EC Number   |
Recommended Name |
Source Tissue |
Reference |
|---|
   1.1.1.153 | sepiapterin reductase (L-erythro-7,8-dihydrobiopterin forming) |
brain stem |
monoaminergic field, neurons |
655138 |
 1.13.11.34 | arachidonate 5-lipoxygenase |
brain stem |
- |
439477 |
| 1.13.11.52 | indoleamine 2,3-dioxygenase |
brain stem |
- |
700466 |
| 1.14.13.39 | nitric-oxide synthase (NADPH) |
brain stem |
- |
-, 764938, 765779 |
| 1.14.13.39 | nitric-oxide synthase (NADPH) |
brain stem |
cerebrum shows higher activity than cerebellum |
-, 440203 |
| 1.14.14.19 | steroid 17alpha-monooxygenase |
brain stem |
- |
727367 |
| 1.14.15.4 | steroid 11beta-monooxygenase |
brain stem |
- |
688009 |
| 1.14.16.4 | tryptophan 5-monooxygenase |
brain stem |
- |
684813 |
| 1.14.16.4 | tryptophan 5-monooxygenase |
brain stem |
expression analysis |
689088 |
| 1.14.16.4 | tryptophan 5-monooxygenase |
brain stem |
expression of the native truncated mutant TPH2 |
689089 |
| 1.14.16.4 | tryptophan 5-monooxygenase |
brain stem |
raphe nuclei |
684737 |
| 1.14.16.4 | tryptophan 5-monooxygenase |
brain stem |
TPH2 mRNA expression in the midbrain part of the dorsal raphe nucleus and in the brainstem containing the rest of the raphe complex |
689230 |
| 1.14.17.1 | dopamine beta-monooxygenase |
brain stem |
- |
727633 |
| 1.14.17.3 | peptidylglycine monooxygenase |
brain stem |
- |
698532 |
| 1.14.99.1 | prostaglandin-endoperoxide synthase |
brain stem |
- |
673515, 686417 |
| 1.14.99.1 | prostaglandin-endoperoxide synthase |
brain stem |
PGHS-2 has lowest abundance in brain stem and pituitary gland |
698086 |
| 1.14.99.1 | prostaglandin-endoperoxide synthase |
brain stem |
PGSHS-1 has lowest abundance in brain stem and pituitary gland |
698086 |
| 1.2.1.105 | 2-oxoglutarate dehydrogenase system |
brain stem |
- |
762740 |
| 1.2.3.1 | aldehyde oxidase |
brain stem |
high expression |
390422 |
| 1.3.3.6 | acyl-CoA oxidase |
brain stem |
- |
712822 |
| 1.3.5.2 | dihydroorotate dehydrogenase (quinone) |
brain stem |
very low enzyme level |
713150 |
| 1.3.5.2 | dihydroorotate dehydrogenase (quinone) |
brain stem |
very low level both of expression and activity |
713150 |
| 1.4.3.1 | D-aspartate oxidase |
brain stem |
- |
712818 |
| 1.8.3.2 | thiol oxidase |
brain stem |
- |
659578, 659912, 669636 |
| 2.1.1.28 | phenylethanolamine N-methyltransferase |
brain stem |
- |
639450 |
| 2.3.1.23 | 1-acylglycerophosphocholine O-acyltransferase |
brain stem |
- |
755989 |
| 2.3.1.6 | choline O-acetyltransferase |
brain stem |
pChAT+ nerve fibers are found exclusively in the trigeminal and solitary systems. The ventral portion of the principal sensory nucleus contains many pChAT+ fibers |
687989 |
| 2.4.1.23 | sphingosine beta-galactosyltransferase |
brain stem |
highest activity together with spinal cord |
488992 |
| 2.4.1.47 | N-acylsphingosine galactosyltransferase |
brain stem |
cerebrum, cerebellum and brain stem of 14 and 21 days old rats |
489223 |
| 2.6.1.42 | branched-chain-amino-acid transaminase |
brain stem |
- |
675509 |
| 2.7.1.1 | hexokinase |
brain stem |
the contribution of glucokinase to total glucose-phosphorylating activity is of 12.4% in the brainstem |
705268 |
| 2.7.1.127 | inositol-trisphosphate 3-kinase |
brain stem |
- |
640746 |
| 2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
brain stem |
- |
708686 |
| 2.7.1.20 | adenosine kinase |
brain stem |
low expression level |
661642 |
| 2.7.1.91 | sphingosine kinase |
brain stem |
- |
675516 |
| 2.7.11.17 | Ca2+/calmodulin-dependent protein kinase |
brain stem |
alpha and beta isozymes |
664278 |
| 2.7.11.22 | cyclin-dependent kinase |
brain stem |
- |
662124 |
| 2.7.11.26 | tau-protein kinase |
brain stem |
- |
662124, 704555 |
| 2.7.9.3 | selenide, water dikinase |
brain stem |
- |
762075 |
| 3.1.3.41 | 4-nitrophenylphosphatase |
brain stem |
- |
664474 |
| 3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
brain stem |
- |
670448 |
| 3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
brain stem |
- |
691716 |
| 3.3.2.10 | soluble epoxide hydrolase |
brain stem |
- |
661683 |
| 3.4.17.23 | angiotensin-converting enzyme 2 |
brain stem |
- |
679707 |
| 3.4.17.23 | angiotensin-converting enzyme 2 |
brain stem |
about 20% of the ACE2 gene expression in kidney cortex |
668896 |
| 3.4.18.1 | cathepsin X |
brain stem |
- |
683448 |
| 3.4.21.34 | plasma kallikrein |
brain stem |
prekallikrein expression |
653115 |
| 3.4.22.27 | cathepsin S |
brain stem |
- |
697041 |
| 3.4.23.46 | memapsin 2 |
brain stem |
- |
713117 |
| 3.4.24.56 | insulysin |
brain stem |
- |
683700 |
| 3.4.24.61 | nardilysin |
brain stem |
nuclei, neuronal cells |
683930 |
| 3.4.24.B14 | neprilysin-2 |
brain stem |
high enzyme level |
733906 |
| 3.5.3.15 | protein-arginine deiminase |
brain stem |
- |
695453 |
| 4.1.1.15 | glutamate decarboxylase |
brain stem |
- |
700472 |
| 4.1.1.28 | aromatic-L-amino-acid decarboxylase |
brain stem |
both the neuronal and the extraneuronal AADC mRNA isoforms are present at early brain developmental stages in the brain stem |
702968 |
| 4.3.2.1 | argininosuccinate lyase |
brain stem |
- |
708319 |
| 4.3.2.1 | argininosuccinate lyase |
brain stem |
low mRNA content |
709968 |
| 4.6.1.1 | adenylate cyclase |
brain stem |
- |
691561 |
| 6.1.1.12 | aspartate-tRNA ligase |
brain stem |
- |
676127 |
| 6.1.1.23 | aspartate-tRNAAsn ligase |
brain stem |
- |
693741 |
| 6.3.2.2 | glutamate-cysteine ligase |
brain stem |
- |
672367 |
| 6.3.2.41 | N-acetylaspartylglutamate synthase |
brain stem |
- |
725423 |
| 6.3.2.42 | N-acetylaspartylglutamylglutamate synthase |
brain stem |
- |
725423 |
| 7.1.1.2 | NADH:ubiquinone reductase (H+-translocating) |
brain stem |
in the low positive schizophrenic group, a region of negative correlation between cerebral glucose metabolism and complex I activity is identified bilaterally in the cerebellum and brainstem |
694936 |
