EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.135 | GDP-6-deoxy-D-talose 4-dehydrogenase |
fibroblast |
cultured skin fibroblast |
654167 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
fibroblast |
isoform 11betaHSD1 |
741066 |
1.1.1.153 | sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) |
fibroblast |
amniotic, cell culture |
286016 |
1.1.1.153 | sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) |
fibroblast |
dermal, cell culture |
286017 |
1.1.1.178 | 3-hydroxy-2-methylbutyryl-CoA dehydrogenase |
fibroblast |
- |
286121, 286123, 697369, 711851 |
1.1.1.188 | prostaglandin-F synthase |
fibroblast |
- |
740414 |
1.1.1.21 | aldose reductase |
fibroblast |
- |
697266 |
1.1.1.211 | long-chain-3-hydroxyacyl-CoA dehydrogenase |
fibroblast |
- |
686162, 761165 |
1.1.1.211 | long-chain-3-hydroxyacyl-CoA dehydrogenase |
fibroblast |
skin fibroblast |
656815 |
1.1.1.22 | UDP-glucose 6-dehydrogenase |
fibroblast |
primary fivbroblast |
761985 |
1.1.1.31 | 3-hydroxyisobutyrate dehydrogenase |
fibroblast |
- |
670284 |
1.1.1.34 | hydroxymethylglutaryl-CoA reductase (NADPH) |
fibroblast |
- |
695855 |
1.1.1.37 | malate dehydrogenase |
fibroblast |
dermal, activity of MDH1 is reduced in old human dermal fibroblasts |
723540 |
1.1.1.49 | glucose-6-phosphate dehydrogenase (NADP+) |
fibroblast |
G6PD deficiency is associated with premature senescence of human fibroblasts |
689997 |
1.1.1.8 | glycerol-3-phosphate dehydrogenase (NAD+) |
fibroblast |
adipofibroblast, embryonic cell culture, up to 10fold increase of activity in presence of chicken serum, further increase in presence of embryonic chicken serum |
657144 |
1.1.1.95 | phosphoglycerate dehydrogenase |
fibroblast |
skin-derived |
698189 |
1.1.1.96 | diiodophenylpyruvate reductase |
fibroblast |
- |
287552 |
1.1.99.2 | L-2-hydroxyglutarate dehydrogenase |
fibroblast |
- |
699377 |
1.1.99.24 | hydroxyacid-oxoacid transhydrogenase |
fibroblast |
of healthy subjects and patients with D-2-hydroxyglutaric aciduria |
675230 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
fibroblast |
- |
674370 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
fibroblast |
mouse embryonic fibroblasts |
764701 |
1.11.1.6 | catalase |
fibroblast |
- |
677210 |
1.13.11.12 | linoleate 13S-lipoxygenase |
fibroblast |
- |
765470 |
1.13.11.31 | arachidonate 12-lipoxygenase |
fibroblast |
- |
765070, 765470 |
1.13.11.33 | arachidonate 15-lipoxygenase |
fibroblast |
- |
765470 |
1.13.11.33 | arachidonate 15-lipoxygenase |
fibroblast |
15-LOX-1 |
706877 |
1.13.11.33 | arachidonate 15-lipoxygenase |
fibroblast |
low expression |
706579 |
1.13.11.33 | arachidonate 15-lipoxygenase |
fibroblast |
rheumatoid arthritis tissue |
701978 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
fibroblast |
- |
395502, 711952, 713591 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
fibroblast |
diploid fibroblast cells FS-4 |
395503 |
1.14.11.2 | procollagen-proline 4-dioxygenase |
fibroblast |
- |
439213, 439242, 439243 |
1.14.11.2 | procollagen-proline 4-dioxygenase |
fibroblast |
adult and fetal skin, the type I enzyme is the main enzyme form |
439243 |
1.14.11.2 | procollagen-proline 4-dioxygenase |
fibroblast |
foreskin |
439247 |
1.14.11.2 | procollagen-proline 4-dioxygenase |
fibroblast |
gingival fibroblast |
684766 |
