EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.102 | 3-dehydrosphinganine reductase |
leukocyte |
pheripheral blood, low expression |
656256 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
leukocyte |
- |
760868 |
1.1.1.205 | IMP dehydrogenase |
leukocyte |
- |
705494 |
1.1.1.205 | IMP dehydrogenase |
leukocyte |
type I isoform is prevalent |
705494 |
1.1.1.315 | 11-cis-retinol dehydrogenase |
leukocyte |
9% mRNA expression of Rdh5 compared to liver |
690797 |
1.1.1.34 | hydroxymethylglutaryl-CoA reductase (NADPH) |
leukocyte |
- |
286571 |
1.1.1.35 | 3-hydroxyacyl-CoA dehydrogenase |
leukocyte |
- |
699171 |
1.1.1.49 | glucose-6-phosphate dehydrogenase (NADP+) |
leukocyte |
- |
655123 |
1.1.1.8 | glycerol-3-phosphate dehydrogenase (NAD+) |
leukocyte |
also other blood components |
287331 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
leukocyte |
- |
671713, 671833 |
1.11.1.7 | peroxidase |
leukocyte |
- |
712063 |
1.11.1.9 | glutathione peroxidase |
leukocyte |
- |
685441 |
1.11.2.2 | myeloperoxidase |
leukocyte |
- |
439758, 672240, 686875, 688194, 689811, 711124, 711125, 711274, 711881, 711882, 711998, 712327, 712342, 713543, 724229, 724461, 742569 |
1.11.2.2 | myeloperoxidase |
leukocyte |
polymorphonuclear |
439743 |
1.13.11.11 | tryptophan 2,3-dioxygenase |
leukocyte |
immune cells express high amount of the enzyme (TDO2) at the peak stage of adjuvant-induced arthritis |
764385 |
1.13.11.31 | arachidonate 12-lipoxygenase |
leukocyte |
- |
-, 395399, 395400, 395403, 395404, 395406, 395407, 395408, 395409, 395410, 395425, 395426, 395428, 395429, 395431, 685330, 701926, 741573, 743324, 743718 |
1.13.11.31 | arachidonate 12-lipoxygenase |
leukocyte |
Alox15 |
684342 |
1.13.11.31 | arachidonate 12-lipoxygenase |
leukocyte |
from healthy individuals, quantitative expression analysis |
688751 |
1.13.11.31 | arachidonate 12-lipoxygenase |
leukocyte |
polymorphonuclear |
395418 |
1.13.11.33 | arachidonate 15-lipoxygenase |
leukocyte |
- |
-, 639237, 639240, 686173, 701636, 742613, 743718 |
1.13.11.33 | arachidonate 15-lipoxygenase |
leukocyte |
2 isoenzymes detected in leukocytes, the minor isoenzyme is enriched in leukocytes from an eosinophilic patient |
639243 |
1.13.11.33 | arachidonate 15-lipoxygenase |
leukocyte |
eosinophil-enriched leukocytes |
639246, 639247, 639248 |
1.13.11.33 | arachidonate 15-lipoxygenase |
leukocyte |
from healthy individuals, quantitative expression analysis |
688751 |
1.13.11.33 | arachidonate 15-lipoxygenase |
leukocyte |
peritoneal polymorphonuclear leukocytes |
639253 |
1.13.11.33 | arachidonate 15-lipoxygenase |
leukocyte |
polymorphonuclear |
639241, 639250, 639252 |
1.13.11.34 | arachidonate 5-lipoxygenase |
leukocyte |
- |
439438, 439441, 439442, 439443, 439447, 439448, 439452, 439456, 439459, 439474, 439479, 660111, 675773, 690170, 704997, 712666, 742447, 743326, 743614, 764158 |
1.13.11.34 | arachidonate 5-lipoxygenase |
leukocyte |
from healthy individuals, quantitative expression analysis |
688751 |
1.13.11.34 | arachidonate 5-lipoxygenase |
leukocyte |
peritoneal |
685571 |
1.13.11.34 | arachidonate 5-lipoxygenase |
leukocyte |
peritoneal polymorphonuclear |
439453, 439466 |
1.13.11.34 | arachidonate 5-lipoxygenase |
leukocyte |
polymorphonuclear |
439445, 439451, 439455, 439463, 439467, 439476, 686524, 688246, 689841, 741862 |
1.13.11.34 | arachidonate 5-lipoxygenase |
leukocyte |
polymorphonuclear leukocyte |
676924, 764112, 764451 |
1.13.11.5 | homogentisate 1,2-dioxygenase |
leukocyte |
- |
697403 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
leukocyte |
- |
685906 |
1.14.14.25 | cholesterol 24-hydroxylase |
leukocyte |
- |
