EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.188 | prostaglandin-F synthase |
endothelium |
- |
725083 |
1.1.1.188 | prostaglandin-F synthase |
endothelium |
isozyme PGF synthase I in endothelial cells of the whole area of the spinal cord, and isozyme PGF synthase II in endothelial cells of the blood vessels only |
655139 |
1.1.1.188 | prostaglandin-F synthase |
endothelium |
liver-type isozyme, sinusoidal endothelial cells in the liver |
654159 |
1.1.1.21 | aldose reductase |
endothelium |
aortic, higher activity in aged compared to young rats |
710793 |
1.13.11.31 | arachidonate 12-lipoxygenase |
endothelium |
pulmonary artery endothelial cell |
763866 |
1.13.11.33 | arachidonate 15-lipoxygenase |
endothelium |
- |
-, 742845 |
1.14.11.29 | hypoxia-inducible factor-proline dioxygenase |
endothelium |
- |
743284 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
endothelium |
- |
-, 440216, 440218, 440236, 440240, 660022, 674558, 687734, 765745 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
endothelium |
aorta, cell culture |
440204 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
endothelium |
comparison of endothelial and neuronal isoform |
658116 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
endothelium |
constitutive, from pulmonary artery |
440235 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
endothelium |
endothelial enzyme |
671728 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
endothelium |
eNOS, endothelial cells of blood vessels |
687358 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
endothelium |
isoform III |
440226, 440229 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
endothelium |
liver, lung, adrenal glandcolon, isoform II |
440226 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
endothelium |
lung, uterus, stomach |
440226 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
endothelium |
specific isozyme eNOS |
674451 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
endothelium |
umbilical vein cells |
440236 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
endothelium |
vascular, constitutive expression of the endothelial isozyme in endothelial cells |
673002 |
1.14.13.9 | kynurenine 3-monooxygenase |
endothelium |
vascular, of villous blood vessels |
660112 |
1.17.3.2 | xanthine oxidase |
endothelium |
- |
684783, 685983 |
1.2.1.25 | branched-chain alpha-keto acid dehydrogenase system |
endothelium |
- |
763513, 763515 |
1.21.99.3 | thyroxine 5-deiodinase |
endothelium |
of fetal vessels |
659569 |
1.3.1.72 | DELTA24-sterol reductase |
endothelium |
- |
744737 |
1.4.3.13 | protein-lysine 6-oxidase |
endothelium |
- |
391742, 685981 |
1.4.3.21 | primary-amine oxidase |
endothelium |
- |
712188 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
endothelium |
- |
688605, 710782, 711688 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
endothelium |
abdominal aortic endothelial cells |
686418 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
endothelium |
coronary artery endothelial cells |
687649 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
endothelium |
lung endothelial cell |
687587 |
1.6.5.2 | NAD(P)H dehydrogenase (quinone) |
endothelium |
pulmonary |
725060 |
1.6.5.2 | NAD(P)H dehydrogenase (quinone) |
endothelium |
pulmonary arterial endothelial cell. Increase in enzyme protein and activity upon hyperoxia, i.e. exposure to 95% O2 for 48 h |
671220 |
2.3.1.50 | serine C-palmitoyltransferase |
endothelium |
vascular |
487177 |
2.3.1.97 | glycylpeptide N-tetradecanoyltransferase |
endothelium |
lung, NMT1 |
706890 |
2.3.1.B41 | protein-long-chain fatty-acyl-lysine deacylase (NAD+) |
