EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.205 | IMP dehydrogenase |
blood plasma |
- |
736152 |
1.1.1.21 | aldose reductase |
blood plasma |
- |
738005 |
1.1.99.1 | choline dehydrogenase |
blood plasma |
choline and betaine levels |
688563 |
1.11.1.9 | glutathione peroxidase |
blood plasma |
- |
696581, 700167 |
1.11.2.2 | myeloperoxidase |
blood plasma |
- |
712327, 764087, 764466 |
1.13.11.19 | cysteamine dioxygenase |
blood plasma |
Cysteamine levels in plasma of rats fed the cysteamine supplemented diet are significantly higher than those in tissues of rats fed basal diet. Rats fed the cysteamine-supplemented diet have no markedly elevated levels of hypotaurine in plasma. |
671185 |
1.13.11.34 | arachidonate 5-lipoxygenase |
blood plasma |
- |
711711 |
1.13.11.52 | indoleamine 2,3-dioxygenase |
blood plasma |
- |
712647 |
1.13.99.1 | inositol oxygenase |
blood plasma |
from mice with acute kidney injury, MIOX expression is undetectable in healthy mice plasma |
-, 744739 |
1.13.99.1 | inositol oxygenase |
blood plasma |
plasma MIOX is increased in critically ill patients with acute kidney injury compared with patients without acute kidney injury and is highest in patients with oliguric acute kidney injury |
744739 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
blood plasma |
- |
701194 |
1.14.14.18 | heme oxygenase (biliverdin-producing) |
blood plasma |
- |
735090 |
1.14.14.55 | quinine 3-monooxygenase |
blood plasma |
- |
744743 |
1.14.16.4 | tryptophan 5-monooxygenase |
blood plasma |
- |
744508 |
1.14.17.1 | dopamine beta-monooxygenase |
blood plasma |
- |
660336, 686516 |
1.14.17.1 | dopamine beta-monooxygenase |
blood plasma |
a functional -1021C3T polymorphism in the DBH gene regulates plasma DBH activity, and individuals with the genotype T/T have genetically determined low DBH activity in their plasma |
703268 |
1.14.17.1 | dopamine beta-monooxygenase |
blood plasma |
dopamine beta-hydroxyase is reduced in rats subjected to chronic mild stress for 5 weeks. Imipramine treatment minimizes these chronic mild stress-induced reductions |
675798 |
1.14.19.1 | stearoyl-CoA 9-desaturase |
blood plasma |
- |
696683 |
1.14.19.30 | acyl-lipid (8-3)-desaturase |
blood plasma |
- |
734621, 734622, 746199 |
1.16.3.1 | ferroxidase |
blood plasma |
- |
-, 696112, 763223 |
1.17.3.2 | xanthine oxidase |
blood plasma |
- |
744744 |
1.17.3.2 | xanthine oxidase |
blood plasma |
enzyme activity in plasma of northern elephant seals during prolonged fasting and rest and voluntary associated apneas |
744744 |
1.17.3.2 | xanthine oxidase |
blood plasma |
low activity |
744744 |
1.4.3.21 | primary-amine oxidase |
blood plasma |
- |
391908, 391914, 391915, 391916, 391932, 686264, 686850, 687449, 688482, 688483, 724322 |
1.4.3.21 | primary-amine oxidase |
blood plasma |
semicarbazide-sensitive amine oxidase overexpression in cerebrovascular tissue of patients with Alzheimers disease cerebral amyloid angiopathy correlates with high SSAO activity in plasma of severe Alzheimers disease patients |
688490 |
1.4.3.22 | diamine oxidase |
blood plasma |
- |
391923 |
1.4.3.22 | diamine oxidase |
blood plasma |
amitriptyline at 0.03, 0.05, 0.1 and 0.5 mM concentrations lower enzyme activity in the plasma of the heparinised rat by 14, 22, 23 and 28%, respectively |
686558 |
1.4.3.22 | diamine oxidase |
blood plasma |
determination of fresh plasma diamine oxidase activity may serve as an effective tool to diagnose Cu deficiency in the bovine |
687323 |
1.4.3.22 | diamine oxidase |
blood plasma |
in vitro treatment with 100 nM, 0.05, 0.1 and 0.5 mM amitriptyline increases the guinea pig plasma diamine oxidase activity by 5, 7, 17 and 11%, respectively |
686558 |
1.4.3.22 | diamine oxidase |
blood plasma |
mean/median concentrations are between 0.5 and 1.5 ng/ml in healthy volunteers (n=58) and mastocytosis patients (n=19) and plateau at approximately 145 ng/ml during pregnancy |
764513 |
1.4.3.3 | D-amino-acid oxidase |
blood plasma |
- |
743131 |
1.5.1.20 | methylenetetrahydrofolate reductase [NAD(P)H] |
blood plasma |
- |
705297 |
1.6.3.5 | renalase |
blood plasma |
- |
741775, 742454 |
1.8.1.9 | thioredoxin-disulfide reductase |
blood plasma |
- |
742848 |
1.8.3.1 | sulfite oxidase |
blood plasma |
- |
691671 |
