Any feedback?
Please rate this page
(search_result.php)
(0/150)

BRENDA support

Refine search

Search Source Tissue

show results
Don't show organism specific information (fast!)
Search organism in taxonomic tree (slow, choose "exact" as search mode, e.g. "mammalia" for rat,human,monkey,...)
(Not possible to combine with the first option)
Refine your search
Show additional data
do not include text mining results
include AMENDA results (Automatic Mining of Enzyme Data)

Search term: lens

Results 1 - 98 of 98
download as CSV
download all results as CSV
EC Number Recommended Name Source Tissue Commentary Reference
Show all pathways known for 1.1.1.14Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.14L-iditol 2-dehydrogenase lens - 285895, 285898, 655289, 668225
Show all pathways known for 1.1.1.179Display the reaction diagram Show all sequences 1.1.1.179D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) lens - 286124, 286128
Show all pathways known for 1.1.1.188Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.188prostaglandin-F synthase lens - 389458
Show all pathways known for 1.1.1.19Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.19glucuronate reductase lens - 286146
Show all pathways known for 1.1.1.2Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.2alcohol dehydrogenase (NADP+) lens - -, 286168, 286180, 286182, 286219, 286220, 738840
Show all pathways known for 1.1.1.21Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.21aldose reductase lens - 286240, 286243, 286245, 286247, 286250, 286256, 286261, 654957, 656089, 667224, 667331, 667349, 667923, 667931, 669794, 670121, 685456, 685465, 685544, 689107, 695930, 696708, 699247, 699641, 699743, 711353, 711356, 711427, 711458, 713242, 723017, 737604, 737763, 738833, 739379, 739481, 760690, 761282, 761950
Show all pathways known for 1.1.1.21Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.21aldose reductase lens ALR2 711452
Show all pathways known for 1.1.1.21Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.21aldose reductase lens calf 738164
Show all pathways known for 1.1.1.21Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.21aldose reductase lens cultured epithelial cells 668511, 668515
Show all pathways known for 1.1.1.21Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.21aldose reductase lens cultured, healthy and diabetic lens 668511
Show all pathways known for 1.1.1.21Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.21aldose reductase lens isoform ALR2 685547, 761025
Show all pathways known for 1.1.1.21Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.21aldose reductase lens of diabetic rats 669791
Show all pathways known for 1.1.1.27Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.27L-lactate dehydrogenase lens - 286464
Show all pathways known for 1.1.1.44Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.44phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) lens - 286897
Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.45L-gulonate 3-dehydrogenase lens - 286146, 669147, 712765
Show all pathways known for 1.1.1.95Display the word mapDisplay the reaction diagram Show all sequences 1.1.1.95phosphoglycerate dehydrogenase lens epithelium 654940
Show all pathways known for 1.13.11.52Display the word mapDisplay the reaction diagram Show all sequences 1.13.11.52indoleamine 2,3-dioxygenase lens enzyme activity is detected in all lenses ranging from 26 to 80 years and there are no clear relationship of IDO activity with age 657494
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.2procollagen-proline 4-dioxygenase lens embryo, lowest enzyme activity 439200
Show all pathways known for 1.14.15.15Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.15cholestanetriol 26-monooxygenase lens - 713175
Show all pathways known for 1.2.1.3Display the word mapDisplay the reaction diagram Show all sequences 1.2.1.3aldehyde dehydrogenase (NAD+) lens - 348708, 348709, 693311, 711635
Show all pathways known for 1.2.1.3Display the word mapDisplay the reaction diagram Show all sequences 1.2.1.3aldehyde dehydrogenase (NAD+) lens tissue with highest content 655948
Display the word mapDisplay the reaction diagram Show all sequences 1.2.1.36retinal dehydrogenase lens - 390272, 654700, 655948
Display the word mapDisplay the reaction diagram Show all sequences 1.3.1.20trans-1,2-dihydrobenzene-1,2-diol dehydrogenase lens - 286128, 349240, 349254, 686023
Display the word mapDisplay the reaction diagram Show all sequences 1.4.3.13protein-lysine 6-oxidase lens determination of LOX activity and expression in donor ocular tissues 698383