703580 |
1.14.14.32 | 17alpha-hydroxyprogesterone deacetylase |
leukocyte |
peripheral blood leukocyte |
690654 |
1.14.14.94 | leukotriene-B4 20-monooxygenase |
leukocyte |
- |
685340, 703413 |
1.14.14.94 | leukotriene-B4 20-monooxygenase |
leukocyte |
polymorphonuclear |
390064, 390065, 390066, 390067, 390068, 390072, 674761 |
1.14.15.16 | vitamin D3 24-hydroxylase |
leukocyte |
- |
736557 |
1.14.18.9 | 4alpha-methylsterol monooxygenase |
leukocyte |
- |
727093 |
1.16.3.1 | ferroxidase |
leukocyte |
- |
438032 |
1.2.1.31 | L-aminoadipate-semialdehyde dehydrogenase |
leukocyte |
peripheral blood |
288202 |
1.2.1.31 | L-aminoadipate-semialdehyde dehydrogenase |
leukocyte |
peripheral blood leukocyte |
675897 |
1.21.99.3 | thyroxine 5-deiodinase |
leukocyte |
- |
744614 |
1.3.1.70 | DELTA14-sterol reductase |
leukocyte |
peripheral blood leukocyte, LBR |
672378 |
1.3.8.4 | isovaleryl-CoA dehydrogenase |
leukocyte |
- |
699381 |
1.3.8.6 | glutaryl-CoA dehydrogenase (ETF) |
leukocyte |
- |
391410, 688177 |
1.3.8.7 | medium-chain acyl-CoA dehydrogenase |
leukocyte |
- |
684292, 688185 |
1.3.8.8 | long-chain acyl-CoA dehydrogenase |
leukocyte |
- |
686160 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
leukocyte |
- |
687319 |
1.4.1.3 | glutamate dehydrogenase [NAD(P)+] |
leukocyte |
- |
697371 |
1.4.3.13 | protein-lysine 6-oxidase |
leukocyte |
- |
686038, 687203, 689100 |
1.4.3.2 | L-amino-acid oxidase |
leukocyte |
- |
656435 |
1.4.3.3 | D-amino-acid oxidase |
leukocyte |
- |
686020 |
1.4.3.5 | pyridoxal 5'-phosphate synthase |
leukocyte |
from peripheral blood, 0.4% of the activity in liver |
655483 |
1.5.1.15 | methylenetetrahydrofolate dehydrogenase (NAD+) |
leukocyte |
cell line 3T3, mouse embryo |
392077 |
1.5.1.15 | methylenetetrahydrofolate dehydrogenase (NAD+) |
leukocyte |
cell line TL3and TL4, EBV-transformed |
392077 |
1.5.1.20 | methylenetetrahydrofolate reductase [NAD(P)H] |
leukocyte |
- |
684473, 685893, 685988, 686240, 686310, 686329, 686835, 688057, 689031, 689166, 690181 |
1.6.2.4 | NADPH-hemoprotein reductase |
leukocyte |
polymorphonuclear |
288545 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
leukocyte |
high expression |
689034 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
leukocyte |
platelets and leukocytes from high cholesterol-fed mice exhibit elevated generation of reactive oxygen species compared to normal diet mice. Hypercholesterolemia-induced leukocyte recruitment is attenuated in Cu,Zn-superoxide dismutase transgenic, and NAD(P)H oxidase-knockout mice on high cholesterol diet. Platelets from NAD(P)H oxidase-knockout mice on high cholesterol diet exhibit low levels of adhesion comparable to those of wild-type on normal diet. Overexpression of Cu,Zn-superoxide dismutase or, to a lesser extent, NAD(P)H oxidase subunit gp91 deficiency restores arteriolar vasorelaxation responses toward normal diet wild-type levels |
686869 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
leukocyte |
polymorphonuclear leukocyte |
684872 |
1.6.5.10 | NADPH dehydrogenase (quinone) |
leukocyte |
for genotyping |
690177 |
1.6.5.2 | NAD(P)H dehydrogenase (quinone) |
leukocyte |
- |
689279 |
1.6.5.2 | NAD(P)H dehydrogenase (quinone) |
leukocyte |
for genotyping |
689130 |
1.6.5.2 | NAD(P)H dehydrogenase (quinone) |
leukocyte |
no correlation between NQO1 activity in rectal biopsies and NQO1 activity in total leukocytes. No correlation between total leukocyte and lymphocyte NQO1 activity |
689279 |
1.6.5.4 | monodehydroascorbate reductase (NADH) |
leukocyte |
- |
392737 |
1.7.1.7 | GMP reductase |
leukocyte |
expressed at low levels |
394294 |
1.8.1.7 | glutathione-disulfide reductase |
