EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.11.1.7 | peroxidase |
eosinophil |
isolated from peritoneal lavage and gastric wall |
684225 |
1.11.2.2 | myeloperoxidase |
eosinophil |
- |
439734 |
1.13.11.12 | linoleate 13S-lipoxygenase |
eosinophil |
eosinophils are the major cell type expressing 12/15-LOX during the corneal wound healing process |
764651 |
1.13.11.31 | arachidonate 12-lipoxygenase |
eosinophil |
- |
742000, 765651 |
1.13.11.31 | arachidonate 12-lipoxygenase |
eosinophil |
eosinophils are the major cell type expressing 12/15-LOX during the corneal wound healing process |
764651 |
1.13.11.33 | arachidonate 15-lipoxygenase |
eosinophil |
- |
639237, 639243, 639247, 639248, 689807, 703628, 706579, 742000, 742613, 765651 |
1.13.11.33 | arachidonate 15-lipoxygenase |
eosinophil |
15-lipoxygenase activity is 100fold greater in eosinophils than in neutrophils |
639246 |
1.13.11.33 | arachidonate 15-lipoxygenase |
eosinophil |
15-LOX-1 |
706877 |
1.13.11.33 | arachidonate 15-lipoxygenase |
eosinophil |
eosinophil 15-lipoxygenase is a leukotriene A4 synthase |
639267 |
1.13.11.33 | arachidonate 15-lipoxygenase |
eosinophil |
eosinophils are the major cell type expressing 12/15-LOX during the corneal wound healing process |
764651 |
1.13.11.33 | arachidonate 15-lipoxygenase |
eosinophil |
high expression |
706579 |
1.13.11.33 | arachidonate 15-lipoxygenase |
eosinophil |
peak-I 15 lipoxygenase is the predominant enzyme form |
639240 |
1.13.11.34 | arachidonate 5-lipoxygenase |
eosinophil |
- |
704997, 711100, 742001 |
1.14.14.94 | leukotriene-B4 20-monooxygenase |
eosinophil |
- |
685340 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
eosinophil |
- |
742310 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
eosinophil |
inside-out patches from eosinophils activated with PMA |
671829 |
2.3.1.147 | glycerophospholipid arachidonoyl-transferase (CoA-independent) |
eosinophil |
- |
701639 |
2.3.1.37 | 5-aminolevulinate synthase |
eosinophil |
high expression of isoform ALAS1 |
703855 |
2.4.1.152 | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase |
eosinophil |
FT-IV mRNA is the predominant transcript in eosinophils isolated from human blood, TGF-beta1 upregulates FT-IV mRNA expression |
671207 |
2.4.1.152 | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase |
eosinophil |
FT-VII mRNA is weakly expressed in eosinophils isolated from human blood, its expression is up-regulated by TGF-beta1 to some extent |
671207 |
2.7.11.18 | myosin-light-chain kinase |
eosinophil |
- |
661920 |
3.1.1.5 | lysophospholipase |
eosinophil |
- |
680335 |
3.1.3.16 | protein-serine/threonine phosphatase |
eosinophil |
- |
692321 |
3.3.2.6 | leukotriene-A4 hydrolase |
eosinophil |
- |
708181 |
3.3.2.6 | leukotriene-A4 hydrolase |
eosinophil |
roughly two-thirds of the eosinophil population express 5-lipoxygenase (5-LO), and of those 5-LO-expressing cells, over 99% express both LTA4 hydrolase and LTC4 synthase. Peripheral blood eosinophils cultured in vitro produce LTB4 when unstimulated, and they release significantly elevated levels of LTB4 when stimulated with aspirin-lysine, PMA, and platelet-activating factor |
752450 |
3.3.2.6 | leukotriene-A4 hydrolase |
eosinophil |
used as control for the expression of 5-LO pathway enzymes |
679295 |
3.4.14.5 | dipeptidyl-peptidase IV |
eosinophil |
- |
699329 |
3.5.3.15 | protein-arginine deiminase |
eosinophil |
- |
711811 |
3.6.1.2 | trimetaphosphatase |
eosinophil |
- |
209941 |
4.4.1.20 | leukotriene-C4 synthase |
eosinophil |
- |
644485, 644486, 644488 |
4.4.1.20 | leukotriene-C4 synthase |
eosinophil |
co-localization for 5-lipoxygenase activating protein, LTC4 synthase, cyclooxygenase-1 and prostaglandin D2 synthase in nasal biopsies, 10% of LTC4 synthase-positive cells being eosinophils in perennial and seasonal allergic rhinitis biopsies. In the rhinitic biopsies, LTC4 synthase is detectable in 19% of eosinophils |
708181 |
5.2.1.8 | peptidylprolyl isomerase |
eosinophil |
primary |
705854 |
5.3.2.1 | phenylpyruvate tautomerase |
eosinophil |
- |
703331 |
5.3.3.12 | L-dopachrome isomerase |
eosinophil |
- |
703331, 727347 |