Show all pathways known for 1.5.1.2Display the word mapDisplay the reaction diagram Show all sequences 1.5.1.2pyrroline-5-carboxylate reductase lens - 392112
Display the word mapDisplay the reaction diagram Show all sequences 1.5.1.25thiomorpholine-carboxylate dehydrogenase lens - 741580
Display the word mapDisplay the reaction diagram Show all sequences 1.6.5.4monodehydroascorbate reductase (NADH) lens - 392752, 655510
Display the word mapDisplay the reaction diagram Show all sequences 1.6.5.4monodehydroascorbate reductase (NADH) lens high activity 392752
Display the word mapDisplay the reaction diagram Show all sequences 1.6.5.4monodehydroascorbate reductase (NADH) lens weak activity 392752
Display the word mapDisplay the reaction diagram Show all sequences 1.6.5.5NADPH:quinone reductase lens - 14077, 14079, 14082, 14083, 14084, 14086, 14087, 14088, 14089, 697208, 697701, 742325
Display the word mapDisplay the reaction diagram Show all sequences 1.6.5.5NADPH:quinone reductase lens cortex 14081
Display the word mapDisplay the reaction diagram Show all sequences 1.6.5.5NADPH:quinone reductase lens in animals homozygous for the cataract phenotype the normal zeta-crystallin polypeptide is absent from the lens -, 697795
Show all pathways known for 1.8.1.7Display the word mapDisplay the reaction diagram Show all sequences 1.8.1.7glutathione-disulfide reductase lens - 673194
Show all pathways known for 1.8.1.7Display the word mapDisplay the reaction diagram Show all sequences 1.8.1.7glutathione-disulfide reductase lens glutathione reductase plays a key role in maintaining thiol groups in the lens, and its activity decreases with aging and cataract formation. The glutathione reductase activity in the cortex and nucleus of the cataractous lenses is significantly lower than that of the aged clear lenses. The highest activity in the cortex is observed in the clear aged lenses. The combination of thioredoxin and thioredoxin reductase revives the activity of glutathione reductase from both the cortex and nucleus of aged clear lenses. In cataract lenses (grade II and grade IV), there is a statistically significant recovery of glutathione reductase activity in the cortex, but not in the nucleus. No recovery is observed when thioredoxin or thioredoxin reductase are used separately. alpha-Crystallin successfully revives glutathione reductase activity in the cortex of cataract grade II lenses, but not in the nucleus. The combination of alpha-crystallin and thioredoxin/thioredoxin reductase gives a further increase of activity. Thioltransferase alone revives some of the glutathione reductase activity but together with the thioredoxin/thioredoxin reductase system gives no statistically significant enhancement of glutathione reductase activity 686259
Show all pathways known for 1.8.1.7Display the word mapDisplay the reaction diagram Show all sequences 1.8.1.7glutathione-disulfide reductase lens the combination of thioredioxin and thioredoxin reductase revives the activity of glutathione reductase from both the cortex and nucleus of aged clear lenses. In cataract lenses (grade II and grade IV) there is a statistically significant recovery of glutathione reductase activity in the cortex, but not in the nucleus. alpha-Crystallin successfully revives glutathione reductase activity in the cortex of cataract grade II lenses, but not in the nucleus. the combination of alpha-crystallin and thioredoxin/thioredoxin reductase gives a further increase in activity. Both disulfide bond formation and protein unfolding are responsible for glutathione inactivation 686259
Display the reaction diagram Show all sequences 1.8.4.11peptide-methionine (S)-S-oxide reductase lens - 660380, 686598, 696438
Show all pathways known for 1.8.4.12Display the word mapDisplay the reaction diagram Show all sequences 1.8.4.12peptide-methionine (R)-S-oxide reductase lens epithelia and fibers, isozymes MsrB1 or selenoprotein R, MsrB2 or CBS-1, and MsrB3, differential expression patterns of isozymes, overview 669008
Display the word mapDisplay the reaction diagram Show all sequences 1.8.4.2protein-disulfide reductase (glutathione) lens - 394810
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.296methyltransferase cap2 lens - 756633
Show all pathways known for 2.1.1.5Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.5betaine-homocysteine S-methyltransferase lens - 441244
