11.52Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.52indoleamine 2,3-dioxygenase macrophage - 666461, 711952, 743358
Show all pathways known for 1.13.11.52Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.52indoleamine 2,3-dioxygenase macrophage enzyme is induced in monocyte-derived macrophages treated with human recombinant interferon-beta or interferon gamma 395468
Show all pathways known for 1.13.11.52Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.52indoleamine 2,3-dioxygenase macrophage in the villous stroma and in the fetal membrane 659803
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.29hypoxia-inducible factor-proline dioxygenase macrophage - 745510
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.68[histone H3]-trimethyl-L-lysine27 demethylase macrophage expressed in macrophages in response to bacterial products and inflammatory cytokines 753165
Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.39nitric-oxide synthase (NADPH) macrophage - -, 440193, 440195, 440198, 440204, 440206, 440207, 440208, 440209, 440219, 440226, 440234, 440236, 674558
Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.39nitric-oxide synthase (NADPH) macrophage alveolar 690183
Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.39nitric-oxide synthase (NADPH) macrophage bone marrow-derived 687727
Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.39nitric-oxide synthase (NADPH) macrophage Ca2+-independent form 440200, 440201
Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.39nitric-oxide synthase (NADPH) macrophage cytokine-activated 440192, 440200, 440219
Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.39nitric-oxide synthase (NADPH) macrophage in liver, lung, kidney, isoform II 440226
Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.39nitric-oxide synthase (NADPH) macrophage inducible enzyme 671728
Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.39nitric-oxide synthase (NADPH) macrophage iNOS 687358
Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.39nitric-oxide synthase (NADPH) macrophage iNOS is the predominant isozyme in macrophages 695853
Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.39nitric-oxide synthase (NADPH) macrophage NOS2 701646
Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.39nitric-oxide synthase (NADPH) macrophage RAW 264.7 cells 440219, 440221, 440222, 440223, 440225, 440236, 440238
Show all pathways known for 1.14.13.9Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.9kynurenine 3-monooxygenase macrophage - 763915, 764034
Show all pathways known for 1.14.13.9Display the word mapDisplay the reaction diagram Show all sequences 1.14.13.9kynurenine 3-monooxygenase macrophage in first and second trimester of the placenta, within the fetal villus 660112
Show all pathways known for 1.14.14.18Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.18heme oxygenase (biliverdin-producing) macrophage - 684920, 685498, 686078, 688061, 688881, 705614, 733904
Show all pathways known for 1.14.14.18Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.18heme oxygenase (biliverdin-producing) macrophage peritoneal, alveolar 438244
Display the word mapDisplay the reaction diagram Show all sequences 1.14.14.2925/26-hydroxycholesterol 7alpha-hydroxylase macrophage bone marrow-derived 699414
Show all pathways known for 1.14.15.15Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.15cholestanetriol 26-monooxygenase macrophage - 703582
Show all pathways known for 1.14.15.18Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.18calcidiol 1-monooxygenase macrophage - 675057, 675686
Show all pathways known for 1.14.15.18Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.18calcidiol 1-monooxygenase macrophage expression of 1alpha-hydroxylase is intimately associated with toll-like receptor, TLR, recognition of pathogens in macrophages 712885
Show all pathways known for 1.14.15.18Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.18calcidiol 1-monooxygenase macrophage monocyte-derived 688675
Display the word mapDisplay the reaction diagram Show all sequences 1.14.16.5alkylglycerol monooxygenase macrophage - 746303
Display the word mapDisplay the reaction diagram Show all sequences 1.14.99.38cholesterol 25-monooxygenase macrophage - -, 699414, 700999, 715833, 744738
Display the word mapDisplay the reaction diagram Show all sequences 1.14.99.38cholesterol 25-monooxygenase macrophage testicular 658244, 658246