1.8.3.5 | prenylcysteine oxidase |
blood plasma |
VLDL contains a greater protein content of PCL1 than LDL or HDL |
706670 |
2.1.1.1 | nicotinamide N-methyltransferase |
blood plasma |
- |
690123 |
2.1.1.13 | methionine synthase |
blood plasma |
- |
705297 |
2.1.1.17 | phosphatidylethanolamine N-methyltransferase |
blood plasma |
- |
672830, 720359 |
2.1.1.2 | guanidinoacetate N-methyltransferase |
blood plasma |
- |
705297 |
2.1.1.2 | guanidinoacetate N-methyltransferase |
blood plasma |
L197P mutation in exon 6: guanidinoacetate increases to 33.6 microMol/l, creatine decreases to 24 microMol/l |
676024 |
2.1.1.5 | betaine-homocysteine S-methyltransferase |
blood plasma |
- |
705297 |
2.1.4.1 | glycine amidinotransferase |
blood plasma |
- |
673131, 705297 |
2.3.1.20 | diacylglycerol O-acyltransferase |
blood plasma |
- |
757321 |
2.3.1.43 | phosphatidylcholine-sterol O-acyltransferase |
blood plasma |
- |
685088, 686314, 686317, 686547, 686933, 687969, 688067, 702260, 702466, 703245, 703246, 703346, 703664, 703789, 705467, 705507, 705896, 706707, 718994, 720368, 737191, 756305, 756667, 757166, 757930 |
2.3.1.43 | phosphatidylcholine-sterol O-acyltransferase |
blood plasma |
about 75% of plasma LCAT is associated with HDL |
703346 |
2.3.1.43 | phosphatidylcholine-sterol O-acyltransferase |
blood plasma |
activity of LCAT in men with cardiovascular disease, CVD, compared to healthy men, overview. Plasma LCAT activity is 5% higher in CVD cases in association with higher total cholesterol, non-HDL cholesterol and triglycerides, ge-adjusted incident CVD is increased with higher LCAT activity, overview |
701993 |
2.3.1.43 | phosphatidylcholine-sterol O-acyltransferase |
blood plasma |
LCAT levels are higher in females compared to males |
705010 |
2.3.1.43 | phosphatidylcholine-sterol O-acyltransferase |
blood plasma |
the enzyme circulates in plasma, predominantly in association with high-density lipoproteins |
735428 |
2.3.1.6 | choline O-acetyltransferase |
blood plasma |
- |
737113 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
blood plasma |
- |
487858 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
blood plasma |
coagulation factor XIIIa |
487833 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
blood plasma |
identical with enzyme from placenta or platelets |
487820 |
2.3.2.2 | gamma-glutamyltransferase |
blood plasma |
- |
737142 |
2.3.2.2 | gamma-glutamyltransferase |
blood plasma |
elevated GGT in diabetic children could be due to release from apoptotic cells |
686578 |
2.3.2.2 | gamma-glutamyltransferase |
blood plasma |
four GGT fractions of different molecular weight are detected in all subjects of both genders: b-GGT, m-GGT, s-GGT (likely lipoprotein-bound, molecular masses >2000, 940, and 140 kDa, respectively), and a free fraction (f-GGT, 70 kDa). Higher total GGT activity in males is related mainly to f-GGT |
684407 |
2.3.2.2 | gamma-glutamyltransferase |
blood plasma |
plasma layer stratification might occur in primary lithium-heparin tubes for a limited number of routine clinical chemistry tests, introducing a statistically significant bias in the measurement of gamma-glutamyltransferase, lactate dehydrogenase, triglycerides and C-reactive protein in the upper vs. the bottom section. When delayed testing is necessary for these parameters, plasma should be separated after centrifugation and appropriately mixed before delayed/repeated analysis or aliquoting |
686156 |
2.4.1.152 | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase |
blood plasma |
- |
639518 |
2.4.1.152 | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase |
blood plasma |
enzyme activity is significantly higher in patients with chronic liver diseases than in that of normal controls |
639526 |
2.4.1.152 | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase |
blood plasma |
in individuals with plasma fucosyltransferase deficiency from Indonesia, either a missense mutation, G739A, in the catalytic domain, or a nonsense mutation, C945A, truncating the COOH terminus of the enzyme, leads to the total loss of the enzymatic activity of FUT6. 9% of individuals on the island of Java lack the plasma type enzyme. Activity is elevated in patients with a variety of malignant disorders, including liver cancer, elevated in heavy alcohol drinkers. Reduction of enzyme level in patients with schizophrenia |