Show all pathways known for 2.1.1.5Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.5betaine-homocysteine S-methyltransferase lens represents 0.5-10% of the total protein, presence of BHMT can be related to its role in betaine removal when osmotic stress disappears, a key process, since osmotic swelling is a major factor in the development of some types of cataracts 673003
Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.77protein-L-isoaspartate(D-aspartate) O-methyltransferase lens - 485597
Display the reaction diagram Show all sequences 2.3.1.33histidine N-acetyltransferase lens - 486793, 735700
Display the reaction diagram Show all sequences 2.3.1.33histidine N-acetyltransferase lens the amount of enzyme activity is related to starvation and feeding of the fish 486794
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.48histone acetyltransferase lens expressed in embryonic lens. The lens-specific chromatin domain contains both promoter localized CBP on the background of locus spread-presence of CBP and p300 688356
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.13protein-glutamine gamma-glutamyltransferase lens - 487827, 487867, 686596
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.13protein-glutamine gamma-glutamyltransferase lens cortex 487843
Show all pathways known for 2.3.2.2Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.2gamma-glutamyltransferase lens very low activity 487911
Display the word mapDisplay the reaction diagram Show all sequences 2.3.2.27RING-type E3 ubiquitin transferase lens developing lens 692490
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.206lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase lens the enzyme is expressedin two distinct phases during the zebrafish embryogenesis. The early phase extends from late blastulation to the completion of epiboly, during which the expression occurs in the superficial layer of the embryos. The second phase of expression starts during mid-segmentation and persists until day 3, during which the expression occurs prominently in the developing lens. Hedgehog signaling is required for the Lc3 synthase expression in embryonic lens 658505
Show all pathways known for 2.5.1.18Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.18glutathione transferase lens - 722273
Show all pathways known for 2.5.1.6Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.6methionine adenosyltransferase lens - 639039
Show all pathways known for 2.7.1.11Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.116-phosphofructokinase lens calf 640421
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.171protein-fructosamine 3-kinase lens - 738073, 761600
Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.172protein-ribulosamine 3-kinase lens highest levels of expression in bone marrow, brain, spleen, kidney, and lens 708296
Show all pathways known for 2.7.1.32Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.32choline kinase lens - 641381
Show all pathways known for 2.7.1.82Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.82ethanolamine kinase lens - 641381
Show all pathways known for 2.7.4.3Display the word mapDisplay the reaction diagram Show all sequences 2.7.4.3adenylate kinase lens - 642566
Display the word mapDisplay the reaction diagram Show all sequences 2.8.2.8[heparan sulfate]-glucosamine N-sulfotransferase lens gene Ndst1 is expressed during lens development, in lens epithelium, strong expression occurs in both the lens placode and in the optic vesicle in mouse embryos at stage E9.5, overview 673255
Display the word mapDisplay the reaction diagram Show all sequences 3.1.22.1deoxyribonuclease II lens - 680266, 697574
Display the word mapDisplay the reaction diagram Show all sequences 3.1.22.1deoxyribonuclease II lens during lens cell differentiation 696131
Display the word mapDisplay the reaction diagram Show all sequences 3.1.22.1deoxyribonuclease II lens fiber cells, epithelium 134284
Display the word mapDisplay the reaction diagram Show all sequences 3.1.22.1deoxyribonuclease II lens specific expression of isoform DNase IIbeta 679773
Show all pathways known for 3.1.3.2Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.2acid phosphatase lens - 134703
Display the word mapDisplay the reaction diagram Show all sequences 3.1.3.48protein-tyrosine-phosphatase lens LMW-PTP is the predominant tyrosine phosphatase expressed in lens 692322
Show all pathways known for 3.1.8.1Display the word mapDisplay the reaction diagram Show all sequences 3.1.8.1aryldialkylphosphatase lens eye lens epithelium, PON1 692441