Display the word mapDisplay the reaction diagram Show all sequences 1.14.99.38cholesterol 25-monooxygenase macrophage testicular, 10-day-old animals have the highest steady-state levels of message 658245
Show all pathways known for 1.15.1.1Display the word mapDisplay the reaction diagram Show all sequences 1.15.1.1superoxide dismutase macrophage - 685864
Show all pathways known for 1.15.1.1Display the word mapDisplay the reaction diagram Show all sequences 1.15.1.1superoxide dismutase macrophage peritoneal macrophages exposed to He-Ne laser radiation. Changes in the activity of superoxide dismutase as well as the formation of nitric oxide and peroxynitrite depend to a large extent on the laser radiation dose. Activation of enzyme at low radiation doses is accompanied by nitric oxide level increase without changes in peroxynitrite. Enhanced laser radiation doses inhibit the enzyme 672292
Show all pathways known for 1.16.3.1Display the word mapDisplay the reaction diagram Show all sequences 1.16.3.1ferroxidase macrophage - 438021
Display the word mapDisplay the reaction diagram Show all sequences 1.17.3.2xanthine oxidase macrophage alveolar macrophages purified from the lung by lavage, and interstitial macrophages. Inflammatory cells express high levels of XOR activity, while in resident alveolar macrophage the enzyme content is extremely low prior to cytokine insufflation -, 715663
Show all pathways known for 1.2.1.104Display the reaction diagram Show all sequences 1.2.1.104pyruvate dehydrogenase system macrophage - 763502
Show all pathways known for 1.2.1.13Display the word mapDisplay the reaction diagram Show all sequences 1.2.1.13glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) macrophage peritoneal 288005
Display the word mapDisplay the reaction diagram Show all sequences 1.2.1.36retinal dehydrogenase macrophage hepatic 743375
Show all pathways known for 1.2.4.1Display the word mapDisplay the reaction diagram Show all sequences 1.2.4.1pyruvate dehydrogenase (acetyl-transferring) macrophage - 763502
Show all pathways known for 1.3.1.21Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.217-dehydrocholesterol reductase macrophage - 763129
Show all pathways known for 1.3.1.24Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.24biliverdin reductase macrophage - 673797, 698922, 740486, 740549
Show all pathways known for 1.3.1.24Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.24biliverdin reductase macrophage increased expression in macrophages of primary spontaneous pneumothorax of smokers compared to non-smokers 713359
Show all pathways known for 1.3.1.24Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.24biliverdin reductase macrophage lung 713359
Show all pathways known for 1.4.3.2Display the word mapDisplay the reaction diagram Show all sequences 1.4.3.2L-amino-acid oxidase macrophage - 726320
Show all pathways known for 1.4.3.2Display the word mapDisplay the reaction diagram Show all sequences 1.4.3.2L-amino-acid oxidase macrophage immunostaining in macrophages associated with non small-cell lung carcinomas, mesotheliomas, colorectal carcinomas and testicular germ cell tumors, positive staining in germinal centers of reactive lymph nodes and hyperplastic tonsils, and in the spleen 699933
Show all pathways known for 1.5.3.16Display the word mapDisplay the reaction diagram Show all sequences 1.5.3.16spermine oxidase macrophage - 725128, 741582
Show all pathways known for 1.6.1.2Display the word mapDisplay the reaction diagram Show all sequences 1.6.1.2NAD(P)+ transhydrogenase (Re/Si-specific) macrophage bone marrow-derived, Nnt mRNA and protein are expressed in resting macrophages and down-regulated in response to inflammatory stimuli such as lipopolysaccharide. Nnt mRNA and protein expression are further repressed in fully activated macrophages 724953
Show all pathways known for 1.6.1.2Display the word mapDisplay the reaction diagram Show all sequences 1.6.1.2NAD(P)+ transhydrogenase (Re/Si-specific) macrophage bone marrow-derived, Nnt mRNA and protein are expressed in resting macrophages and down-regulated in response to inflammatory stimuli such as lipopolysaccharide. Nnt mRNA and protein expression are repressed in fully activated macrophages 724953
