EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.141 | 15-hydroxyprostaglandin dehydrogenase (NAD+) |
corpus luteum |
- |
740130 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
corpus luteum |
at early and mid pregnancy up to 71 days, 3beta-hydroxysteroid dehydrogenase protein is observed in large luteal cells, while on day 71, the enzyme is present exclusively in small luteal cells. Enzyme mRNA is detected in all investigated samples isolated at different stages of pregnancy |
686588 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
corpus luteum |
enzyme expression during diestrus, overview |
670027 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
corpus luteum |
primary culture |
670036 |
1.1.1.145 | 3beta-hydroxy-DELTA5-steroid dehydrogenase |
corpus luteum |
weak expression of 3beta-hydroxysteroid dehydrogenase in newly formed corpora lutea, which gradually increases followed by decrease on day 20. In vascularised apical region of young corpora lutea, luteal cells with more intensive immunostaining predominate. Distribution of 3beta-hydroxysteroid dehydrogenase and androgen receptor differ within various generations of corpora lutea |
690002 |
1.1.1.146 | 11beta-hydroxysteroid dehydrogenase |
corpus luteum |
expression of mRNA for 11beta-hydroxysteroid dehydrogenase type 1, 11beta-hydroxysteroid dehydrogenase type 2 and for glucocorticoid receptor during the estrous cycle. Level of 11beta-hydroxysteroid dehydrogenase type 1 mRNA is higher at the regressed state than at the other stages, whereas level of 11beta-hydroxysteroid dehydrogenase type 2 mRNA is lower at the regressed stage than at the other stages |
694281 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
corpus luteum |
- |
737453, 741393 |
1.1.1.149 | 20alpha-hydroxysteroid dehydrogenase |
corpus luteum |
transcripts of galectin-3 are restricted to corpus luteum and always coincident to the expression of 20alpha-hydroxysteroid dehydrogenase. In the nonpregnant ovary, signals for both galectin-1 and -3 are intense in the old, regressing corpora lutea formed at previous estrous cycles. In the newly formed corpora lutea, the signal intensity of galectin-1 first increases at the starting point of regression followed by increasing galectin-3/20alpha-hydroxysteroid dehydrogenase expressions. Under gestation with active progesterone production, signals for both galectin-1 and -3 in corpora lutea completely disappear. At the perinatal stage, intense expressions of galectin-3/20alpha-hydroxysteroid dehydrogenase recover in the remaining corpora lutea of gestation with the temporal expression of galectin-1 and continue until weaning |
688136 |
1.1.1.188 | prostaglandin-F synthase |
corpus luteum |
at days 12-14 of pregnancy and the estrous cycle, the expression of prostaglandin E2 synthase, prostaglandin F synthase, and carbonyl reductase/prostaglandin 9-ketoreductase genes and prostaglandin E2 synthase/prostaglandin F synthase ratio are significantly higher in corpora lutea of the pregnant gilts compared to the corpora lutea from the parallel ovaries of the cyclic gilts. There is no difference in expression of prostaglandin E2 synthase, prostaglandin F synthase, and carbonyl reductase/prostaglandin 9-ketoreductase genes and prostaglandin E2 synthase/prostaglandin F synthase ratio between corpora lutea ipsi- and contralateral to the uterine horn with the developing embryos |
689092 |
1.1.1.188 | prostaglandin-F synthase |
corpus luteum |
high expression level of the lung-type and the microsomal endometrium-type isozymes |
661605 |
1.1.1.188 | prostaglandin-F synthase |
corpus luteum |
no or very low expression of prostaglandin F2alpha synthase synthase |
684436 |
1.1.1.189 | prostaglandin-E2 9-reductase |
corpus luteum |
- |
657211 |
1.1.1.189 | prostaglandin-E2 9-reductase |
corpus luteum |
at days 12-14 of pregnancy and the estrous cycle, the expression of prostaglandin E2 synthase, prostaglandin F synthase, and carbonyl reductase/prostaglandin 9-ketoreductase genes and prostaglandin E2 synthase/prostaglandin F synthase ratio are significantly higher in corpora lutea of the pregnant gilts compared to the corpora lutea from the parallel ovaries of the cyclic gilts. There is no difference in expression of prostaglandin E2 synthase, prostaglandin F synthase, and carbonyl reductase/prostaglandin 9-ketoreductase genes and prostaglandin E2 synthase/prostaglandin F synthase ratio between corpora lutea ipsi- and contralateral to the uterine horn with the developing embryos |
689092 |
1.1.1.189 | prostaglandin-E2 9-reductase |
corpus luteum |
detection of immunosignals in all luteal cells. Enzymic activity is higher in late corpus luteum. Results support the idea that cyclooxygenase, nitric oxide synthase, and prostaglandin E2 9-ketoreductase regulate buffalo corpus luteum life span |
725914 |
1.1.1.189 | prostaglandin-E2 9-reductase |
corpus luteum |
expression of CBR1 mRNA and protein is constant during the cycle and pregnancy |
701271 |
1.1.1.189 | prostaglandin-E2 9-reductase |