639521 |
2.4.1.152 | 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase |
blood plasma |
the plasma enzyme appears at the last trimester of gestation |
639532 |
2.4.1.165 | N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase |
blood plasma |
group O |
488678 |
2.4.1.344 | type 2 galactoside alpha-(1,2)-fucosyltransferase |
blood plasma |
- |
740517 |
2.4.1.37 | fucosylgalactoside 3-alpha-galactosyltransferase |
blood plasma |
- |
489126, 489129 |
2.4.1.40 | glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase |
blood plasma |
- |
489126 |
2.4.1.40 | glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase |
blood plasma |
A |
489162, 489163 |
2.4.1.40 | glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase |
blood plasma |
blood group A1 |
489164 |
2.4.1.40 | glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase |
blood plasma |
blood group A1 and A2 |
489126 |
2.4.1.68 | glycoprotein 6-alpha-L-fucosyltransferase |
blood plasma |
- |
699825 |
2.4.1.69 | type 1 galactoside alpha-(1,2)-fucosyltransferase |
blood plasma |
- |
740517 |
2.4.2.1 | purine-nucleoside phosphorylase |
blood plasma |
- |
735978, 736556 |
2.4.2.26 | protein xylosyltransferase |
blood plasma |
- |
703904 |
2.4.2.26 | protein xylosyltransferase |
blood plasma |
XylT levels in plasma are approximately 200% lower than those in serum due in part to XylT released by platelets during blood clotting in vitro. In Xylt2+/+ mice, total serum XylT activity is 42% higher than in plasma. In Xylt2-/- mice, no significant difference between serum and plasma total XylT activity |
703904 |
2.4.2.4 | thymidine phosphorylase |
blood plasma |
- |
685912 |
2.4.2.8 | hypoxanthine phosphoribosyltransferase |
blood plasma |
- |
759254 |
2.4.3.1 | beta-galactoside alpha-(2,6)-sialyltransferase |
blood plasma |
- |
-, 701687, 703898 |
2.5.1.6 | methionine adenosyltransferase |
blood plasma |
- |
705297 |
2.6.1.1 | aspartate transaminase |
blood plasma |
- |
703947 |
2.6.1.2 | alanine transaminase |
blood plasma |
- |
760225 |
2.6.1.7 | kynurenine-oxoglutarate transaminase |
blood plasma |
- |
703233 |
2.6.1.7 | kynurenine-oxoglutarate transaminase |
blood plasma |
KAT I activity is significantly lower in plasma of patients with Parkinson's disease when compared with normal individuals |
675532 |
2.6.1.7 | kynurenine-oxoglutarate transaminase |
blood plasma |
KAT II activity is significantly lower in plasma of patients with Parkinson's disease when compared with normal individuals |
675532 |
2.7.1.165 | glycerate 2-kinase |
blood plasma |
- |
722379 |
2.7.1.171 | protein-fructosamine 3-kinase |
blood plasma |
- |
707456 |
2.7.1.21 | thymidine kinase |
blood plasma |
- |
758984 |
2.7.1.22 | ribosylnicotinamide kinase |
blood plasma |
- |
738213 |
2.7.1.30 | glycerol kinase |
blood plasma |
Aqp7-/- knockout mice have significantly lower plasma glycerol level under 12 h fasting conditions. |
682503 |
2.7.1.40 | pyruvate kinase |
blood plasma |
- |
661215 |
2.7.3.2 | creatine kinase |
blood plasma |
- |
642381 |
2.7.3.2 | creatine kinase |
blood plasma |
creatine kinase activity is much greater females than in males. Plasma creatine kinase activity may reflect the protein turnover, which is closely related to muscle growth rate |
687322 |
2.7.3.2 | creatine kinase |
blood plasma |
the inter-individual variation in creatine kinase activity in the general population is wide, ranging from below 25 to up to 5000 IU/L5, with particularly high levels in men and in persons of African ancestry |
739653 |
2.7.8.27 | sphingomyelin synthase |
blood plasma |
- |
707306, 738955, 760476 |
2.8.2.15 | steroid sulfotransferase |
blood plasma |
- |
661953 |
2.8.2.4 | estrone sulfotransferase |
blood plasma |
- |
739665 |
3.1.1.1 | carboxylesterase |
blood plasma |
- |
710690, 751792 |
3.1.1.2 | arylesterase |
blood plasma |
- |
665028, 678376, 678464, 681730, 691230, 691855, 693321, 693517, 695193, 714002, 714637 |
3.1.1.25 | 1,4-lactonase |
blood plasma |
- |
691230, 94285, 94286 |
3.1.1.3 | triacylglycerol lipase |
blood plasma |
- |
693511, 694786 |
3.1.1.3 | triacylglycerol lipase |
blood plasma |
post-heparin |
80840 |
3.1.1.3 | triacylglycerol lipase |
blood plasma |
post-heparin plasma |
665123 |