EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.13.11.52 | indoleamine 2,3-dioxygenase |
dendritic cell |
CD123+/CCR6+ dendritic cells do not constitutively express indoleamine 2,3-dioxygenase, and, even if they express the enzyme after interferon-gamma treatment, they possess only limited T-cell regulatory function |
395496 |
3.4.22.34 | Legumain |
dendritic cell |
resting and maturing |
650471 |
3.1.3.2 | acid phosphatase |
dendritic cell |
- |
652665, 679089 |
3.1.1.47 | 1-alkyl-2-acetylglycerophosphocholine esterase |
dendritic cell |
monocyte-derived cells show very low enzyme expression |
652685 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
dendritic cell |
- |
657703 |
2.4.3.9 | lactosylceramide alpha-2,3-sialyltransferase |
dendritic cell |
excessive GM3 is synthesized in atherosclerotic lesions by macrophages and dendritic cells directly within the arterial walls |
657703 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
dendritic cell |
the expression of the enzyme is selectively induced in specific splenic dendritic cell subsets when mice are exposed to the synthetic immunomodulatory reagent CTLA4-Ig |
659625 |
6.1.1.2 | tryptophan-tRNA ligase |
dendritic cell |
monocyte-derived mature |
661390 |
3.4.21.76 | Myeloblastin |
dendritic cell |
- |
664451 |
3.4.18.1 | cathepsin X |
dendritic cell |
- |
664854 |
3.4.14.1 | dipeptidyl-peptidase I |
dendritic cell |
cathepsin C activity in monocyte derived dendritic cells (ex vivo) decreases dramatically as they mature |
665144 |
3.1.1.77 | acyloxyacyl hydrolase |
dendritic cell |
XS52, an immature dendritic cell line derived from newborn BALB/c mouse epidermis and a bone marrow derived cell line |
665875 |
3.1.3.2 | acid phosphatase |
dendritic cell |
isozyme 5 a, secretion |
665956 |
3.2.1.14 | chitinase |
dendritic cell |
from spleen |
666758 |
1.1.1.205 | IMP dehydrogenase |
dendritic cell |
CD14+-derived dendritic cells |
668295 |
3.4.22.27 | cathepsin S |
dendritic cell |
- |
-, 667984, 668394, 668898, 669716, 679696, 696630, 696638, 696641, 696743, 698859, 699142, 699442, 701151, 701183, 753701 |
3.4.24.65 | macrophage elastase |
dendritic cell |
- |
668953 |
3.4.23.34 | cathepsin E |
dendritic cell |
myeloid dendritic cell |
669718 |
1.13.11.33 | arachidonate 15-lipoxygenase |
dendritic cell |
- |
672376, 701633 |
2.7.11.12 | cGMP-dependent protein kinase |
dendritic cell |
derived from CD14+ monocytes |
672779 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
dendritic cell |
tumor-associated dendritic cell, indoleamine 2,3-dioxygenase is up-regulated after maturation of dendritic cells in presence of prostaglandin E2 |
672782 |
1.14.14.94 | leukotriene-B4 20-monooxygenase |
dendritic cell |
bone marrow-derived, in vitro differentiation |
674761 |
2.7.1.137 | phosphatidylinositol 3-kinase |
dendritic cell |
the regulatory subunit p87PIKAP and the catalytic subunit p101 are both expressed |
674783 |
2.7.1.107 | diacylglycerol kinase (ATP) |
dendritic cell |
- |
675157 |
1.14.15.18 | calcidiol 1-monooxygenase |
dendritic cell |
- |
675686 |
2.7.11.10 | IkappaB kinase |
dendritic cell |
partly derived from bone marrow |
676147 |
3.4.23.34 | cathepsin E |
dendritic cell |
- |
677973, 677990, 679774, 681209, 696014, 709450 |
3.4.23.34 | cathepsin E |
dendritic cell |
mature form of CE in the endosomal structure |
678531 |
3.5.1.98 | histone deacetylase |
dendritic cell |
- |
678911 |
3.4.11.14 | cytosol alanyl aminopeptidase |
dendritic cell |
- |
681214 |
2.7.11.25 | mitogen-activated protein kinase kinase kinase |
dendritic cell |
ASK1 |
682954 |
3.4.21.20 | cathepsin G |
dendritic cell |
- |
683531, 691695 |
3.2.2.5 | NAD+ glycohydrolase |
dendritic cell |
- |
683740 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
dendritic cell |
expressed in antigen-presenting dendritic cells where tryptophan catabolism drives immune tolerance |
685950 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
dendritic cell |
monocyte-dervide dendritic cell |
686520 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
dendritic cell |
derived from bone marrow |
686721 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
dendritic cell |
bone marrow-derived |
687727 |
1.14.14.25 | cholesterol 24-hydroxylase |
dendritic cell |
- |
687987 |
3.6.5.2 | small monomeric GTPase |
dendritic cell |
prepared from tumor-bearing mice ex vivo. Tumor-induced dysregulation of endocytic activity of dendritic cells is mediated by reduced activity of several members of the small Rho GTPase family |
688152 |
