EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.13.11.63 | beta-carotene 15,15'-dioxygenase |
hepatic stellate cell |
- |
728342 |
2.3.1.135 | phosphatidylcholine-retinol O-acyltransferase |
hepatic stellate cell |
- |
720839 |
2.3.1.26 | sterol O-acyltransferase |
hepatic stellate cell |
- |
-, 736580 |
2.4.1.212 | hyaluronan synthase |
hepatic stellate cell |
- |
760190 |
2.7.11.20 | elongation factor 2 kinase |
hepatic stellate cell |
- |
723079 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
hepatic stellate cell |
- |
692554, 761093 |
2.7.7.49 | RNA-directed DNA polymerase |
hepatic stellate cell |
- |
692555 |
3.1.3.5 | 5'-nucleotidase |
hepatic stellate cell |
- |
681729 |
3.4.17.23 | angiotensin-converting enzyme 2 |
hepatic stellate cell |
- |
708195 |
3.4.21.6 | coagulation factor Xa |
hepatic stellate cell |
- |
753093 |
3.4.21.7 | plasmin |
hepatic stellate cell |
- |
718070 |
3.4.22.1 | cathepsin B |
hepatic stellate cell |
- |
708641 |
3.4.24.35 | gelatinase B |
hepatic stellate cell |
- |
696980 |
3.4.24.87 | ADAMTS13 endopeptidase |
hepatic stellate cell |
- |
670063, 679396, 719163 |
3.4.24.B10 | ADAM12 endopeptidase |
hepatic stellate cell |
- |
680191, 681003, 734657 |
3.6.1.5 | apyrase |
hepatic stellate cell |
- |
720442 |
6.2.1.3 | long-chain-fatty-acid-CoA ligase |
hepatic stellate cell |
- |
744397 |
2.7.1.137 | phosphatidylinositol 3-kinase |
hepatic stellate cell |
a primary cell type in the liver responsible for excess collagen deposition during fibrosis |
708644 |
3.4.24.87 | ADAMTS13 endopeptidase |
hepatic stellate cell |
ADAMTS13 is secreted by almost all tissues but primarily by hepatic stellate cells |
713347 |
3.4.24.B9 | ADAM9 endopeptidase |
hepatic stellate cell |
cells secrete a alternatively spliced variant of enzyme promoting carcinoma invasion |
668152 |
3.9.1.3 | phosphohistidine phosphatase |
hepatic stellate cell |
enzyme (PHP14) expression is upregulated in fibrotic liver and mainly in hepatic stellate cells |
757452 |
3.4.21.73 | u-Plasminogen activator |
hepatic stellate cell |
high enzyme level |
669677 |
2.4.2.28 | S-methyl-5'-thioadenosine phosphorylase |
hepatic stellate cell |
high expression in activated hepatic stellate cells |
737123 |
3.4.24.24 | gelatinase A |
hepatic stellate cell |
HSC-180 cell |
712625 |
2.3.1.26 | sterol O-acyltransferase |
hepatic stellate cell |
isozyme ACAT1 is the major isozyme in human primary hepatic stellate cells, little isozyme ACAT2 expression in the cells |
736580 |
3.4.22.1 | cathepsin B |
hepatic stellate cell |
negligible expression of cathepsin B in hepatic stellate cells |
-, 708641 |
3.4.22.62 | caspase-9 |
hepatic stellate cell |
primary cultures of, in vitro activation by atorvastatin, mevalonic acid and U0126, an activator of the extracellular signal-regulated protein kinase (ERK1/2) |
-, 699949 |
2.7.11.30 | receptor protein serine/threonine kinase |
hepatic stellate cell |
primary, differential TGF-beta-mediated activation of Smad2 and Smad3 in activated and non-activated cells, overview |
665481 |
1.1.1.300 | NADP-retinol dehydrogenase |
hepatic stellate cell |
quantitative PCR enzyme expression analysis |
761488 |
3.4.24.87 | ADAMTS13 endopeptidase |
hepatic stellate cell |
retinoid enriched, i.e. lipocyte, secretes the enzyme |
711809 |
3.4.24.87 | ADAMTS13 endopeptidase |
hepatic stellate cell |
the dramatically increased ADAMTS-13 protein and proteolytic activity in the activated hepatic stellate cells in vitro and in vivo may be important part of functions of activated hepatic stellate cells, perhaps by modulating the processes of liver regeneration or formation of liver fibrosis after various insults |
670063 |