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.166heparanase lens - 714922
Display the word mapDisplay the reaction diagram Show all sequences 3.4.11.1leucyl aminopeptidase lens - 25, 35862, 35908, 649773, 650856, 664129, 665075, 665306, 679846, 95189, 95190, 95192, 95197, 95200, 95201, 95210, 95211, 95212, 95213, 95214, 95216, 95217, 95219, 95220
Display the word mapDisplay the reaction diagram Show all sequences 3.4.13.5Xaa-methyl-His dipeptidase lens cortex, concentrated in the capsule at levels up to 3 mg/ml 36080
Display the word mapDisplay the reaction diagram Show all sequences 3.4.14.2dipeptidyl-peptidase II lens - 95247
Display the word mapDisplay the reaction diagram Show all sequences 3.4.14.4dipeptidyl-peptidase III lens - 36185
Display the word mapDisplay the reaction diagram Show all sequences 3.4.19.1acylaminoacyl-peptidase lens - 95263, 95265, 95268
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.26prolyl oligopeptidase lens - 653873, 81352
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.5thrombin lens human capsular bag model 669010
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.52calpain-1 lens - 707136
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.52calpain-1 lens calpain 1 is most abundant in cells near the lens surface 709015
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.52calpain-1 lens from Shumiya cataract animals 644000
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.53calpain-2 lens - 667378
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.53calpain-2 lens derived from Shumiya cataract animals 644000
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.54calpain-3 lens calpain 3 or its isoforms is necessary for formation of the nuclear cataract that is observed in the alpha3Cx46-/- lens. In the absence of the CAPN3 gene, the formation of a cataract is delayed, and its appearance is changed to a more diffuse, pulverulent type 680264
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.59caspase-6 lens - 669243
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B30calpain 10 lens - 648105
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B30calpain 10 lens lens epithelium, outer fiber cells of lens 648105
Display the word mapDisplay the reaction diagram Show all sequences 3.4.23.45memapsin 1 lens - -, 638898
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.35gelatinase B lens - 717349
Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.15aspartoacylase lens - 667777
Display the word mapDisplay the reaction diagram Show all sequences 3.6.5.6tubulin GTPase lens lens epithelial cell 686631
Show all pathways known for 4.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.1carbonic anhydrase lens - 680179
Show all pathways known for 4.2.1.3Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.3aconitate hydratase lens epithelium 649551
Show all pathways known for 4.3.2.1Display the word mapDisplay the reaction diagram Show all sequences 4.3.2.1argininosuccinate lyase lens - 34436, 34437, 34442, 34443, 34444, 34445, 34447
Show all pathways known for 4.4.1.5Display the word mapDisplay the reaction diagram Show all sequences 4.4.1.5lactoylglutathione lyase lens GLOI is mainly localized in the anterior epithelium but the enzyme is diffusely present in outer cortical and nuclear regions of the human lens 707602
Show all pathways known for 4.4.1.5Display the word mapDisplay the reaction diagram Show all sequences 4.4.1.5lactoylglutathione lyase lens glyoxalase I activity and mRNA levels are elevated in diabetic lenses 681891
Display the word mapDisplay the reaction diagram Show all sequences 5.3.2.1phenylpyruvate tautomerase lens - 2873
Show all pathways known for 5.4.99.7Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.7Lanosterol synthase lens - 662517
Show all pathways known for 5.4.99.7Display the word mapDisplay the reaction diagram Show all sequences 5.4.99.7Lanosterol synthase lens in lens epithelial layer and shallow cortex layer 749433
Show all pathways known for 6.3.2.2Display the word mapDisplay the reaction diagram Show all sequences 6.3.2.2glutamate-cysteine ligase lens - 1131, 1137, 649263
Show all pathways known for 7.1.1.9Display the word mapDisplay the reaction diagram Show all sequences 7.1.1.9cytochrome-c oxidase lens - 692222
Display the word mapDisplay the reaction diagram Show all sequences 7.2.2.13Na+/K+-exchanging ATPase lens - 246966, 711941
Results 1 - 98 of 98
download as CSV
download all results as CSV