leukocyte |
- |
394708 |
1.8.3.1 | sulfite oxidase |
leukocyte |
perpheral blood, little expression |
657738 |
1.8.4.12 | peptide-methionine (R)-S-oxide reductase |
leukocyte |
polymorphonuclear |
394098 |
1.8.4.2 | protein-disulfide reductase (glutathione) |
leukocyte |
- |
394810 |
1.8.5.4 | bacterial sulfide:quinone reductase |
leukocyte |
- |
742246 |
2.1.1.20 | glycine N-methyltransferase |
leukocyte |
GNMT is expressed in the epithelium of the colon under normal conditions, and with dextran sulfate sodium treatment, its expression is predominant in infiltrated leukocytes of lesions |
734396 |
2.1.1.355 | [histone H3]-lysine9 N-trimethyltransferase |
leukocyte |
- |
704544 |
2.1.1.6 | catechol O-methyltransferase |
leukocyte |
leukocyte exposure to morphine down-regulates catechol-O-methyl transferase and CYP2D6 by approximately 50% compared with control values. Exposure of white blood cells to 0.001 mM S-nitroso-N-acetyl-DL-penicillamine, a nitric oxide donor, reduces the expression of CYP2D6 and COMT. Prior naloxone (0.001 mM) or N-nitro-L-arginine methyl ester (0.1 mM) addition abrogates down-regulating activity of morphine, demonstrating morphine is initiating its actions via stimulating constitutive NO synthase derived NO release via the mu3 opiate receptor splice variant |
684238 |
2.1.1.61 | tRNA 5-(aminomethyl)-2-thiouridylate-methyltransferase |
leukocyte |
low level |
671744 |
2.1.1.67 | thiopurine S-methyltransferase |
leukocyte |
- |
485522 |
2.1.1.67 | thiopurine S-methyltransferase |
leukocyte |
peripheral blood leukocytes |
684267, 688807 |
2.1.1.67 | thiopurine S-methyltransferase |
leukocyte |
TPMT genotyping |
686161 |
2.1.1.72 | site-specific DNA-methyltransferase (adenine-specific) |
leukocyte |
- |
719373 |
2.2.1.1 | transketolase |
leukocyte |
- |
486004, 486026 |
2.3.1.149 | Platelet-activating factor acetyltransferase |
leukocyte |
- |
756321 |
2.3.1.20 | diacylglycerol O-acyltransferase |
leukocyte |
- |
486505 |
2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
leukocyte |
- |
705001 |
2.3.1.45 | N-acetylneuraminate 7-O(or 9-O)-acetyltransferase |
leukocyte |
- |
719565 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
leukocyte |
- |
671597, 705206 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
leukocyte |
expressed in |
688005 |
2.3.1.67 | 1-alkylglycerophosphocholine O-acetyltransferase |
leukocyte |
- |
487383, 703250, 736050, 756321, 758268 |
2.3.1.78 | heparan-alpha-glucosaminide N-acetyltransferase |
leukocyte |
deficiency on leukocytes from patients with Sanfillippo syndrome type C |
487507 |
2.3.1.97 | glycylpeptide N-tetradecanoyltransferase |
leukocyte |
- |
719244 |
2.3.2.2 | gamma-glutamyltransferase |
leukocyte |
- |
755785 |
2.3.3.10 | hydroxymethylglutaryl-CoA synthase |
leukocyte |
- |
720426 |
2.3.3.8 | ATP citrate synthase |
leukocyte |
- |
488219 |
2.4.1.102 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase |
leukocyte |
- |
722983 |
2.4.1.102 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase |
leukocyte |
leukocyte-type isozyme |
735958 |
2.4.1.102 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase |
leukocyte |
peripheral blood |
638286 |
2.4.1.11 | glycogen(starch) synthase |
leukocyte |
- |
488420, 488421, 488424 |
2.4.1.122 | N-acetylgalactosaminide beta-1,3-galactosyltransferase |
leukocyte |
- |
638326 |
2.4.1.145 | alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase |
leukocyte |
isoform GnT-IVa is highly restricted in gastrointestinal organs and peripheral blood leukocytes |
723792 |
2.4.1.148 | acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase |
leukocyte |
- |
722983 |