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Search term: hepatoma cell line

Results 1 - 27 of 27
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EC Number Recommended Name Source Tissue Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.16peptide-aspartate beta-dioxygenase hepatoma cell line - 742626, 743379, 743882
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.16peptide-aspartate beta-dioxygenase hepatoma cell line increased expression of aspartate beta-hydroxylase in hepatocellular carcinoma tissues is associated with tumor invasiveness and a worse prognosis. Aspartate beta-hydroxylase overexpression in hepatocellular carcinoma tissues is correlated with decreased copy numbers of displacement loop (D-loop) and NADH dehydrogenase subunit 1 and enhanced D-loop mutation, suggesting the disrupted mitochondrial DNA (mtDNA) stability. The reduced mtDNA copy numbers are associated with aggressive clinicopathological features of hepatocellular carcinoma. The loss of mtDNA integrity induced by enforced expression of Aspartate beta-hydroxylase is accompanied with mitochondrial dysfunction, which is characterized by the aberrant mitochondrial membrane potential, decreased ATP generation and enhanced reactive oxygen species. The enzyme interacts with histone H2A member X. Overexpression of aspartate beta-hydroxylase diminishes the interaction between histone H2A member X and mitochondrial transcription factor A (mtTFA), an important DNA-binding protein for mtDNA replication, which then reduced the binding of mtTFA to D-loop region. Overexpression of aspartate beta-hydroxylase disrupts the mtDNA integrity through H2AX-mtTFA signal, thereby affecting mitochondrial functions in hepatocellular carcinoma 743376
Display the word mapDisplay the reaction diagram Show all sequences 1.14.11.18phytanoyl-CoA dioxygenase hepatoma cell line - 285272
Show all pathways known for 1.14.15.3Display the word mapDisplay the reaction diagram Show all sequences 1.14.15.3alkane 1-monooxygenase hepatoma cell line - 673653
Show all pathways known for 1.4.3.3Display the word mapDisplay the reaction diagram Show all sequences 1.4.3.3D-amino-acid oxidase hepatoma cell line 101L cell 697313
Show all pathways known for 1.5.1.2Display the word mapDisplay the reaction diagram Show all sequences 1.5.1.2pyrroline-5-carboxylate reductase hepatoma cell line full-length sequence is amplified from a hepatoma cell line cDNA library 676969
Show all pathways known for 2.1.1.5Display the word mapDisplay the reaction diagram Show all sequences 2.1.1.5betaine-homocysteine S-methyltransferase hepatoma cell line hyperosmolarity (405 mosmol/l) suppresses Bhmt mRNA expression whereas hypoosmotic (205 mosmol/l) conditions induce Bhmt mRNA expression. Like hyperosmotic NaCl, hyperosmotic raffinose but not hyperosmotic urea suppresses Bhmt mRNA expression. Osmosensitivity of Bhmt mRNA expression is impaired by inhibitors of tyrosine kinases and cyclic nucleotide-dependent kinases 671242
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.144beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase hepatoma cell line 7721 cell 638226
Display the word mapDisplay the reaction diagram Show all sequences 2.5.1.26alkylglycerone-phosphate synthase hepatoma cell line the enzyme is upregulated in multiple types of cancer cells and primary tumors 737578
Show all pathways known for 2.7.1.1Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.1hexokinase hepatoma cell line AS-30D, highly glycolytic tumor cells 640210
Show all pathways known for 2.7.1.30Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.30glycerol kinase hepatoma cell line HaIIE (ATCC) 705749
Show all pathways known for 2.7.1.32Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.32choline kinase hepatoma cell line Hepa-1 685337
Show all pathways known for 2.7.1.36Display the word mapDisplay the reaction diagram Show all sequences 2.7.1.36mevalonate kinase hepatoma cell line cell line PLC/PRF/5 641446
Display the word mapDisplay the reaction diagram Show all sequences 2.7.10.2non-specific protein-tyrosine kinase hepatoma cell line PLC cell 691651
Display the word mapDisplay the reaction diagram Show all sequences 2.7.11.2[pyruvate dehydrogenase (acetyl-transferring)] kinase hepatoma cell line The human liver cancer cell line HepG3B was obtained from the cell bank of the Institute of Biochemistry and Cell Biology 761575
Show all pathways known for 2.7.4.6Display the word mapDisplay the reaction diagram Show all sequences 2.7.4.6nucleoside-diphosphate kinase hepatoma cell line Novikoff 642661
Show all pathways known for 2.8.3.5Display the word mapDisplay the reaction diagram Show all sequences 2.8.3.53-oxoacid CoA-transferase hepatoma cell line H1e human hepatoma cell line, but no detection in normal hepatocytes, HepG2 hepatoma cells and liver tissues 695186
Display the word mapDisplay the reaction diagram Show all sequences 3.1.4.1phosphodiesterase I hepatoma cell line PLC/ PRF/5 human hepatoma 208356
Display the word mapDisplay the reaction diagram Show all sequences 3.2.1.207mannosyl-oligosaccharide alpha-1,3-glucosidase hepatoma cell line - 136899
Display the word mapDisplay the reaction diagram Show all sequences 3.4.21.68t-Plasminogen activator hepatoma cell line transformed 29575
Display the word mapDisplay the reaction diagram Show all sequences 3.4.24.35gelatinase B hepatoma cell line - 697085
Display the word mapDisplay the reaction diagram Show all sequences 3.5.1.114N-acyl-aromatic-L-amino acid amidohydrolase hepatoma cell line AA3 expression in the hepatocellular carcinoma cell lines is 5 to 20 times greater than in normal primary hepatocytes 754228
Show all pathways known for 4.1.1.22Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.22histidine decarboxylase hepatoma cell line - 693822
Show all pathways known for 4.1.1.32Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.32phosphoenolpyruvate carboxykinase (GTP) hepatoma cell line H4IIEC3 cells, mRNA is 5-10fold elevated in cells cultured at high density compared to low density, KRC-7 cells, an H4IIEC3 subclone, are much more sensitive to growth arrest than its parental cell line 649586
Show all pathways known for 4.1.1.32Display the word mapDisplay the reaction diagram Show all sequences 4.1.1.32phosphoenolpyruvate carboxykinase (GTP) hepatoma cell line Reuber H365 hepatoma cells 4364
Show all pathways known for 4.2.1.1Display the word mapDisplay the reaction diagram Show all sequences 4.2.1.1carbonic anhydrase hepatoma cell line - 700140
Show all pathways known for 6.3.5.2Display the word mapDisplay the reaction diagram Show all sequences 6.3.5.2GMP synthase (glutamine-hydrolysing) hepatoma cell line - 1384
Results 1 - 27 of 27
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