corpus luteum |
pseudopregnant rabbits |
389468 |
1.1.1.210 | 3beta(or 20alpha)-hydroxysteroid dehydrogenase |
corpus luteum |
enzyme activity during stages of pseudo-pregnancy, 20alpha-hydroxysteroid dehydrogenase activity increases from day 1 to day 12, overview |
657329 |
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
corpus luteum |
- |
287209 |
1.1.1.270 | 3beta-hydroxysteroid 3-dehydrogenase |
corpus luteum |
cell culture |
762607 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
corpus luteum |
- |
677079 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
corpus luteum |
- |
670031, 675190 |
1.1.1.62 | 17beta-estradiol 17-dehydrogenase |
corpus luteum |
detectable throughout the luteal phase of the ovarian cycle and during pregnancy |
654934 |
1.1.1.B40 | 11beta-hydroxysteroid dehydrogenase (NAD+) |
corpus luteum |
expression of mRNA for 11beta-hydroxysteroid dehydrogenase type 1, 11beta-hydroxysteroid dehydrogenase type 2 and for glucocorticoid receptor during the estrous cycle. Level of 11beta-hydroxysteroid dehydrogenase type 1 mRNA is higher at the regressed state than at the other stages, whereas level of 11beta-hydroxysteroid dehydrogenase type 2 mRNA is lower at the regressed stage than at the other stages |
694281 |
1.14.11.67 | [histone H3]-trimethyl-L-lysine4 demethylase |
corpus luteum |
- |
690008 |
1.14.11.67 | [histone H3]-trimethyl-L-lysine4 demethylase |
corpus luteum |
histone H3-K4 demethylase is restricted to the corpus luteum |
690008 |
1.14.15.6 | cholesterol monooxygenase (side-chain-cleaving) |
corpus luteum |
- |
285423 |
1.14.15.6 | cholesterol monooxygenase (side-chain-cleaving) |
corpus luteum |
primary, from corpora lutea at day 6 to 10 of the estrous cycle, semi-quatitative enzyme expression analysis |
676926 |
1.14.15.6 | cholesterol monooxygenase (side-chain-cleaving) |
corpus luteum |
specific expressionin luteal cells, no expression in endothelial cells lining the blood vessels |
688147 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
corpus luteum |
PTGS1 enzyme activity is higher in late corpora lutea and lower in regressive ones |
727567 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
corpus luteum |
PTGS2 increases from early to late corpora lutea and lowers in regressive ones |
727567 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
corpus luteum |
significant increase in mRNA for PGHS-2 after treatment with prostaglandin F2alpha. PGHS-1 mRNA content remains unchanged |
658374 |
1.18.1.6 | adrenodoxin-NADP+ reductase |
corpus luteum |
- |
719386 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
corpus luteum |
- |
758875 |
2.7.1.137 | phosphatidylinositol 3-kinase |
corpus luteum |
- |
640875 |
2.7.11.25 | mitogen-activated protein kinase kinase kinase |
corpus luteum |
highest expression. In pigs, isoform MAP3K8 expression is higher in mature corpus luteums (or those of the mid-luteal phase) than in regressing corpus luteums (late luteal phase) |
762367 |
2.7.7.1 | nicotinamide-nucleotide adenylyltransferase |
corpus luteum |
activity is high during mid luteal phase, when corpora lutea are mature with respect to structure and function, while it dramatically decreases following PGF2alpha analog injection |
661539 |
3.1.1.13 | sterol esterase |
corpus luteum |
- |
133848, 133851, 133853 |
3.1.2.20 | acyl-CoA hydrolase |
corpus luteum |
MTE-II is strongly upregulated in corpus luteum during pregnancy |
666795 |
3.1.3.5 | 5'-nucleotidase |
corpus luteum |
- |
707006 |
3.1.6.2 | steryl-sulfatase |
corpus luteum |
weak immunostaining of STS irrespective of the oestrus cycle stage |
751416 |
3.1.6.8 | cerebroside-sulfatase |
corpus luteum |
- |
692081 |
3.4.21.26 | prolyl oligopeptidase |
corpus luteum |
- |
754790 |
3.4.22.55 | caspase-2 |
corpus luteum |
at estrus, activity is 7.6fold greater in the old corpus luteum compared to new corpus luteum |
666898 |
3.4.22.55 | caspase-2 |
corpus luteum |
immunostaining for caspase-2 increases as the luteal phase progresses |
666898 |
3.4.22.62 | caspase-9 |
corpus luteum |
activity increases transiently at mid-late luteal phase |
665826 |
3.4.22.62 | caspase-9 |
corpus luteum |
caspase-9 activity increases in the old corpus luteum at estrus, during the functional luteolysis |
666898 |
3.4.24.62 | magnolysin |
corpus luteum |
- |
31370, 31375, 31376, 668826 |
3.4.24.62 | magnolysin |
corpus luteum |
day 7-8 after heat period |
31372 |
5.3.99.3 | prostaglandin-E synthase |
corpus luteum |
- |
692088 |
5.3.99.3 | prostaglandin-E synthase |
corpus luteum |
from women undergoing treatment for infertility, expression of mPGES-2, mPGES-1, and cPGES |
668886 |
5.3.99.3 | prostaglandin-E synthase |
corpus luteum |
highest abundance of the protein |
661605 |
5.3.99.3 | prostaglandin-E synthase |
corpus luteum |
mPEGS-2 |
667830 |
5.3.99.4 | prostaglandin-I synthase |
corpus luteum |
widely distributed among different cell types, specific binding sites which may mediate luteotropic actions of the enzyme are only present in small and large luteal cells |
37482 |