EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.239 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) |
Sertoli cell |
in contrast to the normal adult testis, the pediatric cryptorchid testis shows AKR1C3 expression in 18%-26% of Sertoli cells in patients at Tanner stages 2 and beyond |
713574 |
1.1.1.300 | NADP-retinol dehydrogenase |
Sertoli cell |
- |
761195 |
1.1.1.51 | 3(or 17)beta-hydroxysteroid dehydrogenase |
Sertoli cell |
- |
761195 |
1.1.1.95 | phosphoglycerate dehydrogenase |
Sertoli cell |
- |
654940 |
1.11.1.6 | catalase |
Sertoli cell |
- |
686055, 701310 |
1.13.11.71 | carotenoid-9',10'-cleaving dioxygenase |
Sertoli cell |
- |
720152 |
1.14.19.3 | acyl-CoA 6-desaturase |
Sertoli cell |
mRNA level is upregulated by dexamethasone, follicle-stimulating hormone or cAMP |
658248 |
1.4.1.3 | glutamate dehydrogenase [NAD(P)+] |
Sertoli cell |
- |
762783 |
1.4.1.3 | glutamate dehydrogenase [NAD(P)+] |
Sertoli cell |
high GDH2 expression level |
712431 |
1.4.1.3 | glutamate dehydrogenase [NAD(P)+] |
Sertoli cell |
strong expression 0f isoform Gdh2 |
743356 |
2.7.1.105 | 6-phosphofructo-2-kinase |
Sertoli cell |
uPFK-2 |
696053 |
2.7.1.82 | ethanolamine kinase |
Sertoli cell |
high expression of isoform Eki2 at the time of sex-differentiation |
692089 |
2.7.10.2 | non-specific protein-tyrosine kinase |
Sertoli cell |
predominant expression in |
492034 |
2.7.11.1 | non-specific serine/threonine protein kinase |
Sertoli cell |
sertoli cell culture SerW3 is used |
691479 |
2.7.11.11 | cAMP-dependent protein kinase |
Sertoli cell |
- |
662873 |
2.7.2.3 | phosphoglycerate kinase |
Sertoli cell |
- |
738355, 761231 |
2.7.8.27 | sphingomyelin synthase |
Sertoli cell |
primary culture |
669649 |
2.7.8.29 | L-serine-phosphatidylethanolamine phosphatidyltransferase |
Sertoli cell |
- |
722906 |
2.7.8.29 | L-serine-phosphatidylethanolamine phosphatidyltransferase |
Sertoli cell |
very high expression |
717766 |
3.1.1.13 | sterol esterase |
Sertoli cell |
temperature-labile enzyme enriched |
133846 |
3.1.1.34 | lipoprotein lipase |
Sertoli cell |
- |
715190 |
3.1.2.22 | palmitoyl[protein] hydrolase |
Sertoli cell |
- |
730430 |
3.1.3.11 | fructose-bisphosphatase |
Sertoli cell |
- |
681034 |
3.1.3.5 | 5'-nucleotidase |
Sertoli cell |
- |
-, 715146 |
3.1.3.9 | glucose-6-phosphatase |
Sertoli cell |
- |
134945 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
Sertoli cell |
immature cell. Almost all PDE4D variants are expressed throughout the early postpartum period with a specific increase in PDE4 activity in both soluble and particulate fraction of 20 day old Sertoli cells |
678559 |
3.1.4.53 | 3',5'-cyclic-AMP phosphodiesterase |
Sertoli cell |
isolated from 10-, 20-, and 30-days-old rats. Specific increase in PDE4 activity in both the soluble and particulate subcellular fractions of 20-days-old Sertoli cells. Almost all the PDE4D isoforms, known as the main cAMP-regulated rolipramsensitive PDE in Sertoli cells, are expressed throughout the early postpartum period, whereas only the short PDE4D isoforms (PDE4D1 and PDE4D2) are transcriptionally regulated by FSH. The subcellular distribution and expression of PDE4D proteins are unaffected by the developmental status of the Sertoli cells. Only the expression of short PDE4D1 appears to be upregulated by FSH and only in 20-days-old Sertoli cells, which suggests phenotype-dependent differential regulation of Pde4d1 mRNA translation |
678559 |
3.2.1.114 | mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase |
Sertoli cell |
in the Golgi apparatus |
646640 |
3.2.1.45 | glucosylceramidase |
Sertoli cell |
- |
751127 |
3.4.11.6 | aminopeptidase B |
Sertoli cell |
- |
666799 |
3.4.17.23 | angiotensin-converting enzyme 2 |
Sertoli cell |
- |
668418 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
Sertoli cell |
- |
670341 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
Sertoli cell |
UCH-L1 may act during mitotic proliferation of spermatogonial stem cells |
664284 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
Sertoli cell |
UCH-L1 protein |
664284 |
3.4.19.12 | ubiquitinyl hydrolase 1 |
Sertoli cell |
UCHL3 |
678561 |
3.4.21.79 | granzyme B |
Sertoli cell |
- |
709759 |
3.4.21.B24 | proprotein convertase 4 |
Sertoli cell |
- |
678556 |
3.4.21.B26 | proprotein convertase 5 |
Sertoli cell |
- |
673910 |
3.4.22.15 | cathepsin L |
Sertoli cell |
cells originating from 15-day-old rats treated in utero with the anti-androgen flutamide do no longer protect adult germ cells against apoptosis. Untreated spermatocytes or spermatids exhibit increased active caspase-3 levels when co-cultured with Sertoli cells isolated from rat testes exposed in utero to the anti-androgen |
699218 |
3.4.22.B72 | SENP3 peptidase |
Sertoli cell |
- |
754964 |
3.4.23.5 | cathepsin D |
Sertoli cell |
highly expressed in cultured Sertoli cells |
731091 |
3.4.24.81 | ADAM10 endopeptidase |
Sertoli cell |
both ADAM10 and ADAM17, EC 3.4.24.86, are present during all stages of spermatogenesis |
733458 |
3.4.24.86 | ADAM 17 endopeptidase |
Sertoli cell |
both ADAM10, EC 3.4.24.81, and ADAM17 are present during all stages of spermatogenesis |
733458 |
3.4.24.B11 | ADAMTS1 endopeptidase |
Sertoli cell |
- |
755570 |
3.4.24.B12 | ADAMTS5 endopeptidase |
Sertoli cell |
- |
755570 |
3.5.3.15 | protein-arginine deiminase |
Sertoli cell |
- |
755494 |
3.6.1.6 | nucleoside diphosphate phosphatase |
Sertoli cell |
NTPDase1 |
-, 698165 |
3.6.5.5 | dynamin GTPase |
Sertoli cell |
- |
696022 |
4.4.1.16 | selenocysteine lyase |
Sertoli cell |
low enzyme level |
-, 730241 |
5.3.99.3 | prostaglandin-E synthase |
Sertoli cell |
- |
748542 |
6.2.1.3 | long-chain-fatty-acid-CoA ligase |
Sertoli cell |
- |
671606 |
6.3.5.4 | asparagine synthase (glutamine-hydrolysing) |
Sertoli cell |
- |
1718 |
7.2.2.10 | P-type Ca2+ transporter |
Sertoli cell |
- |
701312 |
7.6.2.3 | ABC-type glutathione-S-conjugate transporter |
Sertoli cell |
- |
749401 |