1.14.11.27 | [histone H3]-dimethyl-L-lysine36 demethylase |
fibroblast |
embryonic |
700374 |
1.14.11.27 | [histone H3]-dimethyl-L-lysine36 demethylase |
fibroblast |
MEF |
754726 |
1.14.11.30 | hypoxia-inducible factor-asparagine dioxygenase |
fibroblast |
embryonic fibriblast |
764438 |
1.14.11.4 | procollagen-lysine 5-dioxygenase |
fibroblast |
- |
-, 673470, 675763, 698942, 726309, 745323, 746479 |
1.14.11.4 | procollagen-lysine 5-dioxygenase |
fibroblast |
from fibrotic skin of patients with systemic sclerosis |
659266 |
1.14.11.4 | procollagen-lysine 5-dioxygenase |
fibroblast |
of skin, expression only of LH2long |
659845 |
1.14.11.4 | procollagen-lysine 5-dioxygenase |
fibroblast |
skin |
659652, 745334, 745445 |
1.14.11.4 | procollagen-lysine 5-dioxygenase |
fibroblast |
skin and embryonic |
-, 746171 |
1.14.11.4 | procollagen-lysine 5-dioxygenase |
fibroblast |
synovial osteoarthritic |
724702 |
1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
fibroblast |
- |
755188 |
1.14.11.65 | [histone H3]-dimethyl-L-lysine9 demethylase |
fibroblast |
primary |
701223 |
1.14.11.66 | [histone H3]-trimethyl-L-lysine9 demethylase |
fibroblast |
in wild-type fibroblasts, the chromatin of ribosomal genes, which is dense with H3K9 methylation, lacks JMJD2b-GFP-1086, while mutant and truncated forms of JMJD2b densely occupie the nucleolar compartment |
712775 |
1.14.11.67 | [histone H3]-trimethyl-L-lysine4 demethylase |
fibroblast |
- |
725484 |
1.14.11.67 | [histone H3]-trimethyl-L-lysine4 demethylase |
fibroblast |
embryonic |
685984 |
1.14.11.67 | [histone H3]-trimethyl-L-lysine4 demethylase |
fibroblast |
MEF |
754726 |
1.14.11.67 | [histone H3]-trimethyl-L-lysine4 demethylase |
fibroblast |
mouse embryonic fibroblasts, MEFs |
744866 |
1.14.11.68 | [histone H3]-trimethyl-L-lysine27 demethylase |
fibroblast |
- |
753462, 755060 |
1.14.11.68 | [histone H3]-trimethyl-L-lysine27 demethylase |
fibroblast |
UTX is enriched around the transcription start sites of many HOX genes in primary human fibroblasts |
754877 |
1.14.11.69 | [histone H3]-trimethyl-L-lysine36 demethylase |
fibroblast |
embryonic fibroblast |
755480 |
1.14.11.7 | procollagen-proline 3-dioxygenase |
fibroblast |
- |
672947, 698181 |
1.14.11.7 | procollagen-proline 3-dioxygenase |
fibroblast |
isozyme P3H1 |
697189 |
1.14.11.7 | procollagen-proline 3-dioxygenase |
fibroblast |
isozyme P3H2 |
697189 |
1.14.11.7 | procollagen-proline 3-dioxygenase |
fibroblast |
isozyme P3H3 |
697189 |
1.14.11.B19 | [histone H3]-trimethyl-L-lysine56 demethylase |
fibroblast |
embryonic fibroblast cell |
755194 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
fibroblast |
- |
687570 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
fibroblast |
dermal |
687555 |
1.14.16.4 | tryptophan 5-monooxygenase |
fibroblast |
dermal |
658187 |
1.14.18.9 | 4alpha-methylsterol monooxygenase |
fibroblast |
- |
728037 |
1.14.18.9 | 4alpha-methylsterol monooxygenase |
fibroblast |
inhibition of sterol C4methyl oxidase induces activation of the cell cycle |
727093 |
1.14.19.3 | acyl-CoA 6-desaturase |
fibroblast |
skin fibroblast |
438421 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
fibroblast |
- |
438393 |
1.14.99.66 | [histone H3]-N6,N6-dimethyl-L-lysine4 FAD-dependent demethylase |
fibroblast |
- |
755188 |