endothelium |
- |
756672 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
endothelium |
- |
487830 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
endothelium |
aortic cell suspension culture |
487840 |
2.4.1.152 | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase |
endothelium |
the enzyme is expressed in endothelial cells lining the high endothelial venules of perpheral lymph nodes, mesenteric lymph nodes and Peverยs patches |
639534 |
2.4.1.214 | glycoprotein 3-alpha-L-fucosyltransferase |
endothelium |
- |
662566 |
2.4.1.224 | glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase |
endothelium |
- |
736318 |
2.4.1.225 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase |
endothelium |
- |
736318 |
2.4.1.87 | N-acetyllactosaminide 3-alpha-galactosyltransferase |
endothelium |
primary and permanent, aortic |
489479 |
2.7.1.107 | diacylglycerol kinase (ATP) |
endothelium |
- |
640383 |
2.7.1.137 | phosphatidylinositol 3-kinase |
endothelium |
umbilical vein endothelial cells |
640927 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
endothelium |
PI3Kgamma |
672786 |
2.7.1.91 | sphingosine kinase |
endothelium |
- |
661509 |
2.7.10.1 | receptor protein-tyrosine kinase |
endothelium |
- |
490403, 490474, 490540, 694051 |
2.7.10.1 | receptor protein-tyrosine kinase |
endothelium |
endothelial cell surface receptor tyrosine kinase |
490391 |
2.7.10.1 | receptor protein-tyrosine kinase |
endothelium |
endothelial cells and their progenitors |
490536, 490537 |
2.7.10.1 | receptor protein-tyrosine kinase |
endothelium |
endothelium of blood vessel |
490572 |
2.7.10.1 | receptor protein-tyrosine kinase |
endothelium |
gene is expressed specifically in the endothelial lineage, present in endothelial cell precursors, angioblasts, and also in endothelial cells of sprouting blood vessels |
490541 |
2.7.10.1 | receptor protein-tyrosine kinase |
endothelium |
maternal decidual vascular endothelial cells |
490540 |
2.7.10.1 | receptor protein-tyrosine kinase |
endothelium |
selectively expressed in vascular endothelium |
490402 |
2.7.10.2 | non-specific protein-tyrosine kinase |
endothelium |
preferentially expressed in epithelial and endothelial cells |
490462 |
2.7.10.2 | non-specific protein-tyrosine kinase |
endothelium |
PYK2 |
673223 |
2.7.11.11 | cAMP-dependent protein kinase |
endothelium |
- |
694508, 738093 |
2.7.11.12 | cGMP-dependent protein kinase |
endothelium |
- |
693879 |
2.7.11.13 | protein kinase C |
endothelium |
aortic |
662054 |
2.7.11.18 | myosin-light-chain kinase |
endothelium |
- |
491283, 640646, 640663, 662316 |
2.7.11.18 | myosin-light-chain kinase |
endothelium |
endothelial isozyme EC MLCK |
662504 |
2.7.11.18 | myosin-light-chain kinase |
endothelium |
specific isozyme |
663442 |
2.7.11.24 | mitogen-activated protein kinase |
endothelium |
prostate endothelial cells |
665029 |
2.7.11.30 | receptor protein serine/threonine kinase |
endothelium |
embryonic cells |
666312 |
2.7.11.31 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase |
endothelium |
- |
644987 |
2.7.4.3 | adenylate kinase |
endothelium |
vascular endothelial cells |
674609 |
2.7.7.86 | cyclic GMP-AMP synthase |
endothelium |
primary human endothelial cells mount robust IFN-I responses to human Cytomegalovirus that are dependent upon cyclic GMP-AMP synthase cGAS, STING, and interferon regulatory factor IRF3 signaling |
738941 |
2.7.8.1 | ethanolaminephosphotransferase |
endothelium |
CEPT1 is elevated in diseased lower extremity arterial intima of individuals with peripheral arterial disease and diabetes |
760955 |