Display the word mapDisplay the reaction diagram Show all sequences 1.6.3.1NAD(P)H oxidase (H2O2-forming) macrophage - 742310, 743287
Display the word mapDisplay the reaction diagram Show all sequences 1.6.3.1NAD(P)H oxidase (H2O2-forming) macrophage alveolar macrophages. Inhibition of NAD(P)H oxidase by apocynin results in down-regulation of arginase 686562
Display the word mapDisplay the reaction diagram Show all sequences 1.6.3.1NAD(P)H oxidase (H2O2-forming) macrophage Burkholderia cenocepacia resides in macrophage vacuoles displaying an altered recruitment of the NADPH oxidase complex at the phagosomal membrane 700052
Display the word mapDisplay the reaction diagram Show all sequences 1.6.3.1NAD(P)H oxidase (H2O2-forming) macrophage isoforms NOX2 and NOX4 742567
Show all pathways known for 1.6.5.2Display the word mapDisplay the reaction diagram Show all sequences 1.6.5.2NAD(P)H dehydrogenase (quinone) macrophage enzyme is highly upregulated in active and chronic multiple sclerosis lesions, particularly in hypertrophic astrocytes and myelin-laden macrophages 673798
Show all pathways known for 1.8.1.7Display the word mapDisplay the reaction diagram Show all sequences 1.8.1.7glutathione-disulfide reductase macrophage - 690144
Show all pathways known for 1.8.4.12Display the word mapDisplay the reaction diagram Show all sequences 1.8.4.12peptide-methionine (R)-S-oxide reductase macrophage highly expressed in immune-activated macrophages 765804
Display the word mapDisplay the reaction diagram Show all sequences 1.8.4.2protein-disulfide reductase (glutathione) macrophage - 394863
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.319type I protein arginine methyltransferase macrophage - 756732
Show all pathways known for 2.1.1.355Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.355[histone H3]-lysine9 N-trimethyltransferase macrophage - 755432
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.360[histone H3]-lysine79 N-trimethyltransferase macrophage - 753191
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.364[histone H3]-lysine4 N-methyltransferase macrophage - 704436
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.366[histone H3]-N6,N6-dimethyl-lysine9 N-methyltransferase macrophage - 755432
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.63methylated-DNA-[protein]-cysteine S-methyltransferase macrophage - 701644
Show all pathways known for 2.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.2.1.1transketolase macrophage at the lesion border 694176
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.147glycerophospholipid arachidonoyl-transferase (CoA-independent) macrophage - 16268
Display the reaction diagram Show all sequences 2.3.1.148glycerophospholipid acyltransferase (CoA-dependent) macrophage - 16278
Show all pathways known for 2.3.1.15Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.15glycerol-3-phosphate 1-O-acyltransferase macrophage bone marrow-derived macrophages -, 756014
Show all pathways known for 2.3.1.23Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.231-acylglycerophosphocholine O-acyltransferase macrophage - 704461, 736546, 756102
Show all pathways known for 2.3.1.23Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.231-acylglycerophosphocholine O-acyltransferase macrophage primary peripheral blood macrophages 735571
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.26sterol O-acyltransferase macrophage - 486696, 486703, 684800, 702552, 702650, 703975, 736792
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.26sterol O-acyltransferase macrophage ACAT1, villus 486708
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.26sterol O-acyltransferase macrophage loss of ACAT activity in macrophages, either by pharmacological inhibition or by genetic knockout of ACAT-1, results in reduced induction of apoptosis in response to 7-ketocholesterol or oxidized low density lipoproteins. The apoptotic signal generated in macrophages by ACAT may be an arachidonyl oxysterol 675261
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.26sterol O-acyltransferase macrophage monocyte-derived macrophage 684780
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.26sterol O-acyltransferase macrophage relative high level of mRNA 486703
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.48histone acetyltransferase macrophage - -, 702855
Results 1 - 100 of 465 > >>
download as CSV
download all results as CSV