1.17.4.1 | ribonucleoside-diphosphate reductase |
fibroblast |
- |
437909 |
1.17.4.2 | ribonucleoside-triphosphate reductase (thioredoxin) |
fibroblast |
isozymes R2 and p53R2 |
715583 |
1.17.4.4 | vitamin-K-epoxide reductase (warfarin-sensitive) |
fibroblast |
dermal, low expression rate |
675907 |
1.2.1.104 | pyruvate dehydrogenase system |
fibroblast |
- |
662948, 699383 |
1.2.1.105 | 2-oxoglutarate dehydrogenase system |
fibroblast |
- |
654854, 671961 |
1.2.1.12 | glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) |
fibroblast |
in both fetal and senior cells, considerable GAPDH is present in intracellular domains characterized by significantly reduced catalysis. Human cells contain significant intracellular levels of enzymatically inactive GAPDH which is age-independent |
654849 |
1.2.1.31 | L-aminoadipate-semialdehyde dehydrogenase |
fibroblast |
- |
712017 |
1.2.1.48 | long-chain-aldehyde dehydrogenase |
fibroblast |
- |
656817, 725656 |
1.2.4.1 | pyruvate dehydrogenase (acetyl-transferring) |
fibroblast |
- |
710839 |
1.3.1.21 | 7-dehydrocholesterol reductase |
fibroblast |
- |
349276 |
1.3.1.21 | 7-dehydrocholesterol reductase |
fibroblast |
of healthy persons, heterozygous persons, and Smith-Lemli-Opitz syndrome patients |
656818 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
fibroblast |
- |
684907 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
fibroblast |
cultured |
396207 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
fibroblast |
cultured female and male genital skin fibroblasts |
396221 |
1.3.1.22 | 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+) |
fibroblast |
foreskin, Hs68 |
656656 |
1.3.1.24 | biliverdin reductase |
fibroblast |
- |
724924 |
1.3.1.6 | fumarate reductase (NADH) |
fibroblast |
- |
713389 |
1.3.1.70 | DELTA14-sterol reductase |
fibroblast |
of an 18-weeks-old fetus with autosomal recessive HEM/Greenberg skeletal dysplasia showing enzyme-deficiency |
654166 |
1.3.1.72 | DELTA24-sterol reductase |
fibroblast |
fibroblast from skin |
288497 |
1.3.3.4 | protoporphyrinogen oxidase |
fibroblast |
- |
390981 |
1.3.3.6 | acyl-CoA oxidase |
fibroblast |
- |
684293, 712822 |
1.3.8.1 | short-chain acyl-CoA dehydrogenase |
fibroblast |
- |
687031, 689021, 712126 |
1.3.8.4 | isovaleryl-CoA dehydrogenase |
fibroblast |
- |
391206, 391212, 391214, 699381 |
1.3.8.6 | glutaryl-CoA dehydrogenase (ETF) |
fibroblast |
- |
688177, 689338, 713046 |
1.3.8.6 | glutaryl-CoA dehydrogenase (ETF) |
fibroblast |
cultured |
391410 |
1.3.8.7 | medium-chain acyl-CoA dehydrogenase |
fibroblast |
- |
688185 |
1.3.8.8 | long-chain acyl-CoA dehydrogenase |
fibroblast |
- |
394665, 676027, 684281, 686160 |
1.3.8.8 | long-chain acyl-CoA dehydrogenase |
fibroblast |
normal and VLCAD-deficient individuals |
673935 |
1.3.99.23 | all-trans-retinol 13,14-reductase |
fibroblast |
- |
686872, 763769 |
1.3.99.5 | 3-oxo-5alpha-steroid 4-dehydrogenase (acceptor) |
fibroblast |
from all areas |
713519 |
1.4.3.13 | protein-lysine 6-oxidase |
fibroblast |
- |
391742, 685981, 687597, 687919, 696449 |
1.4.3.13 | protein-lysine 6-oxidase |
fibroblast |
secretion of free soluble enzyme |
659558 |
1.4.3.4 | monoamine oxidase |
fibroblast |
MAO A is prevalent in fibroblasts and placental tissue |
684241 |
1.4.3.4 | monoamine oxidase |
fibroblast |
of blood vessels |
655721 |