2.7.8.2 | diacylglycerol cholinephosphotransferase |
endothelium |
CEPT1 is elevated in diseased lower extremity arterial intima of individuals with peripheral arterial disease and diabetes |
760955 |
3.1.1.3 | triacylglycerol lipase |
endothelium |
- |
691320 |
3.1.1.32 | phospholipase A1 |
endothelium |
isozyme endothelial lipase |
678494 |
3.1.1.34 | lipoprotein lipase |
endothelium |
- |
693188, 751275 |
3.1.1.34 | lipoprotein lipase |
endothelium |
aortic endothelial cells |
665649 |
3.1.26.10 | ribonuclease IX |
endothelium |
immortalized umbilical vein endothelial cells EaHy 926 |
646297 |
3.1.3.2 | acid phosphatase |
endothelium |
- |
666100 |
3.1.3.4 | phosphatidate phosphatase |
endothelium |
specific expression of DPPL2, expression in endothelial cell lines, overview |
679998 |
3.1.3.48 | protein-tyrosine-phosphatase |
endothelium |
increased expression in umbilical vascular endothelial cells and microvascular endothelial cells upon exposure to phorbol 12-myristate 13-acetate |
666310 |
3.1.3.53 | [myosin-light-chain] phosphatase |
endothelium |
- |
715719 |
3.1.3.53 | [myosin-light-chain] phosphatase |
endothelium |
monlayers of pulmonary artery endothelial cells |
665653 |
3.1.3.67 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase |
endothelium |
- |
694494 |
3.1.4.12 | sphingomyelin phosphodiesterase |
endothelium |
- |
677875 |
3.1.4.39 | alkylglycerophosphoethanolamine phosphodiesterase |
endothelium |
- |
730301 |
3.2.1.166 | heparanase |
endothelium |
the enzyme penetrates the endothelial layer that lines blood vessels |
755125 |
3.2.1.35 | hyaluronoglucosaminidase |
endothelium |
cells form tubular structures after stimulation by angiogenic factors, e.g. the enzyme and the basic fibroblast growth factor bFGF, treatment leads to cell survival and prevents from apoptosis, respectively |
651538 |
3.3.2.10 | soluble epoxide hydrolase |
endothelium |
- |
732722 |
3.3.2.10 | soluble epoxide hydrolase |
endothelium |
vascular |
663275 |
3.4.14.5 | dipeptidyl-peptidase IV |
endothelium |
- |
651079 |
3.4.14.5 | dipeptidyl-peptidase IV |
endothelium |
glomerular endothelial cells |
649626 |
3.4.14.5 | dipeptidyl-peptidase IV |
endothelium |
of spleen, lung, brain and vessels supplying the liver |
679710 |
3.4.15.1 | peptidyl-dipeptidase A |
endothelium |
- |
709411, 81241 |
3.4.15.1 | peptidyl-dipeptidase A |
endothelium |
vascular |
81241 |
3.4.17.12 | carboxypeptidase M |
endothelium |
arterial endothelium |
683099 |
3.4.17.23 | angiotensin-converting enzyme 2 |
endothelium |
and vascular walls of coronary arteries |
708649 |
3.4.17.23 | angiotensin-converting enzyme 2 |
endothelium |
the enzyme is present in endothelia overlying neo-intima formation and atherosclerotic plaques, but not in endothelial layer overlying normal vessel wall |
681180 |
3.4.21.22 | coagulation factor IXa |
endothelium |
factor IXa binds specifically to the surface of endothelial cells |
95337 |
3.4.21.34 | plasma kallikrein |
endothelium |
prekallikrein expression |
653115 |
3.4.21.6 | coagulation factor Xa |
endothelium |
- |
731536 |
3.4.21.68 | t-Plasminogen activator |
endothelium |
- |
699868 |
3.4.21.68 | t-Plasminogen activator |
endothelium |
of veins and arteries |
29575 |
3.4.21.69 | Protein C (activated) |
endothelium |
- |
684102 |
3.4.22.15 | cathepsin L |
endothelium |
incubation of endothelial progenitor cells with high levels of glucose dose-dependently decreases cathepsin L activity and protein expression, while other proteases such as cathepsins D and O, and matrix metalloproteases MMP-2 and MMP-9, are not altered. Cathepsin L mRNA level is not affected |
699608 |