2.4.1.102 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase |
dendritic cell |
maturation of dendritic cells leads to a rapid change in the expression of glycosyltransferases involved in O-linked glycosylation. A down-regulation of C2GnT1 mRNA and enzymatic activity is observed with a concurrent up-regulation of ST3Gal I and ST6GalNAc II mRNA resulting in a loss of the core 2 structures required for sLex expression as a P-selectin ligand |
688154 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
dendritic cell |
bone marrow-derived, mature and immature |
-, 688158 |
3.6.5.2 | small monomeric GTPase |
dendritic cell |
- |
688162, 698214, 735277 |
1.14.15.18 | calcidiol 1-monooxygenase |
dendritic cell |
monocyte-derived |
688675 |
2.7.11.24 | mitogen-activated protein kinase |
dendritic cell |
splenic |
690340 |
2.7.1.138 | ceramide kinase |
dendritic cell |
- |
691965 |
3.1.3.16 | protein-serine/threonine phosphatase |
dendritic cell |
- |
692321 |
5.3.99.3 | prostaglandin-E synthase |
dendritic cell |
follicular dendritic cell |
693452 |
3.4.17.12 | carboxypeptidase M |
dendritic cell |
- |
697395 |
3.4.22.36 | caspase-1 |
dendritic cell |
from peripheral blood |
698216 |
1.2.1.36 | retinal dehydrogenase |
dendritic cell |
- |
699331 |
2.7.1.127 | inositol-trisphosphate 3-kinase |
dendritic cell |
- |
699694 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
dendritic cell |
- |
673476, 700981, 711165, 711952, 712832, 712947, 713412 |
3.4.11.2 | membrane alanyl aminopeptidase |
dendritic cell |
- |
701354 |
5.3.99.2 | Prostaglandin-D synthase |
dendritic cell |
- |
701618 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
dendritic cell |
monocyte-derived, presence of large amounts of TG2 on cell surface |
703983 |
1.13.11.34 | arachidonate 5-lipoxygenase |
dendritic cell |
- |
704997, 711100, 743614 |
2.7.10.2 | non-specific protein-tyrosine kinase |
dendritic cell |
- |
705953, 723518 |
1.13.11.33 | arachidonate 15-lipoxygenase |
dendritic cell |
medium expression |
706579 |
3.4.24.23 | matrilysin |
dendritic cell |
antifibrotic pulmonary dendritic cell |
-, 707048 |
3.4.22.1 | cathepsin B |
dendritic cell |
myeloid and plasmacytoid dendritic cells differ in their cathepsin distribution, overview |
707640 |
3.4.22.1 | cathepsin B |
dendritic cell |
primary |
708694 |
3.4.24.80 | membrane-type matrix metalloproteinase-1 |
dendritic cell |
- |
709223 |
3.4.21.79 | granzyme B |
dendritic cell |
- |
709759 |
3.4.22.15 | cathepsin L |
dendritic cell |
- |
711708 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
dendritic cell |
mature, but not immature dendritic cells metabolize tryptophan |
711776 |
1.14.99.38 | cholesterol 25-monooxygenase |
dendritic cell |
- |
-, 715833 |
3.1.3.5 | 5'-nucleotidase |
dendritic cell |
CD73 |
716355 |
3.4.24.35 | gelatinase B |
dendritic cell |
primary |
717522 |
2.7.11.10 | IkappaB kinase |
dendritic cell |
- |
722119 |
1.4.3.2 | L-amino-acid oxidase |
dendritic cell |
- |
726320 |
5.3.3.12 | L-dopachrome isomerase |
dendritic cell |
- |
727347 |
3.1.1.77 | acyloxyacyl hydrolase |
dendritic cell |
colonic |
730832 |
3.4.22.59 | caspase-6 |
dendritic cell |
- |
731755 |
3.4.22.61 | caspase-8 |
dendritic cell |
- |
732273 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
dendritic cell |
- |
733904 |
1.13.11.31 | arachidonate 12-lipoxygenase |
dendritic cell |
immature |
742000 |
1.13.11.33 | arachidonate 15-lipoxygenase |
dendritic cell |
immature |
742000 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
dendritic cell |
- |
742310 |
1.13.11.31 | arachidonate 12-lipoxygenase |
dendritic cell |
bone marrow-derived |
-, 742978 |
1.2.1.36 | retinal dehydrogenase |
dendritic cell |
from gut-related lymphoid organs |
-, 743660 |
4.1.2.27 | sphinganine-1-phosphate aldolase |
dendritic cell |
- |
748338 |
7.2.2.10 | P-type Ca2+ transporter |
dendritic cell |
- |
750486 |
3.1.1.4 | phospholipase A2 |
dendritic cell |
secreted phospholipase A2-IID is preferentially and abundantly expressed in dendritic cells in lymphoid organs |
751474 |
3.4.22.27 | cathepsin S |
dendritic cell |
specific localization of cathepsin S activity in dendritic cells |
753968 |
3.4.11.3 | cystinyl aminopeptidase |
dendritic cell |
- |
754324, 754389 |
3.4.23.B24 | signal peptide peptidase |
dendritic cell |
- |
754400 |
3.4.24.B12 | ADAMTS5 endopeptidase |
dendritic cell |
- |
755055 |
2.7.1.67 | 1-phosphatidylinositol 4-kinase |
dendritic cell |
- |
760073 |
1.2.1.36 | retinal dehydrogenase |
dendritic cell |
isoform RALDH2 is dominantly expressed in dendritic